Anti-NKX2-2 Mouse Monoclonal Antibody (CF405S) [clone: NX2/294]

Supplier: Biotium
BNC040294-100 BNC040294-500
75966-236EA 205.77 USD
75966-236 75966-238
Anti-NKX2-2 Mouse Monoclonal Antibody (CF405S) [clone: NX2/294]
Antibodies
Expression of NKX2.2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2.2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing sarcoma, and was shown to be differentially upregulated in Ewing sarcoma on the basis of array-based gene expression analysis. It acts as a valuable marker for Ewing sarcoma, with a sensitivity of 93% and a specificity of 89%, and aids in the differential diagnosis of small round cell tumors.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®405S is a blue fluorescent dye (Ex/Em 404/431 nm) with superior brightness compared to other blue dyes; it is also compatible with super-resolution imaging by SIM. Note: Conjugates of blue fluorescent dyes are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Type: Primary
Antigen: NKX2-2
Clonality: Monoclonal
Clone: Clone NX2/294
Conjugation: CF405S
Epitope:
Host: Mouse
Isotype: IgG2b, kappa
Reactivity: Chicken, Human, Mouse, Rat
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