Methyl+4-(1-aminocyclopropyl)benzoate+hydrochloride
Catalog Number:
(75843-150)
Supplier:
BIOGEMS INTERNATIONAL INC.
Description:
The A2F10 monoclonal antibody specifically reacts with mouse CD135, a tyrosine kinase class III receptor. CD135, also known as Flt3, Ly-72, and Flk-2, is the receptor for the FLT3 ligand (FLT3L) cytokine and is expressed on many hematopoietic progenitor cells. Signaling through CD135 plays a role in cell survival, proliferation, and differentiation. The A2F10 antibody is reported to inhibit the binding of FLT3L to CD135.
Catalog Number:
(10764-666)
Supplier:
Prosci
Description:
The 2.4G2 monoclonal antibody specifically reacts with an epitope on the extracellular domain of the mouse CD16 (Fc gamma III) and CD 32 (Fc gamma II). CD16 and CD32 are low affinity receptors for the IgG Fc domain and are expressed by B lymphocytes, NK cells, kupffer cells, mast cells, monocytes, macrophages, granulocytes, immature thymocytes, neutrophils, and some activated mature T cells.The 2.4G2 antibody blocks the binding of immunoglobulins to CD16 and CD32, and possibly to Fc gamma I receptor.
Catalog Number:
(10764-662)
Supplier:
Prosci
Description:
The 2.4G2 monoclonal antibody specifically reacts with an epitope on the extracellular domain of the mouse CD16 (Fc gamma III) and CD 32 (Fc gamma II). CD16 and CD32 are low affinity receptors for the IgG Fc domain and are expressed by B lymphocytes, NK cells, kupffer cells, mast cells, monocytes, macrophages, granulocytes, immature thymocytes, neutrophils, and some activated mature T cells.The 2.4G2 antibody blocks the binding of immunoglobulins to CD16 and CD32, and possibly to Fc gamma I receptor.
Catalog Number:
(PI37542)
Supplier:
Invitrogen
Description:
These StartingBlock™ blocking buffers are PBS and TBS formulations of a proprietary protein that provides exceptional performance and broad compatibility with membrane (Western blot) and 96-well plate (ELISA) assays.
Supplier:
BeanTown Chemical
Description:
CAS: 617-35-6; EC No: 210-511-2; MDL No: MFCD00009123
UN No: UN3272; Haz Class: 3; Packing Group: III
Liquid; Linear Formula: CH2COCOOCH2CH3; Molecular Formula: C5H8O3; MW: 116.12
Boiling Point: 144°; Flash point: 46°C (115°F)
Density (g/mL): 1.045; Refractive Index: 1.404
Catalog Number:
(75842-958)
Supplier:
BIOGEMS INTERNATIONAL INC.
Description:
The CB16 monoclonal antibody specifically reacts with human CD16, the low affinity IgG receptor III (FC gamma RIII). CD16 is expressed on granulocytes, monocytes, macrophages, and NK cells and plays a role in NK activation and signal transduction. CD16 is expressed as either CD16a or CD16b. CD16a is a polypeptide-anchored transmembrane protein and CD16b is a glycosylphosphatidylinositol (GPI)-anchored protein that is expressed exclusively on neutrophils.
Catalog Number:
(75842-960)
Supplier:
BIOGEMS INTERNATIONAL INC.
Description:
The CB16 monoclonal antibody specifically reacts with human CD16, the low affinity IgG receptor III (FC gamma RIII). CD16 is expressed on granulocytes, monocytes, macrophages, and NK cells and plays a role in NK activation and signal transduction. CD16 is expressed as either CD16a or CD16b. CD16a is a polypeptide-anchored transmembrane protein and CD16b is a glycosylphosphatidylinositol (GPI)-anchored protein that is expressed exclusively on neutrophils.
