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4-(tert-Butyl)phenyl+trifluoromethanesulfonate
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4-(tert-Butyl)phenyl+trifluoromethanesulfonate
Supplier:
BeanTown Chemical
Description:
CAS: 5329-14-6; EC No: 226-218-8; MDL No: MFCD00011603; RTECS: W05950000
UN No: UN2967; Haz Class: 8; Packing Group: III
Crystalline; Linear Formula: NH2SO3H; MW: 97.09
Melting Point: 215-225° (decomposes)
Supplier:
BeanTown Chemical
Description:
CAS: 58-08-2; EC No: 200-362-1; MDL No: MFCD00005758; RTECS: EV6475000
UN No: UN1544; Haz Class: 6.1; Packing Group: III
Powder; Molecular Formula: C8H10N4O2; MW: 194.19
Melting Point: 234-236°
Catalog Number:
(76084-194)
Supplier:
Bioss
Description:
Receptor tyrosine kinase involved in the development and the maturation of the central and peripheral nervous systems through regulation of proliferation, differentiation and survival of sympathetic and nervous neurons. High affinity receptor for NGF which is its primary ligand, it can also bind and be activated by NTF3/neurotrophin-3. However, NTF3 only supports axonal extension through NTRK1 but has no effect on neuron survival. Upon dimeric NGF ligand-binding, undergoes homodimerization, autophosphorylation and activation. Recruits, phosphorylates and/or activates several downstream effectors including SHC1, FRS2, SH2B1, SH2B2 and PLCG1 that regulate distinct overlapping signaling cascades driving cell survival and differentiation. Through SHC1 and FRS2 activates a GRB2-Ras-MAPK cascade that regulates cell differentiation and survival. Through PLCG1 controls NF-Kappa-B activation and the transcription of genes involved in cell survival. Through SHC1 and SH2B1 controls a Ras-PI3 kinase-AKT1 signaling cascade that is also regulating survival. In absence of ligand and activation, may promote cell death, making the survival of neurons dependent on trophic factors. Isoform TrkA-III is resistant to NGF, constitutively activates AKT1 and NF-kappa-B and is unable to activate the Ras-MAPK signaling cascade. Antagonizes the anti-proliferative NGF-NTRK1 signaling that promotes neuronal precursors differentiation. Isoform TrkA-III promotes angiogenesis and has oncogenic activity when overexpressed.
Catalog Number:
(10320-192)
Supplier:
Bioss
Description:
This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene is expressed in some human cancer cell lines and has been implicated in carcinogenesis.
Catalog Number:
(10426-880)
Supplier:
Bioss
Description:
KCNK9 or TASK-3 (TWIK-related Acid sensitive K+ channel) is a member of the potassium channel family of proteins that contain two-pore domain and four transmembrane domains. These channels are characterized as leak K+ channels that are sensitive to changes in the extracellular pH. The physiological functions of TASK channels are largely unknown; it has been proposed that they may be involved in the regulation of breathing, aldosterone secretion and anesthetic-mediated neuronal activity. They were found to act in neurons' membrane potential and in resting K+ currents.
Supplier:
Tonbo Biosciences
Description:
The 2.4G2 antibody is specific for a common epitope found in the extracellular regions of mouse Fc-receptors Fc-gamma II (CD32) and Fc-gamma III (CD16). As these are receptors for the Fc portion of mouse IgG, they may also bind laboratory antibody preparations and products used in a variety of cell analysis protocols such as flow cytometry, immunohistochemistry and functional cell assays. The 2.4G2 antibody is therefore widely used as a pre-treatment reagent to block binding of specific antibodies of interest, e.g. fluorescently conjugated antibodies, to Fc receptors via their Fc domains and contributing to “non-specific” staining.
