Anti-ACTA1 (Skeletal); ACTA2 (Smooth); ACTG2 (Smooth) Mouse Monoclonal Antibody (CF405S) [clone: MSA/953]

Supplier: Biotium
BNC040953-100 BNC040953-500
75968-100EA 205.77 USD
75968-100 75968-102
Anti-ACTA1 (Skeletal); ACTA2 (Smooth); ACTG2 (Smooth) Mouse Monoclonal Antibody (CF405S) [clone: MSA/953]
Antibodies
This antibody recognizes actin of skeletal, cardiac, and smooth muscle cells. It is not reactive with other mesenchymal cells except for myoepithelium. Actin can be resolved on the basis of its isoelectric points into three distinctive components: alpha, beta, and gamma in order of increasing isoelectric point. Anti-muscle specific actin recognizes alpha and gamma isotypes of all muscle groups. Non-muscle cells such as vascular endothelial cells and connective tissues are non-reactive. Also, neoplastic cells of non-muscle-derived tissue such as carcinomas, melanomas, and lymphomas are negative.It stains tumors of smooth muscle (leiomyomas and leiomyosarcomas) as well as skeletal muscle (rhabdomyomas and rhabdomyosarcomas).

CF® dyes are Biotium's next-generation fluorescent dyes. CF®405S is a blue fluorescent dye (Ex/Em 404/431 nm) with superior brightness compared to other blue dyes; it is also compatible with super-resolution imaging by SIM. Note: Conjugates of blue fluorescent dyes are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Type: Primary
Antigen: ACTA1 (Skeletal); ACTA2 (Smooth); ACTG2 (Smooth)
Clonality: Monoclonal
Clone: Clone MSA/953
Conjugation: CF405S
Epitope:
Host: Mouse
Isotype: IgG1, kappa
Reactivity: Human, Rabbit, Rat
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