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2-Formylphenylboronic+acid
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2-Formylphenylboronic+acid
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
Sodium tetrachloropalladate(II) (∼36% Pd)
Catalog Number:
(EM1.08816.9025)
Supplier:
MilliporeSigma
Description:
EMSURE® (formerly GR) is a premium grade of reagents for wet chemical analysis, adhering to ACS, ISO, and/or Reag. Ph.Eur quality specifications.
Catalog Number:
(77439-836)
Supplier:
Bioss
Description:
ATF6 is a transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. It binds DNA on the 5'-CCAC[GA]-3'half of the ER stress response element (ERSE) (5'-CCAAT-N(9)-CCAC[GA]-3') and of ERSE II (5'-ATTGG-N-CCACG-3'). Binding to ERSE requires binding of NF-Y to ERSE. ATF6 could also be involved in activation of transcription by the serum response factor. ATF6 exists as a homodimer and heterodimer with ATF6 beta. The dimer interacts with the nuclear transcription factor Y (NF-Y) trimer through direct binding to NF-Y subunit C (NF-YC). It also interacts with the transcription factors GTF2I, YY1 and SRF. Under ER stress the cleaved N-terminal cytoplasmic domain translocates into the nucleus. The basic domain of ATF6 functions as a nuclear localization signal and the basic leucine zipper domain is sufficient for association with the NF-Y trimer and binding to ERSE. During the unfolded protein response an approximately 50 kDa fragment containing the cytoplasmic transcription factor domain is released by proteolysis. The cleavage seems to be performed sequentially by site 1 and site 2 proteases. ATF6 is N glycosylated, phosphorylated in vitro by MAPK14/P38MAPK and belongs to the bZIP family.
Catalog Number:
(102534-252)
Supplier:
Matrix Scientific
Description:
MF=C26H24CL2NIP2 MW=528.04 CAS=14647-23-5 MDL=MFCD00013313 5G
Supplier:
Strem Chemicals Inc
Description:
Chloro{(R)-(-)-1,13-bis(diphenylphosphino)-7,8-dihydro-6H-dibenzo[f,h][1,5]dioxonin}(p-cymene)ruthenium(II) chloride
Supplier:
Strem Chemicals Inc
Description:
CAS #: 13820-53-6. Size: 10g.
Supplier:
BeanTown Chemical
Description:
CAS: 3518-65-8; EC No: 222-526-1; MDL No: MFCD00014727; RTECS: PB2800000
UN No: UN3265; Haz Class: 8; Packing Group: II
Liquid; Linear Formula: ClCH2SO2Cl; Molecular Formula: CH2Cl2O2S; MW: 149.00
Density (g/mL): 1.64
Moisture Sensitive
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
Bis(acetonitrile)palladium(II) dichloride 99%
Catalog Number:
(101780-926)
Supplier:
AMBEED, INC
Description:
Chlorohydridotris(triphenylphosphine)ruthenium(II) toluene adduct 98%
Catalog Number:
(101443-448)
Supplier:
Rigaku Reagents
Description:
Use our stock solutions directly or as a component in solutions you create in your own lab. We prepare our stock solutions using high quality raw materials, ASTM Type 1 water, and sterile packaging. Our stock solutions are intended for Research and Development Use Only.
Supplier:
AMBEED, INC
Description:
cis-[2,2'-Bis(diphenylphosphino)-1,1'-binaphthyl](2-methylphenyl)nickel(II) chloride, Purity: 98%, CAS Number: 1594113-05-9, Appearance: Solid, Storage: Keep in dark place, Inert atmosphere, 2-8C, Size: 100MG
Supplier:
AMBEED, INC
Description:
Bis(benzonitrile)palladium chloride, Purity: 99% Pd 27.7%, CAS number: 14220-64-5, Appearance: Pale-yellow to yellow red to yellow-brown to red-brown or orange powder or crytals, Storage: Keep in dark place, Inert atmosphere, Room temperature, Size: 250MG
Catalog Number:
(10239-068)
Supplier:
Bioss
Description:
Transmembrane serine/threonine kinase forming with the TGF-beta type II serine/threonine kinase receptor, TGFBR2, the non-promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinogenesis. The formation of the receptor complex composed of 2 TGFBR1 and 2 TGFBR2 molecules symmetrically bound to the cytokine dimer results in the phosphorylation and the activation of TGFBR1 by the constitutively active TGFBR2. Activated TGFBR1 phosphorylates SMAD2 which dissociates from the receptor and interacts with SMAD4. The SMAD2-SMAD4 complex is subsequently translocated to the nucleus where it modulates the transcription of the TGF-beta-regulated genes. This constitutes the canonical SMAD-dependent TGF-beta signaling cascade. Also involved in non-canonical, SMAD-independent TGF-beta signaling pathways. For instance, TGFBR1 induces TRAF6 autoubiquitination which in turn results in MAP3K7 ubiquitination and activation to trigger apoptosis. Also regulates epithelial to mesenchymal transition through a SMAD-independent signaling pathway through PARD6A phosphorylation and activation.
Supplier:
BeanTown Chemical
Description:
CAS: 98-58-8; EC No: 202-683-2; MDL No: MFCD00007437
UN No: UN3261; Haz Class: 8; Packing Group: II
Crystalline/Powder; Molecular Formula: C6H4BrClO2S; MW: 255.52
Melting Point: 73-75°; Boiling Point: 153°/15 mmHg
Moisture Sensitive
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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