420-044-M025
420-044-M100
420-044-M500
89150-808EA
127.53
USD
InStock
89150-808
89150-810
89150-812
Temozolomide ≥98%
Temozolomide
AGT inhibitor
Antitumor and antiangiogenic compound. DNA alkylating agent. Induces G2/M arrest and apoptosis through adduction of a methyl group to O6 position of guanine in genomic DNA. Inactivates DNA repair protein O(6)-alkylguanine DNA alkyltransferase (AGT) in base excision repair (BER) pathway. Chemotherapeutic agent. Modifies drug resistance.