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Dai+Ki+Sciences+Co.+(USD)+Ltd
Catalog Number:
(10360-064)
Supplier:
Bioss
Description:
Synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system.
Catalog Number:
(76194-646)
Supplier:
Prosci
Description:
Recognizes a protein of ~140kDa, identified as N-Cadherin (NCAD), also known as CDH2 and CD325. CDH2 is a member of the Cadherin superfamily, and consists of five extracellular repeats, a transmembrane domain and a cytoplasmic domain. CDH2 deficient mice die at day 10 of gestation and embryos display major heart defects and malformed neural tubes and somites. Consistent with this, the protein has been implicated in several aspects of cardiac development including the precardiac mesoderm, establishment of left-right symmetry and cardiac looping morphogenesis. Furthermore, it is normally involved in inducing cell cycle arrest and its expression is frequently deregulated in cancer cells. Studies have linked N-cadherin to cancer metastasis by showing the aggressive tumor cells had preferentially turned on N-cadherin as opposed to E- or P-cadherin.
Catalog Number:
(76194-644)
Supplier:
Prosci
Description:
Recognizes a protein of ~140kDa, identified as N-Cadherin (NCAD), also known as CDH2 and CD325. NCAD is a member of the Cadherin superfamily, and consists of five extracellular repeats, a transmembrane domain and a cytoplasmic domain. NCAD/CD325 deficient mice die at day 10 of gestation and embryos display major heart defects and malformed neural tubes and somites. Consistent with this, the protein has been implicated in several aspects of cardiac development including the precardiac mesoderm, establishment of left-right symmetry and cardiac looping morphogenesis. Furthermore, it is normally involved in inducing cell cycle arrest and its expression is frequently deregulated in cancer cells. Studies have linked N-cadherin to cancer metastasis by showing the aggressive tumor cells had preferentially turned on N-cadherin as opposed to E- or P-cadherin.
Catalog Number:
(98000-386)
Supplier:
VWR International
Description:
26"W x 24"D x 3"H.
Catalog Number:
(10756-978)
Supplier:
Biolegend
Description:
Brilliant Violet 510™ anti-mouse TER-119/Erythroid Cells [TER-119]; Isotype: Rat IgG2b, κ; Reactivity: Mouse; Apps: FC; Size: 125 μl
Supplier:
MCR Safety
Description:
Whether working in the rugged oil and gas industry or spending the day working near electrical hazards, stay safe and comfortable in FR gear made with Max Comfortâ„¢ fabrics.
Catalog Number:
(10756-982)
Supplier:
Biolegend
Description:
Purified anti-mouse TER-119/Erythroid Cells (MaxPar® Ready) [TER-119]; Isotype: Rat IgG2b, κ; Reactivity: Mouse; Apps: FC, CyTOF®; Size: 100 μg
Catalog Number:
(103260-078)
Supplier:
Southern Biotechnology
Description:
CD21, also known as complement receptor 2, is expressed on all mature circulating B lymphocytes but not on T lymphocytes or natural killer cells. Low density CD21 has also been reported on granulocytes and monocytes. The monoclonal antibody BB6-11C9.6 stains the following percentages of surface immunoglobulin (sIg) positive cells in porcine lymphoid tissues - 92-96% in peripheral blood, 74-98% in mesenteric lymph nodes, 97-100% in ileal Peyer’s patches (ILPP), 93-97% in spleen, and 0% in thymus. The antibody does not stain B cells in cord blood or spleen from pig fetuses (105 days gestation).
Supplier:
Ansell Healthcare
Description:
KleenGuardâ„¢ 30-06 readers safety glasses are equipped to suit those who need vision assistance and eye protection. Available in a variety of lens and frame colors and prescription strengths, they are designed for long-term comfort.
Catalog Number:
(10299-616)
Supplier:
Bioss
Description:
GPCR2037 is a G protein-coupled receptor that undergoes weak activation by Galanin and is most abundant in the central nervous system (CNS), where it appears to be critical for development. During embryonal development the expression of GPCR2037 is widespread in the nervous system (dorsal thalamus, striatum, locus coeruleus and hindbrain nuclei). GPCR2037 in the CNS of 7- and 15-day-old mouse embryos can localize to the habenular complex. Low levels of GPCR2037 are detectable in testis, liver, kidney and stomach. In addition to GPCR2037, Galanin mediates its effects through receptor subtypes GALR1, 2 and 3. Galanin ligand exerts anxiolytic actions via GALR receptors under conditions of high stress. Galanin coexists with norepinephrine and serotonin in neural systems that mediate emotion.
