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Disodium+naphthalene-1,5-disulphonate
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Disodium+naphthalene-1,5-disulphonate
Catalog Number:
(10078-902)
Supplier:
Prosci
Description:
MECT1 (also known as MucoEpidermoid Carcinoma Translocated 1, Transducer of regulated cAMP response element-binding protein 1, TORC1, and Transducer of CREB protein 1) is a nuclear protein that functions as a transcriptional coactivator for CREB1, which activates transcription through both consensus and variant cAMP response element (CRE) sites. MECT1does not appear to modulate CREB1 DNA-binding activity but enhances the interaction of CREB1 with TAF4/TAFII-130. MECT1 translocates with MAML2 (MasterMind-Like Protein 2) to yield a fusion oncogene: t(11;19) (q21;p13). This translocation occurs in mucoepidermoid carcinomas, benign Warthin tumors and clear cell hidradenomas. The novel fusion product that results disrupts the Notch signaling pathway. The fusion protein consists of the N-terminus of MECT1 joined to the C-terminus of MAML2. The reciprocal fusion protein consisting of the N-terminus of MAML2 joined to the C-terminus of MECT1 has been detected in a small number of mucoepidermoid carcinomas. Multiple isoforms have been reported for the MECT1 protein.
Supplier:
Spectrum Chemicals
Description:
Saccharin Sodium, Dihydrate, Powder, USP is a pharmaceutical grade substance whose most common use is as an artificial sweetener. All Spectrum Chemical USP products are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP) per 21CFR part 211 in FDA registered and inspected facilities
Catalog Number:
(PI88427)
Supplier:
Invitrogen
Description:
Thermo Scientific Heavy and Light Amino Acids are used to specifically analyze protein expression by mass spectrometry using stable isotope labeling with amino acids in cell culture (SILAC) quantification kits.
Supplier:
VWR International
Description:
Smooth-edged spreaders are excellent for spreading cultures and liquids without unwanted cutting, scraping, or gouging of agar during inoculation.
Supplier:
AMBEED, INC
Description:
Sodium 3-oxo-3H-benzo[d]isothiazol-2-ide 1,1-dioxide xhydrate, Purity: 97%, CAS Number: 82385-42-0, Appearance: Colorless or White Powder or Crystals, Storage: Inert atmosphere, Room Temperature, Size: 500G
Catalog Number:
(PI89989)
Supplier:
Invitrogen
Description:
Heavy and Light Amino Acids are used to specifically analyze protein expression by mass spectrometry using stable isotope labeling with amino acids in cell culture (SILAC) quantification kits. Store at 2 - 8ËšC.
Supplier:
ALADDIN SCIENTIFIC
Description:
Biebrich scarlet Dye content ~60 %
Supplier:
Spectrum Chemicals
Description:
Sodium Saccharin, Dihydrate, Granular, FCC is a white crystalline solid whose most common use is as an artificial sweetener. The FCC grade meets the requirements of the Food Chemical Codex indicates and is suitable for all food, beverage and nutritional supplement applications. Spectrum Chemical offers over 300 Food grade chemical ingredients packaged in laboratory size bottles to production drum quantities and are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP) per 21CFR part 211 in FDA registered and inspected facilities
Catalog Number:
(77388-360)
Supplier:
AOB CHEM USA
Description:
4-Bromo-3-chloro-2,4'-difluoro-1,1'-biphenyl ≥97%
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
L-Arginine hydrochloride 98+%
Catalog Number:
(EM8.16001.0100)
Supplier:
TCI America
Description:
2-(3,4-Dimethoxybenzamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide, Purity: >98%(HPLC), CAS: 301305-73-7, MF: C18H20N2O4S, MW: 360.43, Synonyms: Flt-3 Inhibitor, TCS 359, Form: Crystal - Powder, Size: 25MG
Supplier:
VWR International
Description:
Durable round bottom flasks with 3 necks at an angle.
Catalog Number:
(BDH1162-4LP)
Supplier:
VWR International
Description:
Clear, colorless liquid. Denatured with 3.4–4.0% methanol and 3.6–4.4% 2-propanol. Suitable for cytology and histology.
Catalog Number:
(76012-066)
Supplier:
Prosci
Description:
SUMO4 is a member of the SUMO gene family. This family of small ubiquitin-related modifiers covalently modify target lysines in proteins and control the target proteins' subcellular localization, stability, or activity. Upon oxidative stress, SUMO4 conjugates to various anti-oxidant enzymes, chaperones, and stress defense proteins. This protein may also conjugate to NFKBIA, TFAP2A and FOS, negatively regulating their transcriptional activity, and to NR3C1, positively regulating its transcriptional activity. Covalent attachment to SUMO4 substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I. In contrast to SUMO1, SUMO2 and SUMO3, SUMO4 seems to be insensitive to sentrin-specific proteases due to the presence of Pro-90. This may impair processing to mature form and conjugation to substrates. SUMO4 is located in the cytoplasm and specifically modifies IKBA, leading to negative regulation of NF-kappa-B-dependent transcription of the IL12B gene. The M55V substitution has been associated with type I diabetes.
Catalog Number:
(470313-902)
Supplier:
VWR International
Description:
Quick Benchtop Sterilization.
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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