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Description:   Otoancorin, also known as OTOA, CT108 or DFNB22, is a 1,153 amino acid protein belonging to the stereocilin family. Expressed in the inner ear and restricted to the interface between the apical surface of sensory epithelia, otoancorin is suggested to act as an adhesion molecule. Otoancorin ensures the attachment of the inner ear acellular gels to the apical surface of the underlying nonsensory cells. Mutations in the gene encoding otoancorin leads to deafness autosomal recessive type 22 (DFNB22), which is a form of sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain or the area of the brain that receives sound information. Existing as three alternatively spliced isoforms, otoancorin is encoded by a gene located on human chromosome 16p12.2.
Catalog Number: 10247-578
Supplier: Bioss



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Description:   Methyl 3,5-difluoro-4-hydroxybenzoate ≥97% research grade
Catalog Number: 76942-116
Supplier: AOB CHEM USA



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Description:   Methyl 2,5-difluoro-4-piperidin-1-ylbenzoate
Catalog Number: 77414-046
Supplier: APOLLO SCIENTIFIC



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Description:   2,6-Difluoro-3-hydroxybenzaldehyde ≥97%
Catalog Number: 76897-410
Supplier: AOB CHEM USA



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Description:   C9orf96, also known as Protein kinase-like protein SgK071, is a 680 amino acid protein that belongs to the Ser/Thr protein kinase family of the protein kinase superfamily. There are three isoforms of C9orf96 that are produced as a result of alternative splicing events. The gene encoding C9orf96 maps to human chromosome 9, which consists of about 145 million bases and 4% of the human genome and encodes nearly 900 genes. Considered to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG. Familial dysautonomia is also associated with chromosome 9 though through the gene IKBKAP. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Chromosome 9 is partnered with chromosome 22 in the translocation leading to the aberrant production of BCR-ABL fusion protein often found in leukemias.
Catalog Number: 76099-618
Supplier: Bioss



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Description:   These dipeptide building blocks containing Ser- or Thr-derived oxazolidines (pseudoprolines) proved to be versatile tools for overcoming some intrinsic problems in the field of peptide chemistry. The presence of pseudoprolines within a peptide sequence results in the disruption of β-sheet structures considered as a source of intermolecular aggregation during chain elongation, thus increasing solvation and coupling kinetics in peptide assembly. Therefore, use of pseudoprolines offer new possibilities for accessing large peptides by convergent strategies and chemoselective ligation techniques. Moreover, incorporation of a pseudoproline unit facilitates cyclization of peptides.
Catalog Number: B-3540.0005BA
Supplier: Bachem Americas



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Description:   Ethyl difluoro[3-(trifluoromethyl)pyridin-2-yl]acetate ≥97%
Catalog Number: 102839-704
Supplier: Matrix Scientific



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Catalog Number: 102893-740
Supplier: Matrix Scientific



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Description:   1g CAS: 2967-54-6, MDL: MFCD09033181
Catalog Number: AAH31620-MD
Supplier: Thermo Scientific Chemicals



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MSDS SDS Certificate Certificates    
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Description:   Matrix Scientific Part Number: 046817-1G , MDL Number: MFCD09909606
Catalog Number: 101877-128
Supplier: Matrix Scientific



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Description:   MF=C7H2F2N2O2 MW=184.10 Cas=143879-77-0 MDL=MFCD00042254 25G
Catalog Number: 101788-182
Supplier: Matrix Scientific



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Description:   (2,5-Difluoro-3-nitrophenyl)methanamine 95%
Catalog Number: 77013-352
Supplier: AMBEED, INC



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Description:   2,6-Difluoro-4-hydroxybenzaldehyde 98%
Catalog Number: 77085-212
Supplier: AMBEED, INC



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Description:   2,3-Difluoro-N,N-dimethylbenzamide ≥97%
Catalog Number: 77362-330
Supplier: AOB CHEM USA



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Description:   2,4-Difluoro-5-methylaniline ≥97%
Catalog Number: 77367-962
Supplier: AOB CHEM USA



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Description:   1,2-Difluoro-4-isopentylbenzene ≥95%
Catalog Number: 77375-100
Supplier: AOB CHEM USA



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