Catalog Number:
(10299-464)
Supplier:
Bioss
Description:
GPCR2037 is a G protein-coupled receptor that undergoes weak activation by Galanin and is most abundant in the central nervous system (CNS), where it appears to be critical for development. During embryonal development the expression of GPCR2037 is widespread in the nervous system (dorsal thalamus, striatum, locus coeruleus and hindbrain nuclei). GPCR2037 in the CNS of 7- and 15-day-old mouse embryos can localize to the habenular complex. Low levels of GPCR2037 are detectable in testis, liver, kidney and stomach. In addition to GPCR2037, Galanin mediates its effects through receptor subtypes GALR1, 2 and 3. Galanin ligand exerts anxiolytic actions via GALR receptors under conditions of high stress. Galanin coexists with norepinephrine and serotonin in neural systems that mediate emotion.
Catalog Number:
(10103-516)
Supplier:
Prosci
Description:
Heparan sulfate proteoglycans (HSPGs) act as coreceptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. Heparan sulfate 6-O-endosulfatases, such as SULF2, selectively remove 6-O-sulfate groups from heparan sulfate. This activity modulates the effects of heparan sulfate by altering binding sites for signaling molecules.Heparan sulfate proteoglycans (HSPGs) act as coreceptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. Heparan sulfate 6-O-endosulfatases, such as SULF2, selectively remove 6-O-sulfate groups from heparan sulfate. This activity modulates the effects of heparan sulfate by altering binding sites for signaling molecules (Dai et al., 2005 [PubMed 16192265]).
Catalog Number:
(10317-066)
Supplier:
Bioss
Description:
C2orf61 (chromosome 2 open reading frame 61), also known as FLJ40172, is a 177 amino acid protein encoded by a gene that maps to human chromosome 2p21. As the second largest human chromosome, chromosome 2 makes up approximately 8% of the human genome and contains 237 million bases encoding over 1,400 genes. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstr syndrome, is related to mutations in the ALMS1 gene. Chromosome 2 contains a probable vestigial second centromere as well as vestigial telomeres, which gives credence to the hypothesis that human chromosome 2 formed as a result of an ancient fusion of two ancestral chromosomes, which are still present in modern day apes.
Catalog Number:
(100244-872)
Supplier:
Southern Biotechnology
Description:
CD21, also known as complement receptor 2, is expressed on all mature circulating B lymphocytes but not on T lymphocytes or natural killer cells. Low density CD21 has also been reported on granulocytes and monocytes. The monoclonal antibody BB6-11C9.6 stains the following percentages of surface immunoglobulin (sIg) positive cells in porcine lymphoid tissues - 92-96% in peripheral blood, 74-98% in mesenteric lymph nodes, 97-100% in ileal Peyer’s patches (ILPP), 93-97% in spleen, and 0% in thymus. The antibody does not stain B cells in cord blood or spleen from pig fetuses (105 days gestation).
Catalog Number:
(76107-332)
Supplier:
Bioss
Description:
Adipogenesis, the process of transforming pre-adipocytes into mature fat cells, is of particular interest due to the role adipocytes play in obesity and type II diabetes. Adipocytes have been shown to affect a variety of functions, including hemostasis, angiogenesis and energy balance, by secreting hormones and bioactive peptides. The FNDC3B protein, also designated FAD104 (factor for adipocyte differentiation 104) or HCV NS5A-binding protein 37, is expressed during early adipogenesis. Belonging to the FNDC3 family of proteins, FNDC3B is a 1,204 amino acid protein that contains nine fibronectin type-III domains. FNDC3B-deficient mice die within one day of birth, suggesting that FNDC3B is crucial for postpartum survival. Mouse embryonic fibroblasts (MEFs) with loss of FNDC3B function displayed a reduction in stress fiber formation, indicating a role for FNDC3B in cell proliferation, adhesion, spreading and migration.
Catalog Number:
(76120-204)
Supplier:
Bioss
Description:
C2orf29, also known as C40, is a 510 amino acid protein that belongs to the UPF0760 family and is encoded by a gene that maps to human chromosome 2q11.2. As the second largest human chromosome, chromosome 2 makes up approximately 8% of the human genome and contains 237 million bases encoding over 1400 genes. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstr syndrome, is related to mutations in the ALMS1 gene. Chromosome 2 contains a probable vestigial second centromere as well as vestigial telomeres, which gives credence to the hypothesis that human chromosome 2 formed as a result of an ancient fusion of two ancestral chromosomes, which are still present in modern day apes.
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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