Ethyl+2-(2-chloroethoxy)acetate
Supplier:
MP Biomedicals
Description:
Dimethyl sulfoxide is a dipolar, aprotic solvent. Has been shown to accelerate strand renaturation (1-10% concentration) and is believed to give the nucleic acid thermal stability against depurination. By heating the solid form to approximately 30 °C, the product can be melted without harming it's stability.
Supplier:
MP Biomedicals
Description:
Cell permeable fungal toxin that disrupts contractile microfilaments by inhibiting actin polymerization. This, in turn, induces DNA fragmentation, inhibits cell division, and disrupts many cell processes. Inhibits glucose transport.
One of a group of fungal metabolites that interfere with a wide variety of cellular movements. Useful tool for characterizing some of the polymerization properties of actin, and in studies on cytokinesis. Probe for the two hexose-transport systems in rat L6 myoblasts.
Catalog Number:
(IC15123925)
Supplier:
MP Biomedicals
Description:
Sodium 1-heptanesulfonate is a commonly used ion pairing reagent for HPLC, including analyses of peptides and proteins. It has also been used in high performance capillary electrophoresis analysis of peptides.
Supplier:
MP Biomedicals
Description:
Sucrose is a non-reducing disaccharide composed of glucose and fructose linked via their anomeric carbons. It is obtained commercially from sugarcane, sugar beet, and other plants and used extensively as a food and a sweetener. The mixture of glucose and fructose is known as "invert sugar."
Supplier:
Adipogen
Description:
Antibiotic. Shows antiviral, antifungal and antitumor properties. Immunosuppressive drug used to prevent rejection in organ transplantation, rheumatoid arthritis, and psoriasis. Potent reversible inhibitor of inosine-5'-monophosphate dehydrogenase (IMPDH), leading to depletion of GMP and interruption of the de novo synthesis of purine nucleotides necessary for B and T lymphocyte proliferation. Inhibits the type II IMPDH isoform (IMPDH-2) 5-fold more potently compared to type I isoform. Inhibits RNA and DNA synthesis. Inducible nitric oxide synthase (iNOS/NOS II) inhibitor. Apoptosis and necrosis inducer. Novel type of inhibitor against RNA guanylyltransferases. Inhibits TNF-alpha-stimulated MAPK/NF-kappaB and ROS generation.
Catalog Number:
(21432-348)
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Supplier:
Adipogen
Description:
Immune response modifier. Potent antitumor and antiviral compound. Stimulates antibody secretion and cytokine production. Used as adjuvant to increase the effectiveness of vaccines. Potent and selective synthetic ligand for Toll-like receptor 7 (TLR7) in mouse and for TLR7 and TLR8 in human. Activates immune cells via the TLR7/TLR8 MyD88-dependent signaling pathway and leads to the induction of NF-kappaB. NLRP3/NALP3 inflammasome activator, independent of TLRs and RIG-I. Upregulator of the opioid growth factor receptor. Used in the treatment of skin lesions such as herpes simplex virus.
Catalog Number:
(EM1.04595.0005)
Supplier:
Adipogen
Description:
Antibiotic. Potent and highly selective Ca2+ ionophore. Commonly used to modify intracellular calcium levels to study calcium transport across biological membranes and to calibrate fluorescent Ca2+ indicators. Ionomycin also transports Pb2+ and some other divalent cations, as well as several lanthanide series trivalent cations at efficiencies that are greater than or equal to those for Ca2+. Apoptosis inducer. Induces apoptotic neuronal degeneration in embryonic cortical neurons and cell cycle arrest at G1 phase and induces central demyelination. Used to stimulate the intracellular production of the cytokines, interferon, perforin, IL-2 and IL-4 usually in conjunction with PMA. ADAM10 agonist. Potent inducer of shedding CXCL16. TREK-1 channels inhibitor. PPARgamma ligand with a unique binding mode. Shows effective glucose-lowering activity in a mouse model of diabetes.
Supplier:
Adipogen
Description:
Rhodamine 6G is a highly fluorescent hydrophilic pH-sensitive dye. It is often used as a tracer dye within water to determine the rate and direction of flow and transport. Rhodamine dyes are used extensively in biotechnology applications such as fluorescence microscopy, flow cytometry, fluorescence correlation spectroscopy and ELISA. The dye has a remarkably high photostability and high fluorescence quantum yield. Used as a laser dye and potential mitochondrial probe. The lasing range of the dye is 555 to 585 nm with a maximum at 566 nm. Useful in Pgp efflux assays and has been used to characterize kinetics of MRP1-mediated efflux. Spectral data: lambdaex 528 nm| lambdaem 551 nm (in MeOH).
