200-13-2UG
200-13-10UG
200-13-50UG
200-13-100UG
200-13-250UG
200-13-500UG
200-13-1MG
10773-048EA
144.78
USD
InStock
10773-048
10773-050
10773-052
10773-054
10773-056
10773-058
10773-060
Human Recombinant IL-13 (from E. coli)
Proteins and Peptides
IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, and also by mast cells and NK cells. Targeted deletion of IL-13 in mice resulted in impaired Th2 cell development and indicated an important role for IL-13 in the expulsion of gastrointestinal parasites. IL-13 exerts anti-inflammatory effects on monocytes and macrophages and it inhibits the expression of inflammatory cytokines such as IL-1β, TNF-α, IL-6 and IL-8. IL-13 has also been shown to enhance B cell proliferation and to induce isotype switching, resulting in increased production of IgE. Blocking of IL-13 activity inhibits the pathophysiology of asthma. Human and murine IL-13 are cross-species reactive. Recombinant Human IL-13 is a 12.6 kDa protein consisting of 115 amino acid residues.
Información para pedidos: For research use only. Not for use in diagnostic or therapeutic procedures.