Supplier:
BeanTown Chemical
Description:
CAS: 7784-27-2; EC No: 236-751-8; MDL No: MFCD00003419; RTECS: BD1050000
UN No: UN1438; Haz Class: 5.1; Packing Group: III
Crystalline; Linear Formula: Al(NO3)3·9H2O ; MW: 375.13
Melting Point: 73°
Hygroscopic
Supplier:
BeanTown Chemical
Description:
CAS: 367-57-7; EC No: 206-698-5; MDL No: MFCD00000427
UN No: UN1224; Haz Class: 3; Packing Group: III
Liquid; Linear Formula: CF3COCH2COCH3; Molecular Formula: C5H5F3O2; MW: 154.09
Boiling Point: 105-107°; Flash point: 26°C (79°F)
Density (g/mL): 1.270; Refractive Index: 1.388
Catalog Number:
(10233-172)
Supplier:
Bioss
Description:
Receptor tyrosine kinase involved in the development and the maturation of the central and peripheral nervous systems through regulation of proliferation, differentiation and survival of sympathetic and nervous neurons. High affinity receptor for NGF which is its primary ligand, it can also bind and be activated by NTF3/neurotrophin-3. However, NTF3 only supports axonal extension through NTRK1 but has no effect on neuron survival. Upon dimeric NGF ligand-binding, undergoes homodimerization, autophosphorylation and activation. Recruits, phosphorylates and/or activates several downstream effectors including SHC1, FRS2, SH2B1, SH2B2 and PLCG1 that regulate distinct overlapping signaling cascades driving cell survival and differentiation. Through SHC1 and FRS2 activates a GRB2-Ras-MAPK cascade that regulates cell differentiation and survival. Through PLCG1 controls NF-Kappa-B activation and the transcription of genes involved in cell survival. Through SHC1 and SH2B1 controls a Ras-PI3 kinase-AKT1 signaling cascade that is also regulating survival. In absence of ligand and activation, may promote cell death, making the survival of neurons dependent on trophic factors. Isoform TrkA-III is resistant to NGF, constitutively activates AKT1 and NF-kappa-B and is unable to activate the Ras-MAPK signaling cascade. Antagonizes the anti-proliferative NGF-NTRK1 signaling that promotes neuronal precursors differentiation. Isoform TrkA-III promotes angiogenesis and has oncogenic activity when overexpressed.
Supplier:
DWK Life Sciences (KIMBLE)
Description:
Test tubes made from KG-33 borosilicate glass with a [ST] top and a [ST] glass stopper.
Supplier:
BeanTown Chemical
Description:
CAS: 68-12-2; EC No: 200-679-5; MDL No: MFCD00003284; RTECS: LQ2100000
UN No: UN2265; Haz Class: 3; Packing Group: III
Liquid; Linear Formula: HCON(CH3)2 ; Molecular Formula: C3H7NO; MW: 73.09
Melting Point: -61°; Boiling Point: 153°; Flash point: 57°C (135°F)
Density (g/mL): 0.944; Refractive Index: 1.430
Catalog Number:
(76236-828)
Supplier:
Rockland Immunochemical
Description:
Human VEGFR2 - KDR AccuSignal ELISA Kit
Supplier:
Tonbo Biosciences
Description:
The 2.4G2 antibody is specific for a common epitope found in the extracellular regions of mouse Fc-receptors Fc-gamma II (CD32) and Fc-gamma III (CD16). As these are receptors for the Fc portion of mouse IgG, they may also bind laboratory antibody preparations and products used in a variety of cell analysis protocols such as flow cytometry, immunohistochemistry and functional cell assays. The 2.4G2 antibody is therefore widely used as a pre-treatment reagent to block binding of specific antibodies of interest, e.g. fluorescently conjugated antibodies, to Fc receptors via their Fc domains and contributing to “non-specific” staining.
Catalog Number:
(76116-948)
Supplier:
Bioss
Description:
The autosomal dominant cerebellar ataxias (ADCA) are a heterogeneous group of neurodegenerative disorders characterized by progressive degeneration of the cerebellum, brain stem and spinal cord. Clinically, ADCA has been divided into three groups: ADCA types I-III. ATX2 belongs to the autosomal dominant cerebellar ataxias type I (ADCA I) which are characterized by cerebellar ataxia in combination with additional clinical features like optic atrophy, ophthalmoplegia, bulbar and extrapyramidal signs, peripheral neuropathy and dementia. ATX2 is caused by expansion of a CAG repeat in the coding region of ATX2. Longer expansions result in earlier onset of the disease. There are four named isoforms.
Catalog Number:
(10765-518)
Supplier:
Prosci
Description:
The 2.4G2 monoclonal antibody specifically reacts with an epitope on the extracellular domain of the mouse CD16 (Fc gamma III) and CD 32 (Fc gamma II). CD16 and CD32 are low affinity receptors for the IgG Fc domain and are expressed by B lymphocytes, NK cells, kupffer cells, mast cells, monocytes, macrophages, granulocytes, immature thymocytes, neutrophils, and some activated mature T cells.The 2.4G2 antibody blocks the binding of immunoglobulins to CD16 and CD32, and possibly to Fc gamma I receptor.
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