4-(3,4-Dichlorophenyl)thiazol-2-amine
Supplier:
ALADDIN SCIENTIFIC
Description:
3-(4-Methylphenyl)-1H-pyrazol-5-amine ≥98%
Supplier:
Adipogen
Description:
Quizartinib (AC220) is a second-generation FLT3 inhibitor that has shown promising activity in AML in Phase II clinical trials. It inhibits mutant and wild-type FLT3 in vivo at 0.1 and 0.5µM, respectively, and has shown favorable activity and tolerability in phase I and II trials in acute myeloid leukemia, with QT prolongation as the dose-limiting toxicity. Recently, AC220 has also been shown to be an effective inhibitor of ATP-binding cassette (ABC) proteins ABCB1 (P-glycoprotein) and ABCG2 (breast cancer resistance protein). Quizartinib inhibited transport of fluorescent ABCG2 and ABCB1 substrates in ABCG2- and ABCB1-overexpressing cells in a concentration-dependent manner, from 0.1 to 5µM and from 0.5 to 10µM, respectively, and inhibited-IAAP photolabeling of ABCG2 and ABCB1 with IC(50) values of 0.07 and 3.3µM, respectively.
Supplier:
AMBEED, INC
Description:
6-Iodoquinolin-4-amine, Purity: 95+%, CAS Number: 40107-08-2, Appearance: Powder or crystals, Storage: Keep in dark place, Inert atmosphere, Room temperature, Size: 100mg
Catalog Number:
(101925-626)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 063395-500MG , MDL Number: MFCD08700480
Supplier:
AMBEED, INC
Description:
Bis(4-pyridyl)amine 95%
Supplier:
AMBEED, INC
Description:
1-Methyl-1H-benzimidazol-6-amine 98%
Supplier:
AMBEED, INC
Description:
1-Methylcyclobutan-1-amine hydrochloride 97%
Catalog Number:
(101845-668)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 038519-500MG , MDL Number: MFCD11146772
Supplier:
AMBEED, INC
Description:
2-Isopropylpyridin-3-amine, Purity: 97%, CAS Number: 1369105-90-7, Appearance: White to off-white powder or crystals, Storage: Keep in dark place, Inert atmosphere, Room temperature, Size: 5g
Supplier:
AMBEED, INC
Description:
2-Bromoquinolin-4-amine 97%
Supplier:
AMBEED, INC
Description:
(S)-But-3-yn-2-amine hydrochloride, Purity: 97%, CAS Number: 1414960-66-9, Appearance: White to Yellow Solid, Storage: Inert atmosphere, 2-8 C, Size: 100mg
Supplier:
AMBEED, INC
Description:
Isoindolin-4-amine dihydrochloride, Purity: 97%, CAS Number: 92259-85-3, Appearance: Solid, Storage: Inert atmosphere, Room Temperature, Size: 100MG
Supplier:
AMBEED, INC
Description:
(S)-2-Methoxypropan-1-amine hydrochloride, Purity: 98%, CAS number: 907544-43-8, Appearance: Solid, Storage: Sealed in dry, Room Temperature, Size: 1G
Supplier:
AOB CHEM USA
Description:
4',6-Dimethyl-[1,1'-biphenyl]-3-amine ≥97%
Supplier:
AMBEED, INC
Description:
3-Bromoquinolin-2-amine, Purity: 97%, CAS Number: 36825-31-7, Appearance: Light-yellow to yellow powder or crystal, Storage: Keep in dark place, Inert atmosphere, 2-8C, Size: 1G
Supplier:
AOB CHEM USA
Description:
4'-Methyl-[1,1'-biphenyl]-3-amine ≥97%
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