1-(2,3-Difluoro-4-iodophenyl)ethanol
Supplier:
Adipogen
Description:
Mammalian antibacterial metabolite. Inhibitor of isocitrate lyase, the key enzyme of the glyoxylate cycle, essential for bacterial growth. Antimicrobial. Antibacterial. Inhibits the growth of bacteria expressing isocitrate lyase. Phosphofructokinase (PFKII) inhibitor. Suppresses glycolysis by decreasing the level of fructose 2,6-bisphosphate, resulting in decreased visceral fat. Might be involved in the regulation of metabolism. One of the most highly induced metabolites in activated macrophages. Exerts anti-inflammatory effects in vitro and in vivo. Regulates succinate levels by inhibiting succinate dehydrogenase (SDH). Regulates mitochondrial respiration and cytokine production. Might induce inflammasome activation and consequently IL-1beta secretion by generating ROS.
Supplier:
AMBEED, INC
Description:
(R)-1-Phenylethanol, Purity: 98%, CAS Number: 1517-69-7, Appearance: Liquid, Storage: Sealed in dry, Room Temperature, Size: 5g
Supplier:
Adipogen
Description:
TG-89 is a JAK inhibitor. It has IC(50) values of 6, 25, 17 and 169nM against JAK2, FLT3, RET and JAK3 respectively.
Supplier:
TCI America
Description:
CAS Number: 4985-85-7
MDL Number: MFCD00047971 Molecular Formula: C7H18N2O2 Molecular Weight: 162.23 Purity/Analysis Method: >90.0% (GC) Form: Clear Liquid Boiling point (°C): 207 Flash Point (°C): 138 Specific Gravity (20/20): 1.07
Supplier:
Thermo Scientific Chemicals
Description:
alpha-Hydroxy-2,4-difluorophenylacetic acid. Grade:97, Melting Point C122-124*. Boiling Point C:NA. C8H6F2O3. 132741-30-1. IRRITANT
Supplier:
Adipogen
Description:
LY2784544 is a potent JAK2 inhibitor with IC(50) of 3nM, effective in JAK2V617F, 8- and 20-fold selective versus JAK1 and JAK3. Phase 2.
Catalog Number:
(80055-586)
Supplier:
MilliporeSigma
Description:
Useful in cell activation experiments when calcium dose-response data are not required.
Supplier:
TCI America
Description:
CAS Number: 455-86-7
MDL Number: MFCD00011672 Molecular Formula: C7H4F2O2 Molecular Weight: 158.10 Purity/Analysis Method: >98.0% (GC,T) Form: Crystal Melting point (°C): 123
Catalog Number:
(TCI0391-25G)
Supplier:
TCI America
Description:
(stabilized with Copper chip)
CAS Number: 624-76-0 MDL Number: MFCD00002830 Molecular Formula: C2H5IO Molecular Weight: 171.97 Purity/Analysis Method: >98.0% (GC) Form: Clear Liquid Boiling point (°C): 85 Flash Point (°C): 65 Specific Gravity (20/20): 2.21 Storage Temperature: 0-10°C
Supplier:
Thermo Scientific Chemicals
Description:
Bromodifluoromethyl diethyl phosphonate Diethyl bromodifluoromethanephosphonate. Grade: 97. Melting Point C. Boiling Point C: 99-102*/16mm. C5H10BrF2O3P. 65094-22-6. HARMFUL IRRITANT
Supplier:
AMBEED, INC
Description:
5-Amino-1-(2-hydroxyethyl)pyrazole, Purity: 98%, CAS Number: 73616-27-0, Appearance: Form: Crystal - Powder/Colour: White - Pale reddish yellow - Yellow, Storage: Keep in dark place, Sealed in dry, 2-8 C, Size: 25g
Catalog Number:
(76514-244)
Supplier:
VWR International
Description:
These VWR® Plus glass door laboratory refrigerators offer versatile cold storage solutions with superior temperature control.
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Supplier:
Adipogen
Description:
CYC116 is an orally active small molecule multi-kinase inhibitor with anti-neoplastic activity. CYC116 inhibits Aurora kinases A/B and vascular endothelial growth factor receptor 2 (VEGFR2), resulting in disruption of the cell cycle, rapid cell death, and the inhibition of angiogenesis.
Supplier:
Adipogen
Description:
Neratinib (HKI-272) is an orally available, irreversible tyrosine kinase inhibitor with IC(50) values of 59nM and 92nM for HER2 and EGFR, respectively. It is in development for the treatment of early- and late-stage HER2-positive breast cancer.
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