SQ 22536 ≥99% (by TLC)
Supplier: SAFE AND SURE NEDERLAND B.V.
Adenylate cyclase inhibitor
SQ 22536 is a cell-permeable adenylate cyclase inhibitor. It inhibits cAMP production induced by prostaglandin E1 in platelet lysates (IC50=82 µM) and in intact platelets (IC50=1 µM). It has been successfully employed as a probe for the involvement of adenylate cyclase in a variety of receptor systems including those for prostaglandins and neurotransmitters. ReducesPGE2-induced inhibition of O2- production.
Formula:
C₉H₁₁N₅O MW: 205.221 g/mol |
MDL Number:
MFCD00210216 CAS Number: 17318-31-9 |
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