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(2,2-Difluorobenzo[d][1,3]dioxol-5-yl)methanamine
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(2,2-Difluorobenzo[d][1,3]dioxol-5-yl)methanamine
Catalog Number:
(10454-302)
Supplier:
Bioss
Description:
Class E VPS protein involved in concentration and sorting of cargo proteins of the multivesicular body (MVB) for incorporation into intralumenal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome. Binds to the phospholipid lysobisphosphatidic acid (LBPA) which is abundant in MVBs internal membranes. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and enveloped virus budding (HIV-1 and other lentiviruses). Appears to be an adapter for a subset of ESCRT-III proteins, such as CHMP4, to function at distinct membranes. Required for completion of cytokinesis. Involved in HIV-1 virus budding. Can replace TSG101 it its role of supporting HIV-1 release; this function implies the interaction with CHMP4B. May play a role in the regulation of both apoptosis and cell proliferation.
Catalog Number:
(76083-948)
Supplier:
Bioss
Description:
This gene encodes a serine/threonine protein kinase that plays an important role in cellular stress response. This kinase activates certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. High levels of expression of this gene may contribute to conditions such as hypertension and diabetic nephropathy. Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Catalog Number:
(89304-026)
Supplier:
Genetex
Description:
Rabbit polyclonal antibody to NKCC2
Supplier:
Thermo Scientific Chemicals
Description:
MDL: MFCD00016144
Notes: Hardly attacked by mineral acids
Catalog Number:
(10484-708)
Supplier:
Bioss
Description:
SNAPC3 is part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. SNAPC3 binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. SNAPC3 recruits TBP and BRF2 to the U6 snRNA TATA box.
Catalog Number:
(10484-704)
Supplier:
Bioss
Description:
SNAPC3 is part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. SNAPC3 binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. SNAPC3 recruits TBP and BRF2 to the U6 snRNA TATA box.
Supplier:
BeanTown Chemical
Description:
CAS: 6153-56-6; EC No: 205-634-3; MDL No: MFCD00149102; RTECS: KI1600000
UN No: UN3261; Haz Class: 8; Packing Group: III
Crystalline; Linear Formula: HOOCCOOH·2H2O ; Molecular Formula: C2H2O4·2H2O ; MW: 126.07
Melting Point: 104-106°
Density (g/mL): 1.65
Hygroscopic
Supplier:
BeanTown Chemical
Description:
CAS: 865-49-6; EC No: 212-742-4; MDL No: MFCD00000827
UN No: UN1888; Haz Class: 6.1; Packing Group: III
Liquid; Molecular Formula: CDCl3; MW: 120.38
Melting Point: -64°; Boiling Point: 60.9°
Density (g/mL): 1.5; Refractive Index: 1.444
Light Sensitive, Moisture Sensitive
Supplier:
BeanTown Chemical
Description:
CAS: 865-49-6; EC No: 212-742-4; MDL No: MFCD00000827
UN No: UN1888; Haz Class: 6.1; Packing Group: III
Liquid; Molecular Formula: CDCl3; MW: 120.38
Melting Point: -64°; Boiling Point: 60.9°
Density (g/mL): 1.5; Refractive Index: 1.444
Light Sensitive, Moisture Sensitive
Supplier:
MilliporeSigma
Description:
A potent, cell-permeable, and irreversible inhibitor of caspase-8 (MACH, FLICE, Mch5)
Supplier:
Adipogen
Description:
Potent, cell permeable, highly specific, reversible PI(3)K (phosphoinositide 3-kinase) inhibitor. pan-class I / II / III PI3K inhibitor. Acts on the ATP-binding site of the enzyme. In solution more stable than wortmannin. Antagonizes P-glycoprotein-mediated multidrug resistance. Blocks Akt phosphorylation. Pim-1 kinase inhibitor. Autophagy inhibitor (autophagosome formation). Inhibitor of BET bromodomain proteins BRD2, BRD3 and BRD4.
Supplier:
Spectrum Chemicals
Description:
Dipotassium Dihydrogen Ethylenediaminetetraacetic Acid, Reagent
Catalog Number:
(76100-756)
Supplier:
Bioss
Description:
Potassium channel subunit that does not form functional channels by itself. Modulates KCNB1 and KCNB2 channel activity by shifting the threshold for inactivation to more negative values and by slowing the rate of inactivation. Can down-regulate the channel activity of KCNB1, KCNB2, KCNC4 and KCND1, possibly by trapping them in intracellular membranes.
Supplier:
Tonbo Biosciences
Description:
The 2.4G2 antibody is specific for a common epitope found in the extracellular regions of mouse Fc-receptors Fc-gamma II (CD32) and Fc-gamma III (CD16). These receptors are expressed by B cells, monocytes, macrophages, NK cells, dendritic cells, and neutrophils.
Supplier:
BeanTown Chemical
Description:
CAS: 4455-13-4; EC No: 224-700-2; MDL No: MFCD00009182
UN No: UN3272; Haz Class: 3; Packing Group: III
Liquid; Linear Formula: CH3SCH2CO2CH2CH3; Molecular Formula: C5H10O2S; MW: 134.20
Boiling Point: 70-72°/25 mmHg; Flash point: 59°C (138°F)
Density (g/mL): 1.043; Refractive Index: 1.459
Moisture Sensitive
Supplier:
BeanTown Chemical
Description:
CAS: 152-18-1; MDL No: MFCD00014888
UN No: UN3278; Haz Class: 6.1; Packing Group: III
Liquid; Linear Formula: P(S)(OCH3)3; Molecular Formula: C3H9O3PS; MW: 156.15
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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