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2-(2,4-Difluorophenyl)pyridine
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2-(2,4-Difluorophenyl)pyridine
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Your search request has been modified to limit number of results. Your search was - 1,4-Cyclohexanedicarboxylic+acid+(mixture+of+cis+and+trans+isomers) |
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Catalog Number:
(101189-698)
Supplier:
BioVendor
Description:
Cyclophilins belong to a group of proteins that have peptidyl-prolyl cis-trans isomerase activity; such proteins are collectively known as immunophilins and also include the FK-506-binding proteins and the parvulins. Cyclophilins are found in all cells of all organisms studied, in both prokaryotes and eukaryotes. Human have a total of 16 cyclophilin proteins. Cyclophilins also have varying degrees of affinity for the immunosuppressive drug Cyclosporine A (CsA), a cyclic 11-amino-acid peptide produced by fungus Tolypocladium infantum. Cyclophilin A, in particular, is the major intracellular receptor for CsA. Cyclophilin A (CYPA) is the first member of the cyclophilins to be identified in mammals. Human genes of CYPA, also known as Cyp18, are located on chromosome 7p11.2-p13 and encode the protein, which consists of 165 amino acid residues with a relative molecular mass approximately 18 kDa. Human CYPA has an eight-stranded antiparallel β-barrel structure, with two α-helices enclosing the barrel from either side. Seven aromatic and other hydrophobic residues form a compact hydrophobic core within the barrel, usually in the area where CsA binds. A loop from Lys118 ti His126 and four β-strands (β3-β6) make up the binding site for CsA. In mammals, the CsA-CYPA complex binds to and inhibits calcineurin, a calcium-calmodulin-activated serine/threonine-specific protein phosphatase. The inhibition of calcineurin blocks the translocation of nuclear factor of activated T cells from the cytosol to the nucleus, thus preventing the transcription of genes encoding cytokines such as interleukin-2.
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
Cinnamyl alcohol ≥98% (trans-isomers)
Catalog Number:
(89149-298)
Supplier:
Enzo Life Sciences
Description:
R,S-Sulforaphane is a synthetic version of the naturally occurring compound, R-sulforaphane, from Broccoli. It is a racemic mixture of both the R and S isomers.
Potent, selective inducer of phase II detoxification enzymes. Inhibits chemically induced mammary tumor formation in rats. Inhibits LPS-induced HMGB1 (high mobility group box 1) secretion. 
Catalog Number:
(77677-745)
Supplier:
LGC STANDARDS
Description:
1,2-Cyclohexanedicarboxylic acid, bis(2-ethylhexyl) ester, Dr. Ehrenstorfer, LGC Standards
Catalog Number:
(34172-138)
Supplier:
MilliporeSigma
Description:
For use in the Van Gieson connective tissue stain and Mallory's aniline blue connective tissue stain
Supplier:
Bachem Americas
Description:
Sequence: Boc-His(Bzl)-OH
Supplier:
AMBEED, INC
Description:
1-(2-Chlorophenyl)-2-nitroethylene, Purity: 98% (only trans-), CAS Number: 3156-34-1, Appearance: White to Yellow to Tan Powder or Crystals, Storage: Inert atmosphere, Room Temperature, Size: 25g
Supplier:
BeanTown Chemical
Description:
CAS: 110-17-8; EC No: 203-743-0; MDL No: MFCD00002700; RTECS: LS9625000
Solid; Linear Formula: HO2CCH=CHCO2H; Molecular Formula: C4H4O4; MW: 116.07
Melting Point: 298-300° (sublimes); Flash point: 230°C (446°F)
Supplier:
Thermo Scientific Chemicals
Description:
Trifluoromethyl(perfluorodecahydronaphthalene). Grade:tech. 85, Melting Point C-70*. Boiling Point C:159-160*. C11F20. 51294-16-7. Balance other fluorocarbons.
Supplier:
MP Biomedicals
Description:
Protein kinase C inhibitor (IC50 = 50-200 µM depending on assay conditions in MCF-7 cells or IC50 = 100 µM in rat brain). The PKC inhibition is also dependent on the phosopholipid concentration. Also inhibits both calmodulin-dependent and calmodulin-independent Ca2+-, Mg2+-ATPase. Tamoxifen is a selective estrogen response modifier (SERM), anti-angiogenetic factor. It is a prodrug that is metabolized to active metabolites 4-hydroxytamoxifen (4-OHT) and endoxifen by cytochrome P450 isoforms CYP2D6 and CYP3A4. In breast cancer, the gene repressor activity of tamoxifen against ERBB2 is dependent upon PAX2. Blocks estradiol-stimulated VEGF production in breast tumor cells.
Tamoxifen has been used to facilitate the recombination of ect2flox allele in mouse organs. It has also been used to study its effect on lipopolysaccharide (LPS)-induced microglial activation Tamoxifen is a Protein kinase C inhibitor. It induces apoptosis in human malignant glioma cell lines. Tamoxifen and its metabolite 4-hydroxytamoxifen are selective estrogen response modifiers (SERMs) that act as estrogen antagonists in mammary gland. Blocks estradiol-stimulated VEGF production in breast tumor cells.
Catalog Number:
(10395-184)
Supplier:
Bioss
Description:
12 Lipoxygenase is a non heme iron containing dioxygenase which stereospecifically incorporates molecular oxygen into cis,cis-1,4-pentadiene containing polyunsaturated fatty acids. Murine leukocyte 12 Lipoxygenase oxidizes arachidonic acid to 12(S)-HpETE and 15(S)-HpETE in a ratio of 3:1. Murine leukocyte 12 Lipoxygenase is a 75 kDa protein which is 58% homologous to murine platelet 12 Lipoxygenase, and 70% homologous to porcine leukocyte 12 Lipoxygenase.
Supplier:
TCI America
Description:
CAS Number: 122-20-3
MDL Number: MFCD00004533 Molecular Formula: C9H21NO3 Molecular Weight: 191.27 Purity/Analysis Method: >98.0% (T) Form: Crystal Boiling point (°C): 305 Flash Point (°C): 160
Supplier:
Thermo Scientific Chemicals
Description:
Main effects in tissue culture systems include control of shoot growth and formation, cell division and inhibition of leaf senescence
Supplier:
TCI America
Description:
MDL Number: MFCD00008236
Molecular Formula: C5H13N Molecular Weight: 87.17 Purity/Analysis Method: >98.0% (GC) Form: Clear Liquid Flash Point (°C): -1 Specific Gravity (20/20): 0.76
Catalog Number:
(89139-254)
Supplier:
Biotium
Description:
5-(and-6)-Carboxy-2′,7′-dichlorofluorescein diacetate is membrane-permeant and thus can be loaded into cells via incubation. The diacetate is readily hydrolyzed to 5-(and-6)-carboxy-2′,7′-dichlorofluorescein (51015) by intracellular esterases.
Supplier:
MilliporeSigma
Description:
Due to its specific melting range the product may be solid, liquid, a solidified melt or a supercooled melt.
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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