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MPLA E.coli 99,9 serotype R515 (Re), TLRgrade™ Ready-to-Use

Supplier: SAFE AND SURE NEDERLAND B.V.

581-203-L001 581-203-R500

89152-796EA 585.33 USD

89152-796 76002-222

MPLA E.coli 99,9 serotype R515 (Re), TLRgrade™ Ready-to-Use

MPLA

TLR4 activator.

Isolated from E. coli, Serotype R515 (Re mutant). Prepared by acid hydrolysis from purified E. coli, Serotype R515 (Re) LPS (isolated by a modification of the PCP extraction method), converted to the uniform salt form.

Activates TLR4 (Toll-like receptor 4). Does not activate TLR2 as determined with splenocytes and macrophages from TLR4 deficient mice. Exhibits reduced endotoxic and pyrogenic activity compared to lipid A and LPS.

Synonym: MPL-A from E. coli, Serotype R515 (Re).

Specification Test Results

Concentration	1 mg/ml
Formulation	Liquid. Sterile, ready-to-use solution in pyrogen-free double distilled water
Purity	≥99.9% (regarding protein or DNA contaminants, KDO not detectable)

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