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Catalog Number:
(10275-814)
Supplier:
Bioss
Description:
Voltage-gated K+ channels in the plasma membrane are important regulators of electrical signaling, controlling the repolarization and the frequency of action potentials in neurons, muscles and other excitable cells. KCNT2 is a 1,135 amino acid multi-pass transmembrane protein belonging to the potassium channel family (calcium-activated subfamily) of proteins. KCNT2 produces rapidly activating outward rectifier potassium currents in reponse to high intracellular sodium and chloride levels. Its channel activity is inhibited by ATP, inhalation anesthetics, such as isoflourane, and upon stimulation of G-protein coupled receptors, such as mAChR M1 and GluR-1. There are four isoforms of KCNT2 that are produced as a result of alternative splicing events.
Supplier:
BeanTown Chemical
Description:
CAS: 13450-88-9; EC No: 236-609-5; MDL No: MFCD00016100
UN No: UN3260; Haz Class: 8; Packing Group: II
Crystalline; Linear Formula: GaBr3; MW: 309.45
Melting Point: 122°; Boiling Point: 279°
Density (g/mL): 3.69
Moisture Sensitive
Supplier:
Thermo Scientific
Description:
Adapter for 6.5 ml round bottom Blood Collection Tube, HIGHConic * III Rotor and 8 x 50 ml conical rotor, 1 place/adapter
Catalog Number:
(10332-594)
Supplier:
Bioss
Description:
Membrane Receptors Transforming growth factor beta is a multifunctional cytokine known to modulate several tissue development and repair processes, including cell differentiation, cell cycle progression, cellular migration, adhesion, and extracellular matrix production. There are 3 forms encoded by separate genes TGFB1, TGFB2, and TGFB3. The diverse effects of TGF beta are mediated by the TGF beta receptors and cell surface binding proteins. In addition to type I TGF beta receptor (TGFBR1) and type II (TFGBR2), type III (TGF beta III receptor) has been identified. It is a glycoprotein that binds TGF beta and exists in both a membrane bound and a soluble form. It may serve as a receptor accessory molecule in both the TGF beta and fibroblast growth factor systems. TGF beta III receptor lacks a recognizable signaling domain and has no clearly defined role in TGF beta signaling. Endothelial cells undergoing epithelial mesenchymal transformation express TGF beta III receptor, and TGF beta III receptor specific antisera inhibits mesenchyme formation and migration. Misexpression of TGF beta III receptor in nontransforming ventricular endothelial cells conferrs transformation in response to TGFB2. These results support a model where TGF beta III receptor localizes transformation in the heart and plays an essential, nonredundant role in TGF beta signaling. TGF beta III receptor, or beta glycan, can function as an inhibin coreceptor with ActRII. TGF beta III receptor binds inhibin with high affinity and enhances binding in cells coexpressing ActRII and TGF beta III receptor. Inhibin forms crosslinked complexes with both recombinant and endogenously expressed TGF beta III receptor and ActRII. TGF beta III receptor confers inhibin sensitivity to cell lines that otherwise respond poorly to this hormone.
Catalog Number:
(10332-596)
Supplier:
Bioss
Description:
Membrane Receptors Transforming growth factor beta is a multifunctional cytokine known to modulate several tissue development and repair processes, including cell differentiation, cell cycle progression, cellular migration, adhesion, and extracellular matrix production. There are 3 forms encoded by separate genes TGFB1, TGFB2, and TGFB3. The diverse effects of TGF beta are mediated by the TGF beta receptors and cell surface binding proteins. In addition to type I TGF beta receptor (TGFBR1) and type II (TFGBR2), type III (TGF beta III receptor) has been identified. It is a glycoprotein that binds TGF beta and exists in both a membrane bound and a soluble form. It may serve as a receptor accessory molecule in both the TGF beta and fibroblast growth factor systems. TGF beta III receptor lacks a recognizable signaling domain and has no clearly defined role in TGF beta signaling. Endothelial cells undergoing epithelial mesenchymal transformation express TGF beta III receptor, and TGF beta III receptor specific antisera inhibits mesenchyme formation and migration. Misexpression of TGF beta III receptor in nontransforming ventricular endothelial cells conferrs transformation in response to TGFB2. These results support a model where TGF beta III receptor localizes transformation in the heart and plays an essential, nonredundant role in TGF beta signaling. TGF beta III receptor, or beta glycan, can function as an inhibin coreceptor with ActRII. TGF beta III receptor binds inhibin with high affinity and enhances binding in cells coexpressing ActRII and TGF beta III receptor. Inhibin forms crosslinked complexes with both recombinant and endogenously expressed TGF beta III receptor and ActRII. TGF beta III receptor confers inhibin sensitivity to cell lines that otherwise respond poorly to this hormone.
Supplier:
ALADDIN SCIENTIFIC
Description:
Ammonium tetrachloroaurate hydrate ≥99.99% (metals basis), PrimorTrace™
Supplier:
Strem Chemicals Inc
Description:
CAS #: 7783-51-9. Size: 5g.
Catalog Number:
(76816-694)
Supplier:
AMBEED, INC
Description:
2-Bromo-1,1-dimethoxyethane, Purity: 98% contains 0.5% potassium carbonate as stabilizer, CAS Number: 7252-83-7, Appearance: Colorless Liquid, Storage: Keep in dark place, Inert atmosphere, 2-8C, Size: 10G
Catalog Number:
(102221-490)
Supplier:
Novus Biologicals
Description:
The Collagen III alpha 1/COL3A1 Native Protein has been validated for the following applications: Western Blot, ELISA, Immunohistochemistry.
Catalog Number:
(10783-442)
Supplier:
CHI Scientific
Description:
Kit PrimaCell* 4, Mouse Brain OptiTDS* 4: Tissue Dissociation System, A mixture ofcollagenase I, collagenase III, collagenase III, and collagenase IV
Catalog Number:
(10786-498)
Supplier:
CHI Scientific
Description:
Kit PrimaCell* Rat Aorta OptiTDS*, Tissue Dissociation System, A mixture of collagenase I, collagenase III, collagenase III and collagenase IV.
Catalog Number:
(103617-484)
Supplier:
Sino Biological
Description:
This antibody was obtained from a rabbit immunized with purified, recombinant Human Carbonic Anhydrase III / CA3 (rh Carbonic Anhydrase III / CA3; Catalog#10503-H08E; NP_005172.1; Met1-Lys260).
Catalog Number:
(10168-558)
Supplier:
Genetex
Description:
Mouse monoclonal antibody [M17-P5-F11] to Sodium/Potassium ATPase beta
Catalog Number:
(10349-068)
Supplier:
Bioss
Description:
Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. It is activated by internal ATP and probably plays an important role in potassium homeostasis. The encoded protein has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Mutations in this gene have been associated with antenatal Bartter syndrome, which is characterized by salt wasting, hypokalemic alkalosis, hypercalciuria, and low blood pressure. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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