Update to Avantor’s response to the coronavirus (COVID-19) pandemic

Anti-ZAP70 Mouse Monoclonal Antibody (CF568) [clone: ZAP70/528 + 2F3.2]

Supplier: Biotium

BNC681137-100 BNC681137-500

75980-268EA 205.77 USD

75980-268 75980-270

Anti-ZAP70 Mouse Monoclonal Antibody (CF568) [clone: ZAP70/528 + 2F3.2]

Antibodies

ZAP70 is a 70 kDa protein tyrosine kinase found in T-cells and natural killer cells.Control of this protein translation is via the IgVH gene. ZAP70 protein is expressed in leukemic cells of approximately 25% of chronic lymphocytic leukemia (CLL) cases as well.Anti-ZAP70 expression is an excellent surrogate marker for the distinction between the Ig-mutated (anti-ZAP70 negative) and Ig-unmutated (anti-ZAP70 positive) CLL subtypes and can identify patient groups with divergent clinical courses. The anti-ZAP70 positive Ig-unmutated CLL cases have been shown to have a poorer prognosis.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®568 is a red fluorescent dye (Ex/Em 562/583 nm) with superior brightness and photostability. It also is compatible with super-resolution imaging by STORM and TIRF.

Type: Primary
Antigen: ZAP70
Clonality: Monoclonal
Clone: Clone ZAP70/528 + 2F3.2
Conjugation: CF568
Epitope:
Host: Mouse
Isotype: IgG's
Reactivity: Human

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