N\\\\\\\\\\\\\\\'-[1-Cyclobutylaminopropylidene]hydrazinecarboxyl
Supplier:
AMBEED, INC
Description:
(S)-1-(4-Bromophenyl)ethanol, Purity: 98%, CAS Number: 100760-04-1, Appearance: Form: liquid Colour: colourless, Storage: Sealed in dry, Room Temperature, Size: 100mg
Supplier:
ALADDIN SCIENTIFIC
Description:
AK-7 is a selective cell- and brain-permeable SIRT2 inhibitor, with an IC50 of 15.5 μM.
Catalog Number:
(10388-164)
Supplier:
Bioss
Description:
Ubiquitin like proteins fall into two classes: the first class, ubiquitin-like modifiers (UBLs) function as modifiers in a manner analogous to that of ubiquitin. Examples of UBLs are SUMO, Rub1 (also called Nedd8), Apg12 and Hub1. Proteins of the second class include Parkin, RAD23 and DSK2, are designated ubiquitin domain proteins (UDPs). These proteins contain domains that are related to ubiquitin but are otherwise unrelated to each other. In contrast to UBLs, UDPs are not proteolytically processed or conjugated to other proteins. Rub1 and the corresponding human homolog NEDD8 are activated by the E1 ubiquitin activating enzyme UBA2, that forms isopeptide linkages between thio esters. NEDD8 shows 80% homology to ubiquitin. The best known targets of Rub1 modification are members of the cullin family. Cullins are subunits of an E3 ubiquitin ligase complex called the Skp1 /Cul1/Cdc53 F box (SCF). The SCF promotes transfer of ubiquitin from a ubiquitin conjugating enzyme (E2) to the target protein. Rub1 modification may regulate SCF function or localization.
Supplier:
Thermo Scientific Chemicals
Description:
2-(4-Bromophenyl)-5,5-dimethyl-1,3,2-dioxaborinane. Grade: 98+. Melting Point C109-111*. Boiling Point C: NA. C11H14BBrO2. 183677-71-6. MOISTURE SENSITIVE
Supplier:
Matrix Scientific
Description:
3'-Bromo-2,2-dimethylpropiophenone ≥97%
Catalog Number:
(TCB2889-5G)
Supplier:
TCI America
Description:
CAS Number: 244205-40-1
MDL Number: MFCD01114672 Molecular Formula: C6H6BBrO2 Molecular Weight: 200.83 Form: Crystal Color: White Melting point (°C): 110
Supplier:
AMBEED, INC
Description:
3-(Azepan-1-ylsulfonyl)-N-(3-bromophenyl)benzamide, Purity: 98%, CAS Number: 420831-40-9, Appearance: Solid, Storage: Keep in dark place, Inert atmosphere, Room temperature, Size: 50mg
Supplier:
AMBEED, INC
Description:
(3-Bromophenyl)methanamine, Purity: 98%, CAS Number: 10269-01-9, Appearance: Liquid, Storage: Keep in dark place, Inert atmosphere, 2-8 deg C, Size: 10g
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 043185-1G , MDL Number: MFCD02260778
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 007401-100G , MDL Number: MFCD00239386
Supplier:
AMBEED, INC
Description:
1-Bromo-4-pentylbenzene 98%
Supplier:
Thermo Scientific Chemicals
Description:
4-Bromophenylboronic acid. Grade: 98+, Melting Point C282-286*. Boiling Point C: NA. C6H6BBrO2. 5467-74-3. IRRITANT
Catalog Number:
(10388-162)
Supplier:
Bioss
Description:
Ubiquitin like proteins fall into two classes: the first class, ubiquitin-like modifiers (UBLs) function as modifiers in a manner analogous to that of ubiquitin. Examples of UBLs are SUMO, Rub1 (also called Nedd8), Apg12 and Hub1. Proteins of the second class include Parkin, RAD23 and DSK2, are designated ubiquitin domain proteins (UDPs). These proteins contain domains that are related to ubiquitin but are otherwise unrelated to each other. In contrast to UBLs, UDPs are not proteolytically processed or conjugated to other proteins. Rub1 and the corresponding human homolog NEDD8 are activated by the E1 ubiquitin activating enzyme UBA2, that forms isopeptide linkages between thio esters. NEDD8 shows 80% homology to ubiquitin. The best known targets of Rub1 modification are members of the cullin family. Cullins are subunits of an E3 ubiquitin ligase complex called the Skp1 /Cul1/Cdc53 F box (SCF). The SCF promotes transfer of ubiquitin from a ubiquitin conjugating enzyme (E2) to the target protein. Rub1 modification may regulate SCF function or localization.
Catalog Number:
(76109-022)
Supplier:
Bioss
Description:
The G protein-coupled receptor TGR5 is a 330-amino acid protein that is almost universally expressed in human tissues including heart, skeletal muscle, spleen, kidney, liver, small intestine, placenta, and leukocytes, but not in brain, colon (without mucosa), thymus, or lung. TGR5 is sensitive to bile acids and responds through a significant mechanism that coordinates energy homeostasis. Bile acids activate mitogen-activated protein (MAP) kinase pathways, specifically induce TGR5 internalization, promote an increase of guanosine 5'-O-3-thio-triphosphate binding in membrane fractions, and cause rapid intracellular cAMP production. Bile acids also provoke TGR5 to suppress macrophage functions. TGR5-controlled signaling pathways may be good candidates for drug targets to treat common metabolic diseases, such as obesity, type II diabetes, hyperlipidemia, and atherosclerosis.
Supplier:
AMBEED, INC
Description:
3-Bromothioanisole 95%
Supplier:
AMBEED, INC
Description:
3-(4-Bromophenyl)acrylic acid, Purity: 98%, CAS Number: 1200-07-3, Appearance: Form: Crystal - Powder/Colour: White - Very pale yellow red, Storage: Sealed in dry, Room Temperature, Size: 10g
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