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4-Amino-3-bromobenzoic+acid
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4-Amino-3-bromobenzoic+acid
Catalog Number:
(10072-610)
Supplier:
Prosci
Description:
BMPs (Bone Morphogenetic Proteins) belong to the TGF-beta superfamily of structurally related signaling proteins. BMP-2 is a potent osteoinductive cytokine, capable of inducing bone and cartilage formation in association with osteoconductive carriers such as collagen and synthetic hydroxyapatite. In addition to its osteogenic activity, BMP-2 plays an important role in cardiac morphogenesis and is expressed in a variety of tissues including lung, spleen, brain, liver, prostate ovary and small intestine. The functional form of BMP-2 is a 26 kDa protein composed of two identical 114 amino acid polypeptide chains linked by a single disulfide bond. Each BMP-2 monomer is expressed as the C-terminal part of a precursor polypeptide, which also contains a 23 amino acid signal sequence for secretion, and a 259 amino acid propeptide. After dimerization of this precursor, the covalent bonds between the propeptide (which is also a disulfide-linked homodimer) and the mature BMP-2 ligand are cleaved by a furin-type protease. Recombinant human BMP-2 is a 26.0 kDa homodimeric protein consisting of two 115 amino acid polypeptide chains.
Catalog Number:
(10289-588)
Supplier:
Bioss
Description:
Excitatory Amino Acid Transporters (EAATs) are membrane-bound proteins that are localized in glial cells and pre-synaptic glutamatergic nerve endings. EAATs transport the excitatory neurotransmitters L-glutamate and D-aspartate, a process that is essential for terminating the postsynaptic action of glutamate. The re-uptake of amino acid neurotransmitters by EAAT proteins has been shown to protect neurons from excitotoxicity, which is caused by the accumulation of amino acid neurotransmitters. EAAT4 is an aspartate/glutamate transporter that is expressed predominantly in the cerebellum. The transport activity encoded by EAAT4 has high apparent affinity for L-aspartate and L-glutamate, and has a pharmacologic profile consistent with previously described cerebellar transport activities. EAAT5 is a glutamate transporter coupled to a chloride conductance which is expressed primarily in retina. Although EAAT5 shares the structural homologies of the EAAT family, a novel feature of the EAAT5 sequence is a carboxy-terminal motif previously identified in N-ethyl-D-aspartate receptors and potassium channels and shown to confer interactions with a family of synaptic proteins that promote ion channel clustering.
Supplier:
PeproTech, Inc.
Description:
IL-17E is a disulfide-linked homodimer of two 145 amino acid polypeptide chains. It belongs to the IL-17 family of structurally-related cytokines that share a highly conserved C-terminal region, but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family, IL-17A through IL-17F, are secreted as homodimers. IL-17E stimulates secretion of IL-8, and induces activation of the transcription factor NF-κB in cells that express the IL-17BR receptor. Recombinant Human IL-17E is a 33.8 kDa disulfide-linked homodimer of two 146 amino acid polypeptide chains.
Catalog Number:
(10109-020)
Supplier:
Prosci
Description:
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2D2 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase.SLC38A4 is found predominantly in liver and transports both cationic and neutral amino acids. The transport of cationic amino acids by SLC38A4 is Na (+) and pH independent, while the transport of neutral amino acids is Na (+) and pH dependent (Hatanaka et al., 2001).
Catalog Number:
(95041-214)
Supplier:
HiMedia
Description:
Lactalbumin Hydrolysate is rich in essential amino acids and can be successfully used to supplement tissue culture media where viral vaccines are produced.
Catalog Number:
(10072-760)
Supplier:
Prosci
Description:
GDF-11 is a myostatin-homologous protein that acts as an inhibitor of nerve tissue growth. GDF-11 has been shown to suppress neurogenesis through a myostatin-like pathway, which involves arrest of progenitor cell-cycle in the G1 phase. Similarities between myostatin and GDF-11, which are 90% identical in their amino acid sequence, suggests that the regulatory mechanisms responsible for maintaining proper tissue size during neural and muscular development might be the same. Recombinant human GDF-11 is a 25.0 kDa disulfide-linked homodimer containing two 109 amino acid polypeptide chains. It is highly homologous to myostatin/GDF-8 sharing 90% amino-acid sequence identity.
Catalog Number:
(10112-246)
Supplier:
Prosci
Description:
Polyclonal, Host: Goat, Species: Human, Mouse, Immunogen: Annexin antibody was raised against a 15 amino acid synthetic peptide near the N-Terminus of Annexin, Application: ELISA, WB
Catalog Number:
(10112-634)
Supplier:
Prosci
Description:
Polyclonal, Host: Goat, Species: Mouse, Rat, Immunogen: FEM1C antibody was raised against a 14 amino acid synthetic peptide near the C-Terminus of FEM1C, Application: ELISA, WB
Catalog Number:
(10117-032)
Supplier:
Prosci
Description:
Polyclonal; Host: Goat; Species Reactiviy: Human; Immunogen: MARCH7 antibody was raised against an 11 amino acid synthetic peptide near the internal region of 40975; Application: ELISA
Catalog Number:
(10112-374)
Supplier:
Prosci
Description:
Polyclonal, Host: Goat, Species: Human, Immunogen: AKAP9 antibody was raised against a 12 amino acid synthetic peptide near the C-Terminus of AKAP9, Application: ELISA, WB, IHC
Catalog Number:
(10112-262)
Supplier:
Prosci
Description:
Polyclonal, Host: Goat, Species: Human, Immunogen: FTCD antibody was raised against a 15 amino acid synthetic peptide near the internal region of FTCD, Application: ELISA, WB
Catalog Number:
(103007-788)
Supplier:
Anaspec Inc
Description:
This peptide is derived from rat angiotensinogen amino acid residues 1-14. It is a synthetic renin substrate.
Sequence: DRVYIHPFHLLYYS MW: 1823.1 Da % Peak area by HPLC: 95 Storage condition: -20°C
Catalog Number:
(10082-280)
Supplier:
Proteintech
Description:
APH, (APEH, acylpeptide hydrolase), which catalyzes the hydrolysis of the terminal acetylated amino acid preferentially from small acetylated peptides. The acylpeptide hydrolase is a homotetrameric protein of 300 kDa with each subunit consisting of 732 amino acid residues. A range of molecular masses have been reported for APH by previous investigators, including 80 kD, 75 kD and 69 kD. This antibody can recognize at least 2 isoforms of APH.
Supplier:
Enzo Life Sciences
Description:
Produced in <i>E. coli.</i> Contains 207 amino acids.
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 020677-5G , MDL Number: MFCD01566303
Catalog Number:
(100277-262)
Supplier:
Indofine Chemical Company
Description:
Rare Organics & BioChemicals 1gm BOC-D-Bta-OH 321.4 Room temperature.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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