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Ethyl+5-bromo-\\\\u03B1-oxobenzo[b]thiophene-2-acetate
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Ethyl+5-bromo-\\\\u03B1-oxobenzo[b]thiophene-2-acetate
Catalog Number:
(102552-802)
Supplier:
BioVendor
Description:
Visinin like protein 1 (VILIP-1, VLP-1 or VSNL-1) is a cytoplasmic protein of low molecular weight (approximately 22 kDa) consisting of 191 amino acid residues. It belongs to the visinin/recoverin subfamily of neuronal calcium sensor proteins involved in calcium-dependent signal transduction mechanisms in neurons. It is found primarily in the brain, in nerve cells, but it also has a peripheral distribution in liver, lung, kidney, spleen, pancreas and colon. When localized at the membrane, it modulates various cellular signal transduction pathways, including cyclic adenosine monophosphate (cAMP)- and cyclic guanosine monophosphate (cGMP)-signaling in neural cells, human embryonic kidney cells, the pancreatic β cell line MIN6, and various skin tumor cell lines. It contains four internal repeats of 36–38 amino-acids, each containing a potential EF-hand domain. Two of the four EF-hand Ca2+-binding motifs of VILIP-1 are able to bind either Ca2+ or Mg2+in a non-cooperative manner. Binding of Ca2+ leads to specific conformational changes in the protein and this may regulate the interaction of VILIP with intracellular target molecules. VILIP-1 has been identified as a potential biomarker for brain injury and several neurodegenerative diseases. VILIP-1-expressing cells appear to be vulnerable to neurotoxic insults. As a result, the protein is released into the cerebrospinal fluid (CSF), and can be used as a biomarker for stroke and Alzheimer’s disease.
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 050277-500MG , MDL Number: MFCD13560678
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 050289-500MG , MDL Number: MFCD13560690
Catalog Number:
(101892-370)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 050617-2.5G , MDL Number: MFCD13561013
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 050174-500MG , MDL Number: MFCD13560575
Catalog Number:
(77686-537)
Supplier:
AMBEED, INC
Description:
(R)-2,6,6-Trimethyl-4-(((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)cyclohex-1-ene-1-carbaldehyde ≥95%
Catalog Number:
(101923-380)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 062144-500MG , MDL Number: MFCD12198016
Catalog Number:
(101923-320)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 062114-500MG , MDL Number: MFCD12197989
Catalog Number:
(101892-362)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 050615-2.5G , MDL Number: MFCD13561011
Catalog Number:
(101815-382)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 023121-500MG , MDL Number: MFCD08688477
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 050269-2.5G , MDL Number: MFCD13560670
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 049883-2.5G , MDL Number: MFCD13560285
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 050831-2.5G , MDL Number: MFCD13561211
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 050264-2.5G , MDL Number: MFCD13560665
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 050268-2.5G , MDL Number: MFCD13560669
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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