200-36G-2UG
200-36G-10UG
200-36G-100UG
200-36G-250UG
200-36G-500UG
200-36G-1MG
10779-892EA
143.88
USD
InStock
10779-892
10779-894
10779-896
10779-898
10779-900
10779-902
Human Recombinant IL-36gamma (from E. coli)
Proteins and Peptides
The IL-1 family is comprised of 11 structurally related ligands, including recently re-named IL-36 α (IL-1F6), β (IL-1F8) and γ (IL-1F9). IL-36γ is highly expressed in psoriatic plaques and in tissues containing epithelial cells. IL-36γ signals through the IL-1Rrp2 (IL-1R6) receptor, which is primarily expressed on certain dendritic cells. The interaction of the IL-1Rrp2 receptor with IL-36 ligands induces dendritic cell maturation and activation. IL-36γ also functions as an agonist of NF-κB, and can stimulate the inflammatory response in bronchial epithelial cells. Recombinant Human IL-36γ (IL-1F9) is a 17.0 kDa protein containing 152 amino acid residues.
Información para pedidos: For research use only. Not for use in diagnostic or therapeutic procedures.