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Catalog Number:
(77693-091)
Supplier:
LGC STANDARDS
Description:
2000 µg/g Ethylene Glycol Standard in Multi-grade Diesel Engine Oil, VHG, LGC Standards
Catalog Number:
(10412-468)
Supplier:
Bioss
Description:
Methylates (mono- and asymmetric dimethylation) the guanidino nitrogens of arginyl residues in several proteins involved in DNA packaging, transcription regulation, and mRNA stability. Recruited to promoters upon gene activation together with histone acetyltransferases from EP300/P300 and p160 families, methylates histone H3 at 'Arg-17' and activates transcription via chromatin remodeling. During nuclear hormone receptor activation and TCF7L2/TCF4 activation, acts synergically with EP300/P300 and either one of the p160 histone acetyltransferases NCOA1/SRC1, NCOA2/GRIP1 and NCOA3/ACTR or CTNNB1/beta-catenin to activate transcription. During myogenic transcriptional activation, acts together with NCOA3/ACTR as a coactivator for MEF2C.
Catalog Number:
(76116-410)
Supplier:
Bioss
Description:
Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH1 complex, which methylates 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di- and trimethylate 'Lys-27' of histone H3 to form H3K27me1, H3K27me2 and H3K27me3, respectively. Required for embryonic stem cell derivation and self-renewal, suggesting that it is involved in safeguarding embryonic stem cell identity. Compared to EZH1-containing complexes, it is less abundant in embryonic stem cells, has weak methyltransferase activity and plays a less critical role in forming H3K27me3, which is required for embryonic stem cell identity and proper differentiation. Sequence similarities Belongs to the histone-lysine methyltransferase family. EZ subfamily.Contains 1 SET domain.
Catalog Number:
(76116-412)
Supplier:
Bioss
Description:
Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH1 complex, which methylates 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di- and trimethylate 'Lys-27' of histone H3 to form H3K27me1, H3K27me2 and H3K27me3, respectively. Required for embryonic stem cell derivation and self-renewal, suggesting that it is involved in safeguarding embryonic stem cell identity. Compared to EZH1-containing complexes, it is less abundant in embryonic stem cells, has weak methyltransferase activity and plays a less critical role in forming H3K27me3, which is required for embryonic stem cell identity and proper differentiation. Sequence similarities Belongs to the histone-lysine methyltransferase family. EZ subfamily.Contains 1 SET domain.
Catalog Number:
(TCB0972-005ML)
Supplier:
TCI America
Description:
CAS Number: 95241-36-4
MDL Number: MFCD00059357 Molecular Formula: C12H16O3 Molecular Weight: 208.26 Purity/Analysis Method: >95.0% (GC) Form: Clear Liquid Specific Gravity (20/20): 1.04
Catalog Number:
(AAAA12385-06)
Supplier:
AMBEED, INC
Description:
4-(Methoxycarbonyl)benzoic acid, Purity: 98%, CAS Number: 1679-64-7, Appearance: Form: Crystal - Powder/Colour: White - Off white, Storage: Sealed in dry, Room Temperature, Size: 1000g
Catalog Number:
(10389-584)
Supplier:
Bioss
Description:
CYP2R1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are mono-oxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme is a microsomal vitamin D hydroxylase that converts vitamin D into the active ligand for the vitamin D receptor.Defects in CYP2R1 are a cause of 25-hydroxyvitamin D(3) deficiency, also known as pseudovitamin D(3) deficiency rickets due to 25-hydroxylase deficiency. First described in patients who had rickets at a young age despite a history of adequate vitamin D intake. The patients sera had low calcium concentrations, low phosphate concentrations, elevated alkaline phosphatase activity and low levels of 25-hydroxyvitamin D.
Catalog Number:
(TCA1011-400G)
Supplier:
TCI America
Description:
(stabilized with MEHQ)
CAS Number: 4813-57-4 MDL Number: MFCD00015091 Molecular Formula: C21H40O2 Molecular Weight: 324.55 Purity/Analysis Method: >97.0% (GC) Form: Crystal Melting point (°C): 28 Flash Point (°C): 191
Catalog Number:
(ALA163244200MG)
Supplier:
ALADDIN SCIENTIFIC
Description:
Amino functionalized polyethylene glycol (NH2-PEG-NH2) is a homobifunctional PEG derivative that can be used to modify proteins, peptides and other materials via carboxylic group (-COOH) or other amine reactive chemical groups. PEGylation can increase solubility and stability and reduce immunogenicity of peptides and proteins. It can also suppress the non-specific binding of charged molecules to the modified surfaces.
Supplier:
MilliporeSigma
Description:
Nonidet® P 40 Substitute (NP-40) solution 10%, PROTEIN GRADE® detergent, sterile-filtered
Supplier:
ALADDIN SCIENTIFIC
Description:
Amino functionalized polyethylene glycol (NH2-PEG-NH2) is a homobifunctional PEG derivative that can be used to modify proteins, peptides and other materials via carboxylic group (-COOH) or other amine reactive chemical groups. PEGylation can increase solubility and stability and reduce immunogenicity of peptides and proteins. It can also suppress the non-specific binding of charged molecules to the modified surfaces.
Catalog Number:
(10449-090)
Supplier:
Bioss
Description:
Uridine diphosphatase (UDPase) that promotes protein N-glycosylation and ATP level regulation. UDP hydrolysis promotes protein N-glycosylation and folding in the endoplasmic reticulum, as well as elevated ATP consumption in the cytosol via an ATP hydrolysis cycle. Together with CMPK1 and AK1, constitutes an ATP hydrolysis cycle that converts ATP to AMP and results in a compensatory increase in aerobic glycolysis. The nucleotide hydrolyzing preference is GDP >IDP >UDP, but not any other nucleoside di-, mono- or triphosphates, nor thiamine pyrophosphate. Plays a key role in the AKT1-PTEN signaling pathway by promoting glycolysis in proliferating cells in response to phosphoinositide 3-kinase (PI3K) signaling.
Catalog Number:
(10475-548)
Supplier:
Bioss
Description:
Histone demethylase that specifically demethylates 'Lys-9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27' nor H4 'Lys-20'. Demethylates trimethylated H3 'Lys-9' and H3 'Lys-36' residue, while it has no activity on mono- and dimethylated residues. Demethylation of Lys residue generates formaldehyde and succinate. Participates in transcriptional repression of ASCL2 and E2F-responsive promoters via the recruitment of histone deacetylases and NCOR1, respectively.
Supplier:
TCI America
Description:
CAS Number: 107-66-4
MDL Number: MFCD00015245 Molecular Formula: C8H19O4P Molecular Weight: 210.21 Form: Clear Liquid Color: Colorless Flash Point (°C): 180 Specific Gravity (20/20): 1.13
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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