N4-Benzoyl-2\\\'-deoxycytidine
Supplier:
Spectrum Chemicals
Description:
4-Aminopyridine, Reagent is an organic compound and is a useful pharmacological tool in studying various potassium conductances in physiology and biophysics. It has also been utilized to manage symptoms of multiple sclerosis. The Reagent grade denotes that this chemical is the highest quality commercially available and that the American Chemical Society has not officially set any specifications for this material. Spectrum Chemical manufactured Reagent grade products meet the toughest regulatory standards for quality and purity.
Catalog Number:
(102514-362)
Supplier:
Adipogen
Description:
The inflammasome is a multiprotein complex that mediates the activation of caspase-1, which promotes, amongst others, the secretion of the proinflammatory cytokines interleukin (IL)-1beta and IL-18. Members of the Nod-like receptor (NLR) family are critical components of the inflammasome that link danger-signals to caspase-1 activation. The NLR member IPAF/NLRC4 senses bacterial flagellin and a conserved type III secretion system (TTSS) rod component. A member of the NLR family, NAIP5 directly and specifically interacts with flagellin, triggers a physical NAIP5-NLRC4 association leading to NLRC4 activation. The related NAIP2 functions analogously to NAIP5, serving as a specific inflammasome receptor for TTSS rod proteins such as Salmonella PrgJ and Burkholderia BsaK.
Supplier:
BeanTown Chemical
Description:
CAS: 623-47-2; EC No: 210-795-8; MDL No: MFCD00009184
UN No: UN3272; Haz Class: 3; Packing Group: III
Liquid; Linear Formula: HC≡CCO2CH2CH3; Molecular Formula: C5H6O2; MW: 98.10
Boiling Point: 120°; Flash point: 25°C (77°F)
Density (g/mL): 0.968; Refractive Index: 1.412
Catalog Number:
(BT122120-100G)
Supplier:
BeanTown Chemical
Description:
CAS: 1892-57-5; EC No: 217-579-2; MDL No: MFCD00044916
UN No: UN2735; Haz Class: 8; Packing Group: III
Liquid; Molecular Formula: C8H17N3; MW: 155.24
Density (g/mL): 0.877; Refractive Index: 1.461
Air Sensitive, Moisture Sensitive
Catalog Number:
(10390-584)
Supplier:
Bioss
Description:
Cytochrome c oxidase subunit I (COI or MTCO1) is one of three mitochondrial DNA (mtDNA) encoded subunits (MTCO1, MTCO2, MTCO3) of respiratory Complex IV. Complex IV is located within the mitochondrial inner membrane and is the third and final enzyme of the electron transport chain of mitochondrial oxidative phosphorylation. Complex IV is composed of 13 polypeptides. Subunits I, II, and III (MTCO1, MTCO2, MTCO3) are encoded by mtDNA while subunits IV, Va, Vb, VIa, VIb, VIc, VIIa, VIIb, VIIc, and VIII are nuclear encoded. Mammalian MTCO1 has 12 membrane-spanning alpha-helices (I to XII).
Catalog Number:
(RL610-709-002)
Supplier:
Rockland Immunochemical
Description:
Suitable for immunomicroscopy and flow cytometry or FACS analysis as well as other antibody based fluorescent assays requiring lot-to-lot consistency.
Catalog Number:
(BT127685-1G)
Supplier:
BeanTown Chemical
Description:
CAS: 40817-08-1; EC No: 255-093-2; MDL No: MFCD00036350
UN No: UN3276; Haz Class: 6.1; Packing Group: III
Liquid; Linear Formula: CH3(CH2)4C6H4C6H4CN; Molecular Formula: C18H19N; MW: 249.35
Boiling Point: 140-150°/0.5 mmHg; Flash point: <gt/>110°C (<gt/>230°F)
Density (g/mL): 1.008; Refractive Index: 1.532
Hygroscopic
Catalog Number:
(10246-022)
Supplier:
Bioss
Description:
Constitutive NADPH oxidase which generates superoxide intracellularly upon formation of a complex with CYBA/p22phox. Regulates signaling cascades probably through phosphatases inhibition. May function as an oxygen sensor regulating the KCNK3/TASK-1 potassium channel and HIF1A activity. May regulate insulin signaling cascade. May play a role in apoptosis, bone resorption and lipolysaccharide-mediated activation of NFKB.
