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Methyl+2-amino-3,5-difluorobenzoate
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Methyl+2-amino-3,5-difluorobenzoate
Catalog Number:
(102114-280)
Supplier:
Novus Biologicals
Description:
Mouse Monoclonal Integrin alpha 4 Antibody (44H6). Tested Applications: Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Frozen. Tested Reactivity: Human.
Supplier:
Shenandoah Biotechnology
Description:
Bone morphogenetic protein 4 (BMP-4) is a member of the bone morphogenetic sub-family (BMP) and functions as a critical element involved in the culture and differentiation of stem cells. Active BMP-4 consists of forming a homodimer or a heterodimer with related BMPs, such as BMP-7.
Supplier:
AMBEED, INC
Description:
2,4-Dichloro-6-(trifluoromethyl)aniline 97%
Catalog Number:
(77528-824)
Supplier:
AFG BIOSCIENCE LLC
Description:
Rat PGF2α (Prostaglandin F2 Alpha) ELISA Kit
Supplier:
Enzo Life Sciences
Description:
Alpha-crystallins composed of alpha A (~20 kDa) and alpha B (~20 kDa) subunits, are major water-soluble proteins accounting for almost 50% of total protein in the mammalian transparent eye lens and they are also found in a variety of other tissues. The two other crystallin families, beta and gamma, are homologous to each other but not to the alpha family or the sHsp's. Alpha-crystallins are also referred to as small heat shock proteins, since they are induced by increased temperature in a variety of organisms. The alpha-crystallins have sequence homology as well as structural and functional similarities with the small Hsp's such as Hsp25/27. Most small heat shock proteins have four common structural and functional features: (i) molecular weight between 12 and 43kDa; (ii) the formation of large oligomeric complexes composed of alphaA-crystallin, alphaB-crystallin and Hsp25/27; (iii) the moderately conserved alpha-crystallin domain in the central region of the protein; and (iv) molecular chaperone activity. The alpha-crystallin domain comprises approximately 90 residues, is bounded by variable N-terminal and C-terminal extensions and is involved in oligomer assembly. Oligomers can reach 800kDa or more and are dynamic, exhibiting subunit exchanges and organizational plasticity, possibly leading to functional diversity. Phosphorylation of serine residues occurs during development and in response to stress, and usually decreases oligomer size. Chaperone activity requires, and is modulated by, oligomerization and is limited to binding unfolded intermediates to prevent irreversible aggregation, although productive release and refolding of denatured proteins requires close cooperation with other chaperones. Other proposed functions include a role in membrane stabilization and modulation of intermediate filament organization during physiological stress and neurodegenerative disease.
Catalog Number:
(10271-318)
Supplier:
Bioss
Description:
In eukaryotes, the phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions, including division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the protein phosphatases. In general, the protein phosphatase (PP) holoenzyme is a trimeric complex composed of a regulatory subunit, a variable subunit, and a catalytic subunit. Four major families of protein phosphatase catalytic subunits have been identified, designated PP1, PP2A, PP2B (calcineurin) and PP2C. An additional protein phosphatase catalytic subunit, PPX (also known as PP4) is a putative member of a novel PP family. The PP2A family comprises subfamily members PP2A Alpha and PP2A Beta. The PP2A catalytic subunit associates with a variety of regulatory subunits. Regulatory subunits include PP2A-A-Alpha and -A-Beta, PP2A-B-Alpha and -B-Beta, PP2A-C-Alpha and -C-Beta, PP2A-B56-Alpha, -B56-Beta, -B56-gamma and -B56-Delta.
Catalog Number:
(220024-772)
Supplier:
R&D Systems
Description:
The Recombinant Mouse CXCL12/SDF-1 alpha Protein from R&D Systems is derived from E. coli. The Recombinant Mouse CXCL12/SDF-1 alpha Protein has been validated for the following applications: Bioactivity.
Catalog Number:
(102869-620)
Supplier:
R&D Systems
Description:
Integrin alpha 11 Affinity Purified Polyclonal Antibody, Goat IgG, Species Reactivity: Human, Immunogen: Chinese hamster ovary cell line CHO-derived recombinant human Integrin alpha 11. Phe23-Pro1141 (Leu524Arg) Accession Number NP_001004439, 100 UG
Supplier:
Tonbo Biosciences
Description:
The 53-6.7 antibody reacts with the 32-34 kDa alpha subunit of mouse CD8, known as CD8a or CD8 alpha. CD8a can form a homodimer (CD8 alpha-alpha), but is more commonly expressed as a heterodimer with a second chain known as CD8b or CD8 beta. CD8 acts as a co-receptor in antigen recognition and subsequent T cell activation that is initiated upon binding of the T cell receptor (TCR) to antigen-bearing MHC Class I molecules. The cytoplasmic domains of CD8 provide binding sites for the tyrosine kinase lck, facilitating intracellular signaling events that lead to T cell activation, development, and cytotoxic effector functions. CD8+ cytotoxic T cells (CTLs) play an important role in inducing cell death of tumor cells, as well as cells infected by virus, bacteria or parasites.
Catalog Number:
(ABCA_AB59461-100UG)
Supplier:
ABCAM INC.
Description:
Anti-p38 alpha/MAPK14 Mouse Monoclonal Antibody [clone: 9F12]
Supplier:
ABCAM INC.
Description:
Anti-Collagen VI alpha 2 Rabbit Monoclonal Antibody [clone: EPR7889(N)]
Catalog Number:
(ABCA_AB99921-50TES)
Supplier:
ABCAM INC.
Description:
Anti-PDGFR alpha Mouse Monoclonal Antibody [clone: 16A1] (PE)
Catalog Number:
(ABCA_AB303055-100U)
Supplier:
ABCAM INC.
Description:
Anti-AMPK alpha 1 Rabbit Monoclonal Antibody [clone: Y365] (HRP)
Catalog Number:
(ABCA_AB237356-100U)
Supplier:
ABCAM INC.
Description:
Anti-TNF alpha Rabbit Monoclonal Antibody [clone: EPR20972] (FITC)
Catalog Number:
(ABCA_AB269282-100T)
Supplier:
ABCAM INC.
Description:
Anti-TNF alpha Mouse Monoclonal Antibody [clone: MAb11] (APC)
Supplier:
ABCAM INC.
Description:
Anti-HNF-4-alpha Rabbit Monoclonal Antibody [clone: EPR19265-130]
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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