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5-Methyl-2-heptene+(cis-+and+trans-+mixture)
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5-Methyl-2-heptene+(cis-+and+trans-+mixture)
Catalog Number:
(76011-674)
Supplier:
Prosci
Description:
RBL2 is a key regulator of entry into cell division. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransferases SUV420H1 and SUV420H2, leading to epigenetic transcriptional repression. Controls histone H4 'Lys-20' trimethylation. Probably acts as a transcription repressor by recruiting chromatin-modifying enzymes to promoters. Potent inhibitor of E2F-mediated trans-activation, associates preferentially with E2F5. Binds to cyclins A and E. Binds to and may be involved in the transforming capacity of the adenovirus E1A protein. RBL2 may act as a tumor suppressor.
Supplier:
Thermo Scientific Chemicals
Description:
Protein staining following gel electrophoresis
Catalog Number:
(10234-978)
Supplier:
Bioss
Description:
Histones are highly conserved proteins that serve as the structural scaffold for the organization of nuclear DNA into chromatin. The four core histones, H2A, H2B, H3, and H4, assemble into an octamer (2 molecules of each). Subsequently, 146 base pairs of DNA are wrapped around the octamer, forming a nucleosome, the basic subunit of chromatin. Histone modifications regulate DNA transcription, repair, recombination, and replication. The most commonly studied modifications are acetylation, phosphorylation, methylation, and ubiquitination. These modifications can alter local chromatin architecture, or recruit trans-acting factors that recognize specific histone modifications (the "histone code" hypothesis). Trimethylation of histone H3 on Lys9 (H3K9me3) is one of the most highly studied epigenetic marks. H3K9me3 functions in the repression of euchromatic genes, and in epigenetic control of heterochromatin assembly, most likely via acting as a recognition motif for the binding of chromatin-associated proteins, such as Swi6 or HP1Alpha/Beta. The enzymes responsible for H3K9me3 formation are SUV39H1 and SUV39H2.
Catalog Number:
(BDH2000-5GLMS)
Supplier:
TCI America
Description:
Form: Clear Liquid
Color: Colorless Boiling point (°C): 251 Melting point (°C): 14 Flash Point (°C): 137 Specific Gravity (20/20): 1.22 Storage Temperature: 0-10°C
Catalog Number:
(95041-470)
Supplier:
VWR International
Description:
Laboratory grade quality suitable for procedures in Histology
Catalog Number:
(EM1.01922.0100)
Supplier:
MilliporeSigma
Catalog Number:
(TS460400010)
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
Methyl palmitoleate 99% analytical standard for GC
Catalog Number:
(95043-422)
Supplier:
G-Biosciences
Description:
G-Biosciences' Coomassie Brilliant Blue (CBB) G-250 and R-250 Stain are based on a colloidal Coomassie stain. CBB G-250 and R-250 stain proteins with high band visibility. The staining of gels with CBB G-250 and R-250 allows the examination of protein bands even during the staining process.
Supplier:
MP Biomedicals
Description:
Brefeldin A reversibly inhibits the intracellular translocation of proteins in eukaryotes, e.g., during transport of proteins to the cell surface for secretion or expression. It has been reported to block the response of cultured cells to cholera toxin. BFA inhibits protein synthesis in cultured cells and inhibits the transport of secretory and lysosomal proteins at concentrations of 1-10 µg/mL. In HepG2 cells, BFA induces two blocks in the secretory pathway; one at the level of the endoplasmic reticulum-Golgi juncture and the other in the trans-Golgi network. Brefeldin A is used in the studies of Brefeldin A-inhibited Guanine Nucleotide-exchange Protein, BIG2, Regulates the Constitutive Release of TNFR1 Exosome-like Vesicles.
Supplier:
AMBEED, INC
Description:
1,2-Dimethoxy-4-Propenylbenzene, Purity: 98%, CAS Number: 93-16-3, Appearance: Form:Liquid Colour: Colorless - Slightly pale yellow, Storage: Sealed in dry, Room Temperature, Size: 5g
Catalog Number:
(76765-664)
Supplier:
AMBEED, INC
Description:
4-tert-Butylcyclohexylamine 95%
Catalog Number:
(95043-424)
Supplier:
G-Biosciences
Description:
G-Biosciences' Coomassie Brilliant Blue (CBB) G-250 and R-250 Stain are based on a colloidal Coomassie stain. CBB G-250 and R-250 stain proteins with high band visibility. The staining of gels with CBB G-250 and R-250 allows the examination of protein bands even during the staining process.
Catalog Number:
(77507-038)
Supplier:
VWR International
Description:
VWR®, part of Avantor has industry leading Anatomical Pathology reagents available for your lab.
Catalog Number:
(10234-980)
Supplier:
Bioss
Description:
Histones are highly conserved proteins that serve as the structural scaffold for the organization of nuclear DNA into chromatin. The four core histones, H2A, H2B, H3, and H4, assemble into an octamer (2 molecules of each). Subsequently, 146 base pairs of DNA are wrapped around the octamer, forming a nucleosome, the basic subunit of chromatin. Histone modifications regulate DNA transcription, repair, recombination, and replication. The most commonly studied modifications are acetylation, phosphorylation, methylation, and ubiquitination. These modifications can alter local chromatin architecture, or recruit trans-acting factors that recognize specific histone modifications (the "histone code" hypothesis). Trimethylation of histone H3 on Lys9 (H3K9me3) is one of the most highly studied epigenetic marks. H3K9me3 functions in the repression of euchromatic genes, and in epigenetic control of heterochromatin assembly, most likely via acting as a recognition motif for the binding of chromatin-associated proteins, such as Swi6 or HP1Alpha/Beta. The enzymes responsible for H3K9me3 formation are SUV39H1 and SUV39H2.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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