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2,2\\\'-Dithiodi(benzoic+acid)
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2,2\\\'-Dithiodi(benzoic+acid)
Supplier:
Matrix Scientific
Description:
trans-Methyl 4-(hydroxymethyl)cyclohexanecarboxylate ≥97%
Supplier:
AMBEED, INC
Description:
α'-Bromo-α,α,α-trifluoro-o-xylene 98%
Catalog Number:
(89367-046)
Supplier:
Genetex
Description:
MAP kinases consist of several subgroups, including the ERK, JNK, and p38 kinases. The members are regulated by many different extracellular cues ranging from cytokines, growth factors, and neuropeptides. These stimuli activate cell surface receptors to stresses such as cold, heat, osmolarity changes and irradiation. The pathways regulated by the MAPKs control a broad array of cellular responses ranging from survival, cell proliferation, and apoptosis. The MAPKs family is also characterized by their requirement for dual phosphorylation at a conserved threonine and tyrosine residue for enzymatic activation and both must be phosphorylated for full enzymatic activation. The closely related ERK1 (44 kDa) and ERK2 (42 kDa) kinases are characterized by their requirement for dual phosphorylation at a conserved T-E-Y motif. While JNK1 is activated by dual phosphorylation at a T-P-Y motif and p38 is also activated by dual phosphorylation at a T-G-Y motif.
Catalog Number:
(102519-400)
Supplier:
Matrix Scientific
Description:
MF=C13H14F3N3O2 MW=301.27 MDL=MFCD20487140 250MG
Catalog Number:
(101845-484)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 038427-500MG , MDL Number: MFCD12027323
Catalog Number:
(75791-700)
Supplier:
Prosci
Description:
The EGFR subfamily of receptor tyrosine kinases is composed of EGFR, ErbB2, ErbB3 and ErbB4. The EGFR shares 43% - 44% aa sequence identity with the ECD of human EGFR subfamily. All these family members are type I transmembrane glycoproteins with an extracellular ligand binding domain. The extracellular ligand binding domain is containing two cysteine-rich domains separated by a spacer region and a cytoplasmic domain containing a membrane-proximal tyrosine kinase domain. Ligand binding could induce EGFR homodimerization and heterodimerization with ErbB2, resulting in cell signaling, heterodimerization tyrosine phosphorylation and kinase activation. It can bind EGF, amphiregulin, TGF-alpha, betacellulin, epiregulin, HB-EGF, epigen, and so on. Its signaling regulates multiple biological functions including cell proliferation, differentiation, motility, and apoptosis. EGFR can also be recruited to form heterodimers with the ligand-activated ErbB3 or ErbB4. EGFR is overexpressed in different tumors. Several anti-cancer drugs use EGFR as target.
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 057019-10G , MDL Number: MFCD00041152
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 046167-1G , MDL Number: MFCD09152718
Supplier:
ALADDIN SCIENTIFIC
Description:
(1S,2R)-(+)-2-Amino-1,2-diphenylethanol can be used:· To prepare vanadium(V) Schiff base complexes, which are used as catalysts in the oxidation of sulfides and olefins. · To prepare chiral selectors, which are immobilized on aminated silica gel, applicable as chiral stationary phase in HPLC. · To immobilize on the frame of α-zirconium phosphate to yield layered zirconium phosphonates, which are used in the heterogeneous catalysis. · As a chiral auxiliary in the preparation of homopropargylic alcohols from aliphatic and aromatic aldehydes.
Catalog Number:
(75875-730)
Supplier:
Tonbo Biosciences
Description:
The CD28.6 antibody reacts with human CD28, a 44 kDa type I surface glycoprotein which acts as a co-stimulatory receptor in support of the T cell receptor (TCR). CD28 exists as a homodimer with specificity for two known ligands, known as B7-1 (CD80) and B7-2 (CD86), which are expressed on activated B cells and antigen-presenting cells. These ligands trigger CD28 signaling in concert with TCR activation to drive T cell proliferation, induce high-level expression of IL-2, impart resistance to apoptosis, and enhance T cell cytotoxicity. The interaction / co-stimulatory signaling between the B7 ligands and CD28 provides crucial communication between T cells and B cells or APCs to coordinate the adaptive immune response. The CD28.6 antibody is reported to have neutralizing activity and is also useful for western blotting.
Catalog Number:
(101836-720)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 033969-500MG , MDL Number: MFCD03419610
Catalog Number:
(101842-352)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 036928-500MG , MDL Number: MFCD03144060
Catalog Number:
(101914-020)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 058115-1G , MDL Number: MFCD12974577
Catalog Number:
(101809-380)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 020091-500MG , MDL Number: MFCD07789060
Supplier:
Matrix Scientific
Description:
3-[1-(Difluoromethyl)-5-methyl-1H-pyrazol-3-yl]-6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepine
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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