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Ishikawa\'s reagent
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Ishikawa\'s reagent
Supplier:
Adipogen
Description:
Tamatinib effectively inhibits BCR signaling in vivo, resulting in reduced proliferation and survival of the malignant B cells and significantly prolonged survival of the treated animals.
Supplier:
AMBEED, INC
Description:
5-Amino-1-(2-hydroxyethyl)pyrazole, Purity: 98%, CAS Number: 73616-27-0, Appearance: Form: Crystal - Powder/Colour: White - Pale reddish yellow - Yellow, Storage: Keep in dark place, Sealed in dry, 2-8 C, Size: 25g
Supplier:
Adipogen
Description:
CP-724714 is an oral, selective and potent ErbB-2 (HER2) kinase inhibitor with an IC(50) of 10 nM. It has <gt/>640-fold selectivity for ErbB-2 (HER2) over EGFR, InsR, IRG-1R, PDGFR, VEGFR2, Abl, Src, c-Met.
Supplier:
Adipogen
Description:
MLN0128 is a potent and selective mTOR inhibitor with an IC(50) of 1nM; <gt/>200-fold less potent to class I PI3K isoforms, superior in blocking mTORC1/2 and sensitive to pro-invasion genes (vs Rapamycin).
Catalog Number:
(80053-496)
Supplier:
MilliporeSigma
Description:
Olomoucine is a purine derivative that acts as a potent and selective inhibitor of p34cdc2/Cyclin B (IC50=7µM) and related kinases, including p33cdk2/Cyclin A (IC50=7µM), p33cdk2/Cyclin E (IC50=7µM), p33cdk5/p35 (IC50=3µM), and p44 MAP kinase (IC50=25µM)
Supplier:
Adipogen
Description:
CGI1746 was identified as a selective and potent ATP-competitive BTK inhibitor with an IC(50) of 1.9nM. It is specific for BTK, with around 1000-fold selectivity over Tec and Src family kinases.
Supplier:
Adipogen
Description:
Selective N- and P/Q-type Ca2+-channel agonist. These Ca2+-channels regulate transmitter release in synapses. Potential lead compound for a variety of disorders that result in neuromuscular weakness.
Supplier:
Adipogen
Description:
Lapatinib is an ATP-competitive epidermal growth factor receptor (EGFR) and HER2/neu (ErbB-2) dual tyrosine kinase inhibitor, with IC(50) values of 10.8 and 9.2nM respectively. It is an orally active drug for treatment of breast cancer and other solid tumors.
Supplier:
TCI America
Description:
CAS Number: 23364-44-5
MDL Number: MFCD00074959 Molecular Formula: C14H15NO Molecular Weight: 213.28 Purity/Analysis Method: >99.0% (GC,T) Form: Crystal Melting point (°C): 144 Specific rotation [a]20/D: 7 deg (C=0.6, EtOH)
Catalog Number:
(10282-054)
Supplier:
Bioss
Description:
ADH6 (alcohol dehydrogenase 6), also known as ADH-5, is a 368 amino acid member of the class V zinc-containing alcohol dehydrogenase family. This family of enzymes functions to metabolize a wide variety of substrates such as retinol, hydroxysteroids, ethanol, aliphatic alcohols and lipid peroxidation products. Localized to the cytoplasm and expressed in the stomach and liver, ADH6 catalyzes the reversible oxidation of alcohols to their corresponding aldehydes or ketones and is able to bind two zinc ions as cofactors. ADH6 contains a glucocorticoid response element upstream of its 5' UTR which is thought to be a steroid binding site, suggesting that expression of ADH6 may be under hormonal control. Multiple isoforms of ADH6 exist due to alternative splicing events.
Catalog Number:
(TCT0255-500ML)
Supplier:
Adipogen
Description:
NVP-BGJ398 inhibits FGFR-WT, FGFR2-WT, FGFR3-K650E, FGFR3-S249C and FGFR4-WT with IC(50) values of 4.6, 4.9, 5, 5 and 168nM, respectively.
Supplier:
Adipogen
Description:
BMS-599626 is an orally bioavailable, highly selective and potent pan-HER kinase inhibitor. It inhibits HER1 and HER2 with IC(50) values of 20 and 30nM, respectively.
Catalog Number:
(IC0520181180)
Supplier:
MP Biomedicals
Description:
1,2-Butylene Oxide is a hydrogen chloride acceptor in chlorocarbons, e.g. trichloroethylene. It is also a valuable intermediate in many syntheses, e.g. in the production of butylene glycol, 2-amino-1-butanol, and polyols for polyurethane plastics. Other products obtained from it are nonionic surfactants that are used as textile and dyeing auxiliaries, crude oil deemulsifiers, etc. It is also used as a solvent for natural and synthetic resins and in polymerization.
Physical Appearance: Off-White Powder Solubility: Soluble in Chloroform, Dimetyl Sulfoxide and Ethanol
Catalog Number:
(TS11392-0010)
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
Diethanolamine 99%
Supplier:
Adipogen
Description:
BI-D1870 is a small molecule, specific inhibitor of p90 RSK (ribosomal S6 kinase) isoforms RSK1, RSK2, RSK3 and RSK4, both in vitro and in vivo, with IC(50)s are 31nM, 24nM, 18nM, 15nM, respectively. It shows a 10- to 100-fold selectivity for RSK over MST2, GSK-3beta, MARK3, CK1 and Aurora B.
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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