1,4-Cyclohexanedicarboxylic+acid+(mixture+of+cis+and+trans+isomer
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Catalog Number:
(10278-640)
Supplier:
Bioss
Description:
The tripartite motif (TRIM) family of proteins are characterized by a conserved TRIM domain that includes a coiled-coil region, a B-box type zinc finger, one RING finger and three zinc-binding domains. Staf-50 (50 kDa-stimulated trans-acting factor), also known as TRIM22 (tripartite motif-containing 22), RNF94 or GPSTAF50, is a 498 amino acid cytoplasmic protein that belongs to the TRIM family and, characteristic of TRIM family members, contains one RING-type zinc finger, one B box-type zinc finger and one SPRY domain. Induced by IFN-å and IFN-∫, Staf-50 is strongly expressed in ovary, spleen, thymus and peripheral blood leukocytes where it is thought to mediate the antiviral effects of IFN proteins. Additionally, Staf-50 is present in leukemic cells, suggesting a role in cancer formation and metastasis. Staf-50 exists as two alternatively spliced isoforms which are encoded by a gene that maps to human chromosome 11.
Catalog Number:
(10115-064)
Supplier:
Prosci
Description:
Polyclonal, Host: Goat; Immunogen: Defb19 Antibody was raised against a 14 amino acid sequence near the C-Terminus of Defb19 (mouse); Applications: ELISA
Supplier:
AMBEED, INC
Description:
Succinic acid, Purity: 99.5%, CAS Number: 110-15-6, Appearance: White to Off-white Powder or Crystals, Storage: Sealed in dry, Room Temperature, Size: 1000G
Catalog Number:
(75928-160)
Supplier:
Rockland Immunochemical
Description:
GOLGA5 (Golgi autoantigen, subfamily A, member 5), also known as GOLGA84, RFG5 (RET-fused gene 5 protein) or GOLIM5, is a ubiquitously expressed single-pass type II coiled-coil membrane protein that is involved in maintaining Golgi structure (1). It is localized to the Golgi apparatus and predominantly found on membranes at the cis side of the Golgi stack (1,2). As a mitotic phosphoprotein, GOLGA5 binds to active Rab 1 and associates with CASP (an isoform of CDP) in a golgin-tethering complex that is believed to play a role in intra-Golgi retrograde transport (3,4). Defects in GOLGA5 are a cause of thyroid papillary carcinoma (TPC) (5).
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
di-Sodium succinate hexahydrate 97%
Catalog Number:
(SXLCS-5783)
Supplier:
SPEX CERTIPREP LLC
Description:
LC & LC/MS single-component organic standard.
Catalog Number:
(10252-178)
Supplier:
Bioss
Description:
Adaptins are heterotetrameric subunits of adaptors, which are complexes involved in the formation of Clathrin-coated pits for vesicle-mediated endocytosis. Clathrin and its associated heterotetrameric protein complexes make up the main protein components of the coat surrounding the cytoplasmic face of coated vesicles. The Adaptin family, comprising a, b, and g classes, is also responsible for the transport of ligand-receptor complexes from plasma membranes and the trans-Golgi network to lysosomes. Two main types of adaptor proteins (APs), AP-1 and AP-2, are found in Clathrin-coated structures located at the Golgi complex and the plasma membrane of mammalian cells, respectively. Adaptor protein complex 2 (AP-2) is composed of two large Adaptins (a1A/AP2A1 and b1/AP2B1), a medium Adaptin (m2/AP-2m1) and a small Adaptin (s2 long/AP2S1). AP-2m1, a 435 amino acid protein, links Clathrin to receptors in coated vesicles.
Catalog Number:
(76082-912)
Supplier:
Bioss
Description:
The ankyrin repeat and SOCS box containing (ASB) protein family is comprised of members which each contain "SOCS boxes" but differ from other families of protein in the motifs they contain upstream of the SOCS box. SOCS boxes are carboxy terminal regions of homology found in the suppressor of cytokine signaling family of proteins. The box region is thought to be the point of interaction between SOCS proteins and E3 ubiquitin ligases. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. The gene is induced by all trans retinoic acid. In myeloid leukemia cells, the expression of this encoded protein has been shown to induce growth inhibition and chromatin condensation. Multiple alternatively spliced transcript variants have been described for this gene but their full length sequences are not known.
Catalog Number:
(10260-296)
Supplier:
Bioss
Description:
Located in the mitochondrial inner membrane, mitochondrial complex I is the first and largest enzyme in the electron transport chain of oxidative phosphorylation. By oxidizing NADH that is produced in the Krebs cycle, this complex utilizes the two electrons to reduce ubiquinone to ubiquinol, thereby initiating the passage of electrons to successive complexes and ultimately leading to the reduction of oxygen to water. Mitochondrial complex I consists of over 40 subunits and is of considerable clinical interest since defects in any of the subunits can lead to various myopathies and neuropathies. As a subunit of mitochondrial complex I, NDUFS7 (NADH dehydrogenase [ubiquinone] iron-sulfur protein 7), also designated NADH-ubiquinone oxidoreductase 20 kDa subunit, is a 213 amino acid protein that is suggested to be required for catalytic activity. Defects in the gene encoding NDUFS7 are the cause of Leigh syndrome, a severe neurological disorder that is characterized by bilaterally symmetrical necrotic lesions in subcortical brain regions.
Catalog Number:
(10116-054)
Supplier:
Prosci
Description:
Polyclonal antibody Hand2 Host: Goat immunogen: Hand2 antibody was raised against a 14 amino acid synthetic peptide near the C-Terminus of Hand2. Application: ELISA
Supplier:
MP Biomedicals
Description:
Soluble in water (20 mg/mL) or ethanol (5 mg/mL). Creates a bluish-red solution with a yellow fluorescence.
Supplier:
TLC PHARMACEUTICAL STANDARD LTD
Description:
Pharmaceutical Standards, Clopidogrel EP Impurity E (S-Isomer)
Supplier:
BeanTown Chemical
Description:
CAS: 6106-21-4; EC No: 205-778-7; MDL No: MFCD00149117; RTECS: WM7751000
Crystalline; Linear Formula: NaOOCCH2CH2COONa·6H2O ; Molecular Formula: C4H4Na2O4·6H2O ; MW: 270.14
Hygroscopic
Catalog Number:
(TCA0272-025G)
Supplier:
TCI America
Description:
CAS Number: 94-14-4
MDL Number: MFCD00017110 Molecular Formula: C11H15NO2 Molecular Weight: 193.25 Purity/Analysis Method: >98.0% (GC,T) Form: Crystal Melting point (°C): 65
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 042027-5G , MDL Number: MFCD01321011
Catalog Number:
(ALA170915-1G)
Supplier:
ALADDIN SCIENTIFIC
Description:
1-Amino-4-oxocyclohexanecarboxylic acid ethylene ketal ≥95%
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