Catalog Number:
(10246-014)
Supplier:
Bioss
Description:
Constitutive NADPH oxidase which generates superoxide intracellularly upon formation of a complex with CYBA/p22phox. Regulates signaling cascades probably through phosphatases inhibition. May function as an oxygen sensor regulating the KCNK3/TASK-1 potassium channel and HIF1A activity. May regulate insulin signaling cascade. May play a role in apoptosis, bone resorption and lipolysaccharide-mediated activation of NFKB.
Supplier:
BeanTown Chemical
Description:
CAS: 12607-70-4; EC No: 240-408-8; MDL No: MFCD00016262; RTECS: QR6260000
UN No: UN3077; Haz Class: 9; Packing Group: III
Powder; Linear Formula: NiCO3·2Ni(OH)2·xH2O; MW: 304.11 (anhydrous)
Catalog Number:
(BT129995-25G)
Supplier:
BeanTown Chemical
Description:
CAS: 12607-70-4; EC No: 240-408-8; MDL No: MFCD00016262; RTECS: QR6260000
UN No: UN3077; Haz Class: 9; Packing Group: III
Powder; Linear Formula: NiCO3·2Ni(OH)2·xH2O; MW: 304.11 (anhydrous)
Catalog Number:
(89270-864)
Supplier:
Genetex
Description:
Rabbit polyclonal antibody to KCNK13 (C-terminal)
Supplier:
BeanTown Chemical
Description:
CAS: 7727-54-0; EC No: 231-786-5; MDL No: MFCD00003390; RTECS: SE0350000
UN No: UN1444; Haz Class: 5.1; Packing Group: III
Powder; Linear Formula: (NH4)2S2O8; MW: 228.20
Moisture Sensitive
Catalog Number:
(75842-962)
Supplier:
BIOGEMS INTERNATIONAL INC.
Description:
The 2.4G2 monoclonal antibody specifically reacts with an epitope on the extracellular domain of the mouse CD16 (Fc γ III) and CD 32 (Fc γ II). CD16 and CD32 are low affinity receptors for the IgG Fc domain and are expressed by B lymphocytes, NK cells, kupffer cells, mast cells, monocytes, macrophages, granulocytes, immature thymocytes, neutrophils, and some activated mature T cells.The 2.4G2 antibody blocks the binding of immunoglobulins to CD16 and CD32, and possibly to Fc γ I receptor.
Catalog Number:
(10239-332)
Supplier:
Bioss
Description:
Gap junction protein that acts as a regulator of bladder capacity. A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph. Negative regulator of bladder functional capacity: acts by enhancing intercellular electrical and chemical transmission, thus sensitizing bladder muscles to cholinergic neural stimuli and causing them to contract (By similarity).
Catalog Number:
(10362-918)
Supplier:
Bioss
Description:
EphB1, previously known as Elk (eph like kinase), is a receptor tyrosine kinase of the highly tissue restricted family of eph proteins. EphB1 and other ephB family members are type 1 membrane spanning proteins, comprised of immunoglobulin, fibronectin type III, and cysteine rich subdomains in the ecto domain, and the single uninterrupted cytoplasmic tyrosine kinase domain upstream of a carboxyterminal sterile alpha motif (SAM) domain. EphB family proteins bind ephrins of the B class. EphB1 is expressed predominately in developing neural structures in embryos, and in vascular epithelium of kidney, and other tissues. Upon binding to alternatively oligomerized ephrin B1, EphB1 signals regulation of cell attachment and cell to cell assembly. Members of this protein family are implicated in neuronal and vascular cell targeting.
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