3-(Trifluoromethyl)piperidin-2-one
Catalog Number:
(10387-018)
Supplier:
Bioss
Description:
The protein encoded by this gene is a regulatory protein involved in mitosis. The gene product complexes with p34(cdc2) to form the maturation-promoting factor (MPF). Two alternative transcripts have been found, a constitutively expressed transcript and a cell cycle-regulated transcript, that is expressed predominantly during G2/M phase. The different transcripts result from the use of alternate transcription initiation sites. [provided by RefSeq, Jul 2008].
Catalog Number:
(10232-038)
Supplier:
Bioss
Description:
Receptor for RTN4, OMG and MAG. Mediates axonal growth inhibition and may play a role in regulating axonal regeneration and plasticity in the adult central nervous system (By similarity). Acts in conjunction with RTN4 and LIGO1 in regulating neuronal precursor cell motility during cortical development.
Catalog Number:
(10401-994)
Supplier:
Bioss
Description:
Cullin 1 may be involved in the degradation of positive cell cycle regulators (for example G1 cyclins in yeast). Human cullin 1 forms a complex with Skp1 and the F box protein Skp2, which is thought to play a role in the ubiquitination of G1 regulatory proteins, as its homolog does in yeast.
Catalog Number:
(10666-178)
Supplier:
Bioss
Description:
TRPM6 is an essential ion channel and serine/threonine-protein kinase, and is crucial for magnesium homeostasis. TRPM6 also has an important role in epithelial magnesium transport and in the active magnesium absorption in the gut and kidney. The various isoforms of the type M6-kinase lack the ion channel region.
Catalog Number:
(10408-046)
Supplier:
Bioss
Description:
Lamins are nuclear membrane proteins that serve to maintain specific cellular functions, such as DNA replication and chromatin organization. Lamin B receptor (LBR) is an integral protein of the nuclear envelope inner membrane. It is phosphorylated by CDC2 protein kinase in mitosis when the inner nuclear membrane breaks down into vesicles that dissociate from the lamina and the chromatin. It is phosphorylated by different protein kinases in interphase when the membrane is associated with these structures. The cleavage of lamins results in nuclear disregulation and cell death.
Supplier:
Biolegend
Description:
FITC anti-human CD44 [BJ18]; Isotype: Mouse IgG1, κ; Reactivity: Human, African Green, Baboon, Cynomolgus, Rhesus; Apps: FC; Size: 100 tests
Catalog Number:
(10332-708)
Supplier:
Bioss
Description:
The protein encoded by this gene belongs to the CDK subfamily of the Ser/Thr protein kinase family. The CDK subfamily members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and are known to be essential for cell cycle progression. This kinase has been shown to play a role in cellular proliferation and its function is limited to cell cycle G2-M phase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
Catalog Number:
(10463-188)
Supplier:
Bioss
Description:
The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene.
Catalog Number:
(10467-484)
Supplier:
Bioss
Description:
This gene uses alternative splicing to generate two different proteins- high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. In contrast to HMWK, LMWK is not involved in blood coagulation. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009].
Supplier:
Biolegend
Description:
FITC anti-mouse/rat/human CD27 [LG.3A10]; Isotype: Armenian Hamster IgG; Reactivity: Mouse, Rat, Human; Apps: FC; Size: 500 μg
Supplier:
Biolegend
Description:
FITC anti-human HLA-DR [LN3]; Isotype: Mouse IgG2b, κ; Reactivity: Human, Cross-Reactivity: Rhesus; Apps: FC; Size: 100 tests
Catalog Number:
(75842-430)
Supplier:
BIOGEMS INTERNATIONAL INC.
Description:
The 2A3 antibody was obtained by hybridization of MouseNS-1 myeloma cells with spleen cells harvested from BALB/c mice immunized with phytohemagglutinin-activated human T cells. The 2A3 antibody is a CD25 clone and used as an Isotype Control for rat IgG2a antibodies.
Catalog Number:
(10364-602)
Supplier:
Bioss
Description:
This gene encodes a protein that belongs to the pi3/pi4-kinase family of proteins. The gene product is an enzyme that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring. It is an important modulator of extracellular signals, including those elicited by E-cadherin-mediated cell-cell adhesion, which plays an important role in maintenance of the structural and functional integrity of epithelia. In addition to its role in promoting assembly of adherens junctions, the protein is thought to play a pivotal role in the regulation of cytotoxicity in NK cells. The gene is located in a commonly deleted segment of chromosome 7 previously identified in myeloid leukemias. [provided by RefSeq, Jul 2008].
Catalog Number:
(103265-492)
Supplier:
Southern Biotechnology
Description:
FITC Anti-Mouse IL-10 antibody for use in flow cytometry and immunohistochemistry / immunocytochemistry assays.
Catalog Number:
(100244-012)
Supplier:
Southern Biotechnology
Description:
The monoclonal antibody NIMR-4 reacts specifically with a non-polymorphic I-A-encoded epitope on MHC Class II antigens. Class II antigens are predominantly expressed on antigen-presenting cells including B lymphocytes, macrophages, dendritic cells, and certain epithelial cells.
Catalog Number:
(10422-344)
Supplier:
Bioss
Description:
TACC2 is a conserved family of centrosome and microtubule interacting proteins that are implicated in cancer. This gene encodes a protein that concentrates at centrosomes throughout the cell cycle. This gene lies within a chromosomal region associated with tumorigenesis. Expression of this gene is thought to affect the progression of breast tumors. Expression of this gene is also induced by erythropoietin.
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