Supplier:
BeanTown Chemical
Description:
CAS: 7784-27-2; EC No: 236-751-8; MDL No: MFCD00003419; RTECS: BD1050000
UN No: UN1438; Haz Class: 5.1; Packing Group: III
Crystalline; Linear Formula: Al(NO3)3·9H2O ; MW: 375.13
Melting Point: 73°
Hygroscopic
Supplier:
BeanTown Chemical
Description:
CAS: 143-27-1; EC No: 205-596-8; MDL No: MFCD00008158; RTECS: ML9100000
UN No: UN3259; Haz Class: 8; Packing Group: III
Crystalline; Linear Formula: CH3(CH2)15NH2; Molecular Formula: C16H35N; MW: 241.46
Melting Point: 43-45°; Boiling Point: 330°; Flash point: 140°C (284°F)
Density (g/mL): 0.813
Supplier:
BeanTown Chemical
Description:
CAS: 31469-15-5; MDL No: MFCD00010232
UN No: UN1993; Haz Class: 3; Packing Group: III
Liquid; Molecular Formula: C8H18O2Si; MW: 174.31
Boiling Point: 35°/15 mmHg; Flash point: 30°C (86°F)
Density (g/mL): 0.858; Refractive Index: 1.415
Moisture Sensitive
Supplier:
BeanTown Chemical
Description:
CAS: 119020-01-8; MDL No: MFCD03419257
UN No: UN2735; Haz Class: 8; Packing Group: III
Liquid; Molecular Formula: C10H20N2O2 ; MW: 200.28
Catalog Number:
(75931-388)
Supplier:
Rockland Immunochemical
Description:
PTPRD (Protein tyrosine phosphatase receptor type D) is a member of the protein tyrosine phosphatase (PTP) family that plays diverse roles during development including cell growth, differentiation, mitotic cycle and oncogenic transformation. PTPRD contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains. The extracellular region of PTPRD is composed of three Ig-like and eight fibronectin type III-like domains (1,3). PTPRD interacts with PPFIA1-3 and is a tumor suppressor on chromosome 9p that is involved in the development of glioblastoma multiforme (GBMs) and multiple human cancers.
Supplier:
BeanTown Chemical
Description:
CAS: 2052-01-9; EC No: 218-139-2; MDL No: MFCD00004168
UN No: UN3261; Haz Class: 8; Packing Group: III
Powder; Molecular Formula: C4H7BrO2 ; MW: 167.00
Melting Point: 44-47°; Boiling Point: 198-200°; Flash point: <gt/>110°C (<gt/>230°F)
Catalog Number:
(10051-934)
Supplier:
Enzo Life Sciences
Description:
Dopamine is the predominant catecholamine neurotransmitter in the mammalian brain, where it regulates locomotor, emotional, memory, and dietary intake functions, as well as peripheral roles such as hormone secretion and renal function. Dopamine receptors (D1-D5) are members of the seven transmembrane domain containing GPCR family, and are the target of several anti-psychosis and anti-Parkinsonian drugs. The D2, D3, and D4 receptors signal via coupling of Gi/Go alpha G-protein subunits to inhibit adenylyl cyclase activity and modulate cellular potassium and calcium ion channel conductance. Expression of the D2 receptor is found primarily in the brain (striatum, olfactory tubercle, and nucleus accumbens) and in the anterior and intermediate lobes of the pituitary.
Supplier:
Epredia
Description:
Epredia™ Gill Hematoxylin 1, 2, and 3 are rapid progressive hematoxylins that are widely known and respected in the Histology and Cytology fields.
Supplier:
BeanTown Chemical
Description:
CAS: 1779-51-7; EC No: 217-219-4; MDL No: MFCD00011855; RTECS: TA1855200
UN No: UN3464; Haz Class: 6.1; Packing Group: III
Crystalline; Linear Formula: (C6H5)3P(Br)CH2CH2CH2CH3; Molecular Formula: C22H24BrP; MW: 339.30
Melting Point: 240-243°
Hygroscopic
Supplier:
BeanTown Chemical
Description:
CAS: 12230-71-6; EC No: 241-234-5; MDL No: MFCD00149152; RTECS: CQ9200000
UN No: UN3262; Haz Class: 8; Packing Group: III
Crystalline; Linear Formula: Ba(OH)2·8H2O; MW: 315.46
Melting Point: 78°
Air Sensitive , Hygroscopic
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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