1-(4-Bromo-2-isopropylphenyl)ethanone
Catalog Number:
(10294-644)
Supplier:
Bioss
Description:
Heterotrimeric G proteins function to relay information from cell surface receptors to intracellular effectors (1). Each of a very broad range of receptors specifically detects an extracellular stimulus (a photon, pheromone, odorant, hormone or neurotransmitter) while the effectors (i.e., adenylyl cyclase), which act to generate one or more intracellular messengers, are less numerous. In mammals, G protein alpha, Beta and Gamma polypeptides are encoded by at least 16, 4 and 7 genes, respectively (2-5). Most interest in G proteins has been focused on their a subunits, since these proteins bind and hydrolyze GTP and most obviously regulate the activity of the best studied effectors. Four distinct classes of G alpha subunits have been identified; these include Gs, Gi, Gq and Ga 12/13 (3,4). The Gi class comprises all the known a subunits that are susceptible to pertussis toxin modifications, including Ga i-1, Ga i-2, Ga i-3, Ga o, Ga t1, Ga t2, Ga z and Ga gust (4). Of these, the three Ga i subtypes function to open atrial potassium channels (6). Ga 16 is a member of the Gq subfamily and is expressed specifically in hematopoietic cells (7).
Catalog Number:
(RL609-9002)
Supplier:
Rockland Immunochemical
Description:
Secondary Chicken Anti-IgG (H&L) Reacts with Human
Catalog Number:
(RL609-9202)
Supplier:
Rockland Immunochemical
Description:
Secondary Chicken Anti-IgG (H&L) Reacts with Human
Catalog Number:
(RL603-109-002)
Supplier:
Rockland Immunochemical
Description:
Secondary Goat Anti-IgY Reacts with Chicken
Catalog Number:
(RL610-606-002)
Supplier:
Rockland Immunochemical
Description:
Secondary Sheep Anti-IgG (H&L) Reacts with Mouse
Catalog Number:
(RL-613-4102)
Supplier:
Rockland Immunochemical
Description:
Secondary Rabbit Anti-IgG (H&L) Reacts with Sheep (Ovine)
Catalog Number:
(RL603-101-126)
Supplier:
Rockland Immunochemical
Description:
Secondary Goat Anti-IgY Reacts with Chicken
Catalog Number:
(RL114-4107)
Supplier:
Rockland Immunochemical
Description:
Secondary Rabbit Anti-IgM mu chain Reacts with Pig (Swine, Porcine)
Catalog Number:
(RL606-4103)
Supplier:
Rockland Immunochemical
Description:
Secondary Rabbit Anti-IgG F(c) Reacts with Guinea Pig
Catalog Number:
(100504-076)
Supplier:
Electron Microscopy Sciences
Description:
A metal stain for ultra thin sections.
![]()
Catalog Number:
(10671-192)
Supplier:
Bioss
Description:
Voltage-gated K+ channels in the plasma membrane control the repolarization and the frequency of action potentials in neurons, muscles and other excitable cells. The KV gene family encodes more than 30 proteins that comprise the subunits of the K+ channels, and they vary in their gating and permeation properties, subcellular distribution and expression patterns. Functional KV channels assemble as tetramers consisting of pore-forming å subunits (KV), which include the KV1, KV2, KV3 and KV4 proteins, and accessory or KV-subunits that modify the gating properties of the coexpressed KV subunits. KV∫, also known as KCNAB1 (potassium voltage-gated channel, shaker-related subfamily, beta member 1), is a 419 amino acid accessory K+ channel protein that exists as three alternatively spliced isoforms and regulates the activity of the pore-forming å subunit. It is expressed in brain, with highest levels detected in caudate nucleus, hippocampus and thalamus.
Catalog Number:
(10289-592)
Supplier:
Bioss
Description:
Excitatory Amino Acid Transporters (EAATs) are membrane-bound proteins that are localized in glial cells and pre-synaptic glutamatergic nerve endings. EAATs transport the excitatory neurotransmitters L-glutamate and D-aspartate, a process that is essential for terminating the postsynaptic action of glutamate. The re-uptake of amino acid neurotransmitters by EAAT proteins has been shown to protect neurons from excitotoxicity, which is caused by the accumulation of amino acid neurotransmitters. EAAT4 is an aspartate/glutamate transporter that is expressed predominantly in the cerebellum. The transport activity encoded by EAAT4 has high apparent affinity for L-aspartate and L-glutamate, and has a pharmacologic profile consistent with previously described cerebellar transport activities. EAAT5 is a glutamate transporter coupled to a chloride conductance which is expressed primarily in retina. Although EAAT5 shares the structural homologies of the EAAT family, a novel feature of the EAAT5 sequence is a carboxy-terminal motif previously identified in N-ethyl-D-aspartate receptors and potassium channels and shown to confer interactions with a family of synaptic proteins that promote ion channel clustering.
Catalog Number:
(RL612-9102)
Supplier:
Rockland Immunochemical
Description:
Secondary Chicken Anti-IgG (H&L) Reacts with Rat
Catalog Number:
(76010-868)
Supplier:
Prosci
Description:
The function of this protein remains unknown.
Catalog Number:
(11277-338)
Supplier:
Mettler Toledo
Description:
Ion Selective half-cells electrodes consist of two elements, a universal shaft and an ion-specific membrane module.
![]()
Catalog Number:
(10220-716)
Supplier:
MP Biomedicals
Description:
Double antibiotic solution containing 5,000 units/mL of penicillin and 5,000 µg/mL of streptomycin.
Inquire for Price
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
![]()
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
![]()
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organization. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
|
|||||||||