Bisindolylmaleimide I ≥98% (by TLC)
Supplier: SAFE AND SURE NEDERLAND B.V.
BML-EI246-0001
BML-EI246-0005
89157-860EA
107.91
USD
89157-860
76002-076
Bisindolylmaleimide I ≥98% (by TLC)
Bisindolylmaleimide I
Potent and selective protein kinase C inhibitor which has been used effectively in platelets, Swiss 3T3 fibroblasts and macrophages. Inhibitory profile: PKC, IC50=0.02µM (inhibits α, ßI, ßII and γ subtypes with similar potency); PKA, IC50=2.0µM; phosphorylase kinase, IC50=0.7µM; insulin, EGF and PDGF receptor tyrosine kinases are not inhibited at concentrations up to 50µM.
- PKC inhibitor
Red solid.
Soluble in dimethyl formamide or DMSO (10mg/ml, warm to 40°C and vortex well).
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Formula:
C₂₅H₂₄N₄O₂ MW: 412.48 g/mol Storage Temperature: Freezer |
MDL Number:
MFCD00236428 CAS Number: 133052-90-1 |