H-d-Ser(tBu)-OMe·HCl
Catalog Number:
(TS46182-0050)
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
Metoclopramide hydrochloride ≥98%
Supplier:
AMBEED, INC
Description:
5,6,7,8-Tetrahydro-1,6-naphthyridine hydrochloride 95%
Supplier:
TLC PHARMACEUTICAL STANDARD LTD
Description:
Pharmaceutical Standards, Minodronic Acid Impurity 31-d3 HCl (Acetyl-d3)
Supplier:
AMBEED, INC
Description:
Glycine-tert-butyl ester hydrochloride(H-Gly-OtBu.HCl) 98%
Supplier:
Ricca Chemical
Description:
1000 ppm Li ion in dilute HCl. For use in standardizing atomic absorption spectrophotometers. 100mL.
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Supplier:
BeanTown Chemical
Description:
CAS: 328-38-1; EC No: 206-327-7; MDL No: MFCD00063088; RTECS: OH2840000
Crystalline; Molecular Formula: C6H13NO2; MW: 131.17
Optical Rotation: [α]23/D -14.7°, c = 2 in 5M HCl
Supplier:
AMBEED, INC
Description:
3-Deazaneplanocin A hydrochloride ≥98%, Ambeed.Inc
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 012670-100G , MDL Number: MFCD01863289
Catalog Number:
(10338-778)
Supplier:
Bioss
Description:
p21-activated kinases (PAKs) belong to the family of serine/threonine kinases involved in the control of various cellular processes, including the cell cycle, dynamics of the cytoskeleton, apoptosis, oncogenic transformation, and transcription. All PAK family members are characterized by the presence of p21-binding domain. p21-activated kinases are regulated by the small GTP-binding proteins Rac and Cdc42, and lipids, which stimulate autophosphorylation and phosphorylation of exogenous substrates. Serine (Ser-474) is the likely autophosphorylation site in the kinase domain of PAK4 in vivo. Phosphospecific directed against serine 474 detect activated PAK4 on the Golgi membrane when PAK4 is co-expressed with activated Cdc42. Current data strongly implicates PAK-4 in oncogenesis. PAK4 is frequently overexpressed in human tumor cell lines of various tissue origins. Serine/threonine protein kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell migration, proliferation or cell survival. Activation by various effectors including growth factor receptors or active CDC42 and RAC1 results in a conformational change and a subsequent autophosphorylation on several serine and/or threonine residues. Phosphorylates the proto-oncogene RAF1 and stimulates its kinase activity. Promotes cell survival by phosphorylating the BCL2 antagonist of cell death BAD. Phosphorylates CTNND1, probably to regulate cytoskeletal organization and cell morphology. Keeps microtubules stable through MARK2 inhibition and destabilizes the F-actin network leading to the disappearance of stress fibers and focal adhesions.
Catalog Number:
(89146-214)
Supplier:
Enzo Life Sciences
Description:
VASP (vasodilator stimulated phosphoprotein) is a proline-rich protein substrate of cAMP- and cGMP-dependent protein kinases. Phosphorylation of VASP at Ser-157 causes a mobility shift in SDS gel electrophoresis from 46 to 50 kDa, which has been used as a convenient marker to monitor cyclic nucleotide-dependent protein kinase activity. VASP is the founding member of the Ena-VASP protein family, comprising the Drosophila protein Enabled (Ena), its mouse homologue Mena (mammalian Enabled), and mouse EVL (Ena-VASP-like protein). With these proteins VASP shares a conserved overall domain organization:
a) the conserved N-terminal Ena-VASP homology domain 1 (EVH1), which mediates binding to a proline-rich motif b) a more divergent proline-rich central domain (which is responsible for profilin binding) c) a conserved C-terminal EVH2 domain. VASP is expressed in a variety of mammalian cell types and tissues. In cultured cells, VASP is associated with focal adhesions, cell-cell contacts, microfilaments, and highly dynamic membrane regions. From in vitro binding data VASP has been suggested to link profilin to zyxin, vinculin, and the Listeria spp. surface protein ActA, respectively. Functional evidence indicates that VASP is a crucial factor involved in the enhancement of actin filament formation and the actin-dependent motility of intracellular bacterial pathogens.
Supplier:
AMBEED, INC
Description:
(R)-N-(3-Aminopropyl)-N-(1-(3-benzyl-7-chloro-4-oxo-4H-chromen-2-yl)-2-methylpropyl)-4-methylbenzamide hydrochloride ≥98%
Supplier:
Thermo Scientific Chemicals
Description:
MDL: MFCD00012802
Beilstein Registry No.: 3615340
Fieser: 1,964 2,352 3,239 4,415
Catalog Number:
(76204-604)
Supplier:
HCL Label
Description:
This easy to use adhesive label is a great value.
Supplier:
MilliporeSigma
Description:
N, N-Diethylethanolammonium chloride for synthesis, Cas Number: 13989-32-7, Synonyms: N, N-Diethyl-2-hydroxyethylammonium chloride, 2-Diethylaminoethanol hydrochloride, Chemical formula: (C2H5)2NCH2CH2OH * HCl, 1kg.
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