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N\'-[1-Cyclobutylaminopropylidene]hydrazinecarboxylic+acid-tert-b
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N\'-[1-Cyclobutylaminopropylidene]hydrazinecarboxylic+acid-tert-b
Catalog Number:
(76010-496)
Supplier:
Prosci
Description:
The protein encoded by this gene is the medium chain of the trans-Golgi network clathrin-associated protein complex AP-1. The other components of this complex are beta-prime-adaptin, gamma-adaptin, and the small chain AP1S1. This complex is located at the Golgi vesicle and links clathrin to receptors in coated vesicles. These vesicles are involved in endocytosis and Golgi processing. Alternatively spliced transcript variants encoding distinct protein isoforms have been found for this gene. [provided by RefSeq].
Catalog Number:
(490015-798)
Supplier:
GVS FILTER TECHNOLOGY
Description:
Supported Nitrocellulose (MCE) membranes.
Supplier:
Matrix Scientific
Description:
Rel-(3R, 4R)-4-Benzylamino-1-[Tert-Butoxycarbonyl]-3-Fluoropiperidine, MF=C17H25FN2O2, MW=308.40, CAS=211108-52-0, 250MG
Supplier:
Thermo Scientific Chemicals
Description:
Bis(tri-o-tolylphosphine)palladium(II) dichloride ≥98%
Catalog Number:
(103223-432)
Supplier:
Novus Biologicals
Description:
TGN38, Polyclonal Antibody, Host: Sheep, Species reactivity: Rat, Isotype: IgG, Immunogen: Human embryonic kidney cell line HEK293-derived recombinant rat TGN38 Leu18-Ser303, synonyms: trans-golgi network protein 2, Application: WB, ICC, Size: 25UG
Catalog Number:
(77267-718)
Supplier:
AMBEED, INC
Description:
(E)-Methyl 4-methylpent-2-enoate, Purity: 96%, CAS Number: 20515-15-5, Appearance: Liquid, Storage: Sealed in dry, Room Temperature, Size: 1g
Catalog Number:
(10749-234)
Supplier:
Prosci
Description:
The phosphofurin acidic cluster sorting protein 1 (PACS1), belongs to the PACS family of cytosolic connector proteins that localize different membrane proteins to the trans-Golgi network (TGN). Mutations in PACS1 cause defects in cranial-neural crest migration during early development, leading to a recognizable intellectual disability syndrome. PACS1, along with the related protein PACS2, also plays a role in HIV-1 Nef-mediated downregulation of cell surface MHC-I molecules to the TGN, thereby enabling HIV-1 to escape immune surveillance.
Catalog Number:
(89279-670)
Supplier:
Genetex
Description:
rabbit polyclonal antibody to Glucose transporter 5
Catalog Number:
(10234-268)
Supplier:
Bioss
Description:
Neurobeachin binds to type II regulatory subunits of protein kinase A and anchors/targets them to the membrane. It may anchor the kinase to cytoskeletal and/or organelle-associated proteins. Neurobeachin, is also a neuron-specific multidomain protein of 327 kDa with a high-affinity binding site for the type II regulatory subunit of protein kinase A. Neurobeachin is peripherally associated with pleomorphic tubulovesicular endomembranes near the trans sides of Golgi stacks and throughout the cell body and cell processes. It is also found in a subpopulation of synapses, where it is concentrated at the postsynaptic plasma membrane.
Catalog Number:
(TCT2284-1G)
Supplier:
TCI America
Description:
CAS Number: 3559-74-8
Molecular Formula: C8H14Si Molecular Weight: 138.29 Purity/Analysis Method: >97.0% (GC) Form: Clear Liquid Color: Colorless Boiling point (°C): 140 Melting point (°C): -19 Flash Point (°C): 29 Specific Gravity (20/20): 0.85 Storage Temperature: 0-10°C
Catalog Number:
(10069-094)
Supplier:
Prosci
Description:
Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) is a member of the hnRNP A/B family of related RNA binding proteins that bind pre-mRNA and are involved in the processing, metabolism and transport of nuclear pre-mRNA transcripts. hnRNP A1 regulates the alternative splicing of c-Src, c-H-Ras and modifies initiation of translation of the fibroblast growth factor 2 mRNA. hnRNP A1 expression level is elevated in many cancers; knockdown of hnRNP A1 leads to apoptosis in various cancer cells. Although predominantly nuclear, hnRNP A1 is continually transported from the nucleus to the cytoplasm where it disassociates from mRNA and is rapidly re-imported into the nucleus. hnRNP A1 binds to cis-acting repressive sequences (CRS) of HIV-1 to influence HIV-1 production. HIV-1 enhances hnRNP A1 expression and promotes the relocalization of hnRNP A1 to the cytoplasm ,
Catalog Number:
(10813-750)
Supplier:
Prosci
Description:
Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins; one of which is CD45. Preferentially binds to alpha2,6-linked sialic acid. The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface. Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules.
Catalog Number:
(10424-758)
Supplier:
Bioss
Description:
Contactin 2 is a neuronal cell adhesion molecule (CAM) that influences the formation of axon connections in the developing nervous system. Contactin 2 is a member of the immunoglobulin superfamily (IgSF) and contains a glycosylphosphatidylinositol-anchor, six immunogobulin (Ig)-like and four Fibronectin type III (FNIII)-like domains. Contactin 2 is expressed predominantly during neural development on the cell membrane of axons in nerve fiber tracts in order to guide commissural axons without promoting their growth. Contactin 2 binds with NgCAM in the plane of the same membrane (cis-binding). The Contactin 2 heterophilic (Contactin 2/NgCAM and Contactin 2/NrCAM) binding sites are localized to the first four Ig domains. The Contactin 2 homophilic (Contactin 2/Contactin 2) binding site is localized to the FNIII domain.
Supplier:
AMBEED, INC
Description:
Bis(tri-o-tolylphosphine)palladium(II) dichloride 98%
Catalog Number:
(75929-436)
Supplier:
Rockland Immunochemical
Description:
KHDC1 family members are K-homology (KH) domain-containing RNA binding proteins that are involved in various aspects of RNA metabolism, ranging from transcription to RNA splicing, transportation, translation, and stability (1). KHDC1 is highly expressed in oocytes and interacts with cytoplasmic polyadenylation element-binding protein 1 (CPEB1), a key translational regulator controlling the polyA length of mRNAs (2,3). KHDC1 functions as a global translational repressor and induces apoptosis through an ER-dependent signaling pathway and that the C-terminal putative trans-membrane motif (TMM) is critical for its activities (3,4).
Catalog Number:
(103265-390)
Supplier:
Southern Biotechnology
Description:
CD33 is a 67 kDa type I transmembrane glycoprotein and a member of the sialoadhesin family of cell surface receptors. It is absent from pluripotent stem cells but appears on myelomonocytic precursors after CD34. It then continues to be expressed on both the myeloid and monocyte lineages. While it has been reported that CD33 can function as a sialic acid-dependent cell adhesion molecule, cells expressing CD33 require desialylation before they can bind cells bearing the appropriate sialoglycoconjugates. This suggests that inhibitory cis interactions may regulate or block any adhesion function.
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