1-(2-Aminophenyl)piperazine
Catalog Number:
(76121-246)
Supplier:
Bioss
Description:
The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. The protein encoded by this gene is the alpha subunit and belongs to the glycoprotein hormones alpha chain family.
Catalog Number:
(103360-890)
Supplier:
Novus Biologicals
Description:
The p66 alpha Antibody from Novus Biologicals is a rabbit polyclonal antibody to p66 alpha. This antibody reacts with human, mouse, rat. The p66 alpha Antibody has been validated for the following applications: Western Blot, Immunohistochemistry-Paraffin.
Catalog Number:
(102870-754)
Supplier:
R&D Systems
Description:
The Recombinant Human IL-4 R alpha Protein from R&D Systems is derived from Sf 21 (stably transfected). The Recombinant Human IL-4 R alpha Protein has been validated for the following applications: Bioactivity.
Catalog Number:
(75788-860)
Supplier:
Prosci
Description:
Tumor necrosis factor alpha (TNF alpha) is the prototypic ligand of the TNF superfamily. TNF alpha forms a homotrimer and functions by activating two types of receptors TNF-R1 (TNF receptor type 1,p55R) and TNF-R2 (TNF receptor type 2,p75R). TNF alpha is a pleiotropic cytokine that is capable to promote inflammation, to induce apoptotic cell death, and to inhibit tumorigenesis and viral replication. TNF alpha is a potent lymphoid factor that exerts cytotoxic effects on a wide range of tumor cells and certain other target cells.
Catalog Number:
(103310-766)
Supplier:
Novus Biologicals
Description:
The SRPR alpha Antibody from Novus Biologicals is a mouse polyclonal antibody to SRPR alpha. This antibody reacts with human. The SRPR alpha Antibody has been validated for the following applications: Western Blot.
Catalog Number:
(103636-264)
Supplier:
Sino Biological
Description:
Produced in rabbits immunized with purified, recombinant Human IkB alpha / NFKBIA (rh IkB alpha / NFKBIA; Catalog#12045-H07E; Phe2-Leu317; NP_065390.1). IkB alpha / NFKBIA specific IgG was purified by Human IkB alpha / NFKBIA affinity chromatography.
Supplier:
AMBEED, INC
Description:
(S)-(+)-α-Methoxyphenylacetic acid 98%
Catalog Number:
(103323-916)
Supplier:
Novus Biologicals
Description:
The Choline kinase alpha Antibody from Novus Biologicals is a mouse polyclonal antibody to Choline kinase alpha. This antibody reacts with human. The Choline kinase alpha Antibody has been validated for the following applications: Western Blot.
Catalog Number:
(10294-548)
Supplier:
Bioss
Description:
Heterotrimeric G proteins function to relay information from cell surface receptors to intracellular effectors. Each of a very broad range of receptors specifically detects an extracellular stimulus (a photon, pheromone, odorant, hormone or neurotransmitter) while the effectors (i.e., adenyl cyclase), which act to generate one or more intracellular messengers, are less numerous. In mammals, G protein Alpha, Beta and Gamma polypeptides are encoded by at least 16, 4 and 7 genes, respectively. Most interest in G proteins has been focused on their Alpha subunits, since these proteins bind and hydrolyze GTP and most obviously regulate the activity of the best studied effectors. Four distinct classes of G Alpha subunits have been identified; these include G Alpha s, G Alpha i, G Alpha q and G Alpha 12/13. The two members of the fourth class of G Alpha subunit proteins, G Alpha 12 and G Alpha 13, are insensitive to ADP-ribosylation by pertussis toxin, share 67% identity with each other and less than 45% identity with other G Alpha subunits and are widely expressed in a broad range of tissues.
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 041645-500MG , MDL Number: MFCD02682504
Catalog Number:
(103283-078)
Supplier:
Novus Biologicals
Description:
The Protein Kinase A regulatory subunit I alpha Antibody from Novus Biologicals is a rabbit polyclonal antibody to Protein Kinase A regulatory subunit I alpha. This antibody reacts with human. The Protein Kinase A regulatory subunit I alpha Antibody has been validated for the following applications: Western Blot, Simple Western, Immunohistochemistry, Immunohistochemistry-Paraffin.
Catalog Number:
(102164-792)
Supplier:
Novus Biologicals
Description:
The Proteasome 20S alpha 2 Antibody from Novus Biologicals is a rabbit polyclonal antibody to Proteasome 20S alpha 2. This antibody reacts with human. The Proteasome 20S alpha 2 Antibody has been validated for the following applications: Western Blot, Immunohistochemistry, Immunocytochemistry / Immunofluorescence, Immunohistochemistry-Paraffin.
Catalog Number:
(102137-952)
Supplier:
Novus Biologicals
Description:
Alpha Actinin 4 Overexpression Lysate (Adult Normal)
Catalog Number:
(102142-450)
Supplier:
Novus Biologicals
Description:
alpha Endosulfine Overexpression Lysate (Adult Normal)
Catalog Number:
(75791-026)
Supplier:
Prosci
Description:
Tumor Necrosis Factor- alpha (TNF- alpha) is secreted by macrophages, monocytes, neutrophils, T-cells, and NK-cells following stimulation by bacterial LPS. Cells expressing CD4 secrete TNF- alpha while cells that express CD8 secrete little or no TNF- alpha. Synthesis of TNF- alpha can be induced by many different stimuli including interferons, IL2, and GM-CSF. The clinical use of the potent anti-tumor activity of TNF- alpha has been limited by the proinflammatory side effects such as fever, dose-limiting hypotension, hepatotoxicity, intravascular thrombosis, and hemorrhage. Designing clinically applicable TNF- alpha mutants with low systemic toxicity has been of intense pharmacological interest. Human TNF- alpha that binds to murine TNF-R55 but not murine TNF-R7, exhibits retained anti-tumor activity and reduced systemic toxicity in mice compared with murine TNF- alpha, which binds to both murine TNF receptors. Based on these results, many TNF- alpha mutants that selectively bind to TNF-R55 have been designed. These mutants displayed cytotoxic activities on tumor cell lines in vitro and have exhibited lower systemic toxicity in vivo. Recombinant Human TNF- alpha High Active Mutant differs from the wild-type by amino acid subsitution of amino acids 1-7 with Arg8, Lys9, Arg10 and Phe157. This mutant form has been shown to have increased activity with less inflammatory side effects in vivo.
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