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2-(Piperidin-4-ylidene)acetic+acid+hydrochloride
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2-(Piperidin-4-ylidene)acetic+acid+hydrochloride
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
2,4-Dichlorobenzylamine 98%
Supplier:
AMBEED, INC
Description:
PHA-665752 99%
Catalog Number:
(76916-578)
Supplier:
AOB CHEM USA
Description:
4-Bromo-2,3-dichloroaniline ≥97%
Catalog Number:
(TCD2425-005G)
Supplier:
TCI America
Description:
CAS Number: 38594-42-2
MDL Number: MFCD00238581 Molecular Formula: C7H6Cl2O Molecular Weight: 177.02 Purity/Analysis Method: >98.0% (GC) Form: Crystal Melting point (°C): 86
Catalog Number:
(77303-108)
Supplier:
AMBEED, INC
Description:
Miconazole 98%
Supplier:
ALADDIN SCIENTIFIC
Description:
Aripiprazole is a human 5-HT1A receptor partial agonist with a Ki of 4.2 nMA selective dopamine D2-receptor antagonist showing autoreceptor agonist activity.Aripiprazole has been used to study behavioral and neurochemical effects of aripiprazole treatment in juvenile spontaneously hypertensive rats (SHR), a model for attention deficit hyperactivity disorder (ADHD).Aripiprazole has been used to study its effect on mammary tumorigenesis, mediated by retrovirus delivery of receptor tyrosine-protein kinase 2 or HRas proto-oncogene, GTPase or by transgenic expression of Wnt-1 (proto-oncoprotein). It has also been used to study its behavioral and neurochemical effects in juvenile spontaneously hypertensive rats.
Supplier:
Adipogen
Description:
Kinases, such as LIM kinase 1 (LIMK1) and LIM kinase 2 (LIMK2), have been identified as participating in signal pathways affecting actin dynamics by deactivating cofilin. Over expression of LMK1 has been found in invasive breast and prostate cancer cell lines and suppression of LIMK 2 expression has been found to limit migration of human fibrosarcoma cells. Thus, the inhibition of LIMK1 and/or LIMK2 enzymes have been suggested as targets for treating cancer, including reduction or prevention of metastasis. BMS-5 is a potent inhibitor of the LIM kinase. It has IC(50) values of 7nM and 8nM for LIMK1 and LIMK2 respectively. LIMK1/2 activity was measured via TCA precipitation assay using a biotinylated ADF (actin depolymization factor) as the protein substrate and the kinase domains of LIMK1 and LIMK2 as the enzyme sources in the presence of 1µM ATP.
Supplier:
Matrix Scientific
Description:
2',3'-Dichloro-2,2,2-trifluoroacetophenone ≥97%
Supplier:
Matrix Scientific
Description:
MF=C9H9CL2NO2 MW=234.08 CAS=52794-99-7 MDL=MFCD00191203 10G
Supplier:
TCI America
Description:
CAS Number: 65277-42-1
MDL Number: MFCD00058579 Molecular Formula: C26H28Cl2N4O4 Molecular Weight: 531.43 Purity/Analysis Method: >98.0% (HPLC,T) Form: Crystal Melting point (°C): 150 Storage Temperature: 0-10°C
Supplier:
Thermo Scientific Chemicals
Description:
Inhibits cytochrome P450-dependent 14-alpha-demethylase
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