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FLUO+3\\\/AM
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FLUO+3\\\/AM
Supplier:
Bachem Americas
Description:
See also H-8150 and N-1405.
Catalog Number:
(10454-216)
Supplier:
Bioss
Description:
Membrane glycoproteins implicated in the pathologic deposition of cholesterol in arterial walls during atherogenesis. Two types of receptor subunits exist. These receptors mediate the endocytosis of a diverse group of macromolecules, including modified low density lipoproteins (LDL). Isoform III does not internalize acetylated LDL.
Catalog Number:
(RL012-0603)
Supplier:
Rockland Immunochemical
Description:
1mg. Antibody Concentration: 1 mg/mL. Biotin/Protein Ratio: 10-20 BAC molecules per rat IgG molecule. Buffer: 0.02M potassium phosphate, 0.15M sodium chloride, pH 7.2. Stabilizer: 10 mg/ml Bovine Serum Albumin IgG and protease free. Lyophilized.
Catalog Number:
(10793-496)
Supplier:
Genetex
Description:
Rabbit Polyclonal antibody to VEGFR-2 (kinase insert domain receptor (a type III receptor tyrosine kinase))
Catalog Number:
(10386-646)
Supplier:
Bioss
Description:
G-protein coupled receptor that functions as receptor for endogenous enkephalins and for a subset of other opioids. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Plays a role in the perception of pain and in opiate-mediated analgesia