3-(2-Chlorophenyl)-1-propene
Catalog Number:
(101921-686)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 061293-500MG , MDL Number: MFCD00173815
Catalog Number:
(101820-468)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 025545-500MG , MDL Number: MFCD02093411
Supplier:
BeanTown Chemical
Description:
CAS: 113-92-8; EC No: 205-054-0; MDL No: MFCD00069225; RTECS: US6504000
UN No: UN2811 ; Haz Class: 6.1; Packing Group: III
Solid; Molecular Formula: C16H19ClN2·C4H4O4; MW: 390.86
Melting Point: 130-135°
Catalog Number:
(76884-978)
Supplier:
AOB CHEM USA
Description:
2,3-Difluoro-6-chlorophenylboronic acid ≥97%
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 046293-5G , MDL Number: MFCD03701150
Supplier:
Thermo Scientific Chemicals
Description:
N-Fmoc-4-chloro-L-phenylalanine, 98%
Catalog Number:
(101916-220)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 058893-1G , MDL Number: MFCD09702433
Catalog Number:
(10118-474)
Supplier:
Restek
Description:
Contains: Aramite (140-57-8); Bis(2-chloroethyl)ether (111-44-4); Bis(2-chloroethoxy)methane (111-91-1); 4-Bromophenyl phenyl ether (101-55-3); Chlorobenzilate (510-15-6); 2-Chloronaphthalene (91-58-7); 4-Chlorophenyl phenyl ether (7005-72-3); 1,2-Dichlorobenzene (95-50-1); 1,3-Dichlorobenzene (541-73-1); 1,4-Dichlorobenzene (106-46-7); 1,3-Dinitrobenzene (99-65-0); Hexachlorobenzene (118-74-1); Hexachlorobutadiene (87-68-3); Hexachlorocyclopentadiene (77-47-4); Hexachloroethane (67-72-1); Hexachloropropene (1888-71-7); Isodrin (465-73-6); Kepone (143-50-0); 2,2'-Oxybis(1-chloropropane) (108-60-1); Pentachlorobenzene (608-93-5); Pentachloronitrobenzene (quintozene) (82-68-8); 1,2,4,5-Tetrachlorobenzene (95-94-3); 1,2,4-Trichlorobenzene (120-82-1)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 044094-5G , MDL Number: MFCD00172032
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 043661-1G , MDL Number: MFCD01314630
Supplier:
Matrix Scientific
Description:
MF=C8H10Cln MW=155.63 Cas=13078-80-3 MDL=MFCD00008185 5G
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
Carbonylcyanide-3-chlorophenylhydrazone 98%
Catalog Number:
(102667-660)
Supplier:
Matrix Scientific
Description:
3-Amino-5-methylthio-1H-1,2,4-triazole
Supplier:
Adipogen
Description:
(+)-JQ1 is a potent, high affinity, selective BET bromodomain inhibitor (IC(50) values of 17.7, 32.6, 76.9 and 12942nM respectively for BRD2 (N-terminal (N)), BRD4 (C-terminal (C)), BRD4 (N) and CREBBP, respectively. In binding assays, (+)-JQ1 binds competitive with acetyl lysine to BRD4 bromodomain 1 (Kd=50nM) and and BRD4 bromodomain 2 (Kd=90 nM). May be a useful chemical probe to investigate the role of BET bromodomains in the transcriptional regulation of oncogenesis. (+)-JQ1 exhibited strong dose- and time-dependent inhibition of BRDT, a bromodomain-containing protein highly enriched in testis. BRDT is involved in chromatin remodeling and is essential for healthy sperm development. (+)-JQ1 appears to block that function and causes a decrease in sperm viability, being examined as a potential male contraceptive. Inhibitor of inflammation and bone destruction.
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