Chlorpromazine hydrochloride
Supplier: E. Becker & Co. GmbH
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Danger
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Chlorpromazine Hydrochloride is a phenothiazine antipsychotic; a D2 and H1 antagonist. It inhibits calmodulin-dependent stimulation of cyclic nucleotide phosphodiesterase and nitric oxide synthase and is reported to uncouple and inhibit oxidative phosphorylation at 10-3 - 10-4 M. It is possibly a photogenotoxic agent in humans. Helps to induce hypothermia in mice in the dose range of 12.5 -100 mg/kg.
Chlorpromazine demonstrates cytotoxic and antiproliferative activity against leukemic cells, but does not affect the viability of normal lymphocytes.
Phenothiazine antipsychotic; D2 dopamine receptor antagonist, H1 histamine receptor antagonist; inhibits calmodulin-dependent stimulation of cyclic nucleotide phosphodiesterase and nitric oxide synthase.
Chlorpromazine hydrochloride is a substitute for benzidine, o-dianisidine, and o-tolidine in the determination of microquantities of hemoglobin and peroxidase.
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Formula:
C₁₇H₁₉ClN₂S MW: 355.32 g/mol Melting Pt: 194…199 °C Storage Temperature: Ambient |
MDL Number:
MFCD00012654 CAS Number: 69-09-0 EINECS: 200-701-3 UN: 2811 ADR: 6.1 I |