(7-Azabenzotriazol-1-yloxy)tri(1-pyrrolidinyl)phosphonium+hexaflu
Catalog Number:
(102552-802)
Supplier:
BioVendor
Description:
Visinin like protein 1 (VILIP-1, VLP-1 or VSNL-1) is a cytoplasmic protein of low molecular weight (approximately 22 kDa) consisting of 191 amino acid residues. It belongs to the visinin/recoverin subfamily of neuronal calcium sensor proteins involved in calcium-dependent signal transduction mechanisms in neurons. It is found primarily in the brain, in nerve cells, but it also has a peripheral distribution in liver, lung, kidney, spleen, pancreas and colon. When localized at the membrane, it modulates various cellular signal transduction pathways, including cyclic adenosine monophosphate (cAMP)- and cyclic guanosine monophosphate (cGMP)-signaling in neural cells, human embryonic kidney cells, the pancreatic β cell line MIN6, and various skin tumor cell lines. It contains four internal repeats of 36–38 amino-acids, each containing a potential EF-hand domain. Two of the four EF-hand Ca2+-binding motifs of VILIP-1 are able to bind either Ca2+ or Mg2+in a non-cooperative manner. Binding of Ca2+ leads to specific conformational changes in the protein and this may regulate the interaction of VILIP with intracellular target molecules. VILIP-1 has been identified as a potential biomarker for brain injury and several neurodegenerative diseases. VILIP-1-expressing cells appear to be vulnerable to neurotoxic insults. As a result, the protein is released into the cerebrospinal fluid (CSF), and can be used as a biomarker for stroke and Alzheimer’s disease.
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 050277-500MG , MDL Number: MFCD13560678
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 050289-500MG , MDL Number: MFCD13560690
Catalog Number:
(101892-370)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 050617-2.5G , MDL Number: MFCD13561013
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 050174-500MG , MDL Number: MFCD13560575
Catalog Number:
(77686-537)
Supplier:
AMBEED, INC
Description:
(R)-2,6,6-Trimethyl-4-(((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)cyclohex-1-ene-1-carbaldehyde ≥95%
Catalog Number:
(101923-380)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 062144-500MG , MDL Number: MFCD12198016
Catalog Number:
(101923-320)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 062114-500MG , MDL Number: MFCD12197989
Catalog Number:
(101892-362)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 050615-2.5G , MDL Number: MFCD13561011
Catalog Number:
(101815-382)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 023121-500MG , MDL Number: MFCD08688477
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 050269-2.5G , MDL Number: MFCD13560670
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 049883-2.5G , MDL Number: MFCD13560285
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 050831-2.5G , MDL Number: MFCD13561211
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 050264-2.5G , MDL Number: MFCD13560665
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 050268-2.5G , MDL Number: MFCD13560669
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This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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The original product is no longer available. The replacement shown is available.
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