270-289-M001
270-289-M005
270-289-M025
89147-574EA
83.93
USD
InStock
89147-574
89147-576
89147-578
PJ-34 hydrochloride (synthetic) ≥98% (by HPLC)
PJ-34 hydrochloride
Potent, water soluble poly(ADP-ribose) polymerase (PARP) inhibitor (EC50=20nM compared to EC50=200µM of the prototypical PARP inhibitor 3-aminobenzamide). Inhibits peroxynitrite-induced cell necrosis (EC50=20nM). Has significant, dose-dependent, anti-inflammatory effects in a variety of local inflammation models and provides cardioprotection by decreasing myocardial infarct size.
White to light brown or yellow powder.
Soluble in DMSO (up to 30mg/ml) or water (up to 20mg/ml).