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Methyl+3-aminocyclohexanecarboxylate+hydrochloride
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Methyl+3-aminocyclohexanecarboxylate+hydrochloride
Supplier:
Adipogen
Description:
Antibiotic. Antiprotozoal. Antimicrobial. Cytotoxic and genotoxic in various mammalian cells. Mitochondrial permeability transition pore (MPTP) activator. Apoptosis inducer. ERK and JNK signaling pathways activator. Nephrotoxic mycotoxin. Suppresses NO and iNOS expression via inhibition of the JAK/STAT-1alpha and NF-kappaB signaling pathways. Tubulin polymerization and mitotic spindle assembly inhibitor. Increases reactive oxygen species (ROS). Induces cell cycle arrest at the G0/G1 and G2/M phase.
Supplier:
MP Biomedicals
Description:
Evans Blue used in double-labeling procedure for studying axonal branching.
Supplier:
Adipogen
Description:
Mammalian antibacterial metabolite. Inhibitor of isocitrate lyase, the key enzyme of the glyoxylate cycle, essential for bacterial growth. Antimicrobial. Antibacterial. Inhibits the growth of bacteria expressing isocitrate lyase. Phosphofructokinase (PFKII) inhibitor. Suppresses glycolysis by decreasing the level of fructose 2,6-bisphosphate, resulting in decreased visceral fat. Might be involved in the regulation of metabolism. One of the most highly induced metabolites in activated macrophages. Exerts anti-inflammatory effects in vitro and in vivo. Regulates succinate levels by inhibiting succinate dehydrogenase (SDH). Regulates mitochondrial respiration and cytokine production. Might induce inflammasome activation and consequently IL-1beta secretion by generating ROS.
Supplier:
TCI America
Description:
CAS Number: 4985-85-7
MDL Number: MFCD00047971 Molecular Formula: C7H18N2O2 Molecular Weight: 162.23 Purity/Analysis Method: >90.0% (GC) Form: Clear Liquid Boiling point (°C): 207 Flash Point (°C): 138 Specific Gravity (20/20): 1.07
Supplier:
AMBEED, INC
Description:
(R)-1-Phenylethanol, Purity: 98%, CAS Number: 1517-69-7, Appearance: Liquid, Storage: Sealed in dry, Room Temperature, Size: 5g
Supplier:
Adipogen
Description:
PLX4032 (Vemurafenib, RG7204, Zelboraf, RO5185426) is a novel and potent inhibitor of B-RafV600E with an IC(50) of 31nM.
Catalog Number:
(80055-586)
Supplier:
MilliporeSigma
Description:
Useful in cell activation experiments when calcium dose-response data are not required.
Supplier:
Adipogen
Description:
LY2784544 is a potent JAK2 inhibitor with IC(50) of 3nM, effective in JAK2V617F, 8- and 20-fold selective versus JAK1 and JAK3. Phase 2.
Catalog Number:
(TCI0391-25G)
Supplier:
TCI America
Description:
(stabilized with Copper chip)
CAS Number: 624-76-0 MDL Number: MFCD00002830 Molecular Formula: C2H5IO Molecular Weight: 171.97 Purity/Analysis Method: >98.0% (GC) Form: Clear Liquid Boiling point (°C): 85 Flash Point (°C): 65 Specific Gravity (20/20): 2.21 Storage Temperature: 0-10°C
Supplier:
Adipogen
Description:
Anticancer compound. Caspase-independent, non-apoptotic cell death inducer. ATP-competitive Flt3 inhibitor. Necrosis inducer. Aurora B and C kinase inhibitor. DYRK1A and DYRK 2 (Dual-specificity tyrosine phosphorylation-regulated kinase) inhibitor. Inflammasome activator.
Supplier:
Adipogen
Description:
PF04217903 is a novel orally bio-available, small molecule tyrosine kinase inhibitor with potential anti-neoplastic activity. It is an extremely selective MET inhibitor, with an IC(50) of 4.8nM.
Catalog Number:
(102991-930)
Supplier:
Adipogen
Description:
SU-6668 is a potent ATP-competitive PDGFR, VEGF and FGFR inhibitor. It has a Ki of 8nM against PDGFR. It is an anti-angiogenic and anti-tumor agent that induces regression of established tumors.
Supplier:
Adipogen
Description:
PIK-90 is a potent PI3K inhibitor with IC(50) values of 11, 18, and 58nM for p110alpha, gamma and delta isoforms respectively. It has an IC(50) of 350nM for the p110beta isoform. It also has low mTOR activity.
Supplier:
MilliporeSigma
Description:
Inhibitor of calpain I (Ki=190nM), calpain II (Ki=220nM), cathepsin B (Ki=150nM) and cathepsin L (Ki=0.5nM). Inhibits neutral cysteine proteases and the proteasome (Ki=6µM). Protects against neuronal damage caused by hypoxia and ischemia. Inhibits apoptosis in thymocytes and metamyelocytes. Also inhibits retrovirus-induced apoptosis in L929 cells. Inhibits the proteolysis of I[kappa]B-[alpha] and I[kappa]B-[beta] by the ubiquitin-proteasome complex. Inhibits cell cycle progression at G1/S and metaphase/anaphase in CHO cells by inhibiting cyclin B degradation. Also prevents nitric oxide production by activated macrophages by interfering with transcription of the inducible nitric oxide synthase gene.
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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