Supplier:
Adipogen
Description:
Synthetic analog of Lovastatin. Potent competitive HMG-CoA reductase inhibitor. Anti-hypercholesterolemic agent. Cholesterol/isoprenoid biosynthesis inhibitor. Blocks the production of mevalonate, a critical compound in the production of cholesterol and isoprenoids. Inhibits the isoprenylation of Ras and Rho family GTPases. Smooth muscle cell proliferation inhibitor. Anti-adhesive, immunomodulatory and anti-inflammatory compound. Proteasome modulator. Stimulates bone formation. Apoptosis inducer. Anticancer compound. Increases cellular resistance to anticancer agents such as doxorubicin and etoposides. Suppresses ICAM-1-LFA-1 interactions, which blocks virus replication and infection. Anti-hypertensive agent. Suppresses TNF-induced NF-kappaB activation.
Catalog Number:
(76724-104)
Supplier:
AMBEED, INC
Description:
Ethyl-3-(pyridin-2-ylamino)propanoate 95%
Catalog Number:
(102991-280)
Supplier:
Adipogen
Description:
CD14/TLR4 antagonist. Inhibitor of sterile inflammation. Synthetic TLR4/CD14 ligand with TLR4 modulating activities in vitro, and conferring protection against TLR4/CD14-mediated tissue damage and inflammation in vivo. Useful to explore CD14- dependent and TLR4-independent pathways and TLR4 activation by endogenous ligands (e.g. hyaluronic acid oligosaccharides, oxLDL, HMGB1) in sterile inflammation. Shown to inhibit neuropathic pain, secondary necrosis of acute drug-induced liver failure and vascular inflammation, and abdominal aortic aneurysm by blocking non-hematopoietic TLR4 signaling. Useful tool, where inhibition of sterile (auto-) inflammation is desired, without compromising TLR4’s key role in the defense of pathogens.
Catalog Number:
(75835-544)
Supplier:
Restek
Description:
The mix consists of acetonitrile, acrylonitrile, allyl chloride , benzene, bromobenzene, bromochloromethane, bromodichloromethane, bromoform, n-butylbenzene, sec-butylbenzene, tert-butylbenzene, carbon disulfide, carbon tetrachloride, chlorobenzene, 2-chloroethanol, chloroform, chloroprene , 2-chlorotoluene, 4-chlorotoluene, dibromochloromethane, 1,2-dibromo-3-chloropropane , 1,2-dibromoethane , dibromomethane, 1,2-dichlorobenzene, 1,3-dichlorobenzene, 1,4-dichlorobenzene, cis-1,4-dichloro-2-butene, trans-1,4-dichloro-2-butene, 1,1-dichloroethane, 1,2-dichloroethane, 1,1-dichloroethene, cis-1,2-dichloroethene, trans-1,2-dichloroethene, 1,2-dichloropropane, 1,3-dichloropropane, 2,2-dichloropropane, 1,1-dichloropropene, cis-1,3-dichloropropene, trans-1,3-dichloropropene, diethyl ether , 1,4-dioxane, ethylbenzene, ethyl methacrylate, hexachloro-1,3-butadiene, iodomethane , isobutyl alcohol , isopropylbenzene , 4-isopropyl toluene , methacrylonitrile, methyl acrylate, methyl methacrylate, methylene chloride , naphthalene, nitrobenzene, 2-nitropropane, propionitrile, n-propylbenzene, styrene, 1,1,1,2-tetrachloroethane, 1,1,2,2-tetrachloroethane, tetrachloroethene, tetrahydrofuran, toluene, 1,2,3-trichlorobenzene, 1,1,1-trichloroethane, 1,1,2-trichloroethane, trichloroethene, 1,2,3-trichloropropane, 1,1,2-trichlorotrifluororethane , 1,2,4-trimethylbenzene, 1,3,5-trimethylbenzene, m-xylene, o-xylene, p-xylene.
Supplier:
MP Biomedicals
Description:
Protein purification reagent Triethanolamine acts as an organic additive in the grinding of cement clinker and as a complexing agent for aluminum ions in aqueous solutions.
It is used as an emulsifier and a surfactant. It finds application in common products like dishwashing liquids, general cleaners, hand cleaners, shaving cream, metalworking fluids, liquid laundry detergents, paints and printing inks. It is used for the neutralization of fatty acids and adjusting buffer pH as well as utilized to dissolve oils. It acts as an effective complexing agent in electroless plating. Further, it is used in hair care products like hair dyes and wave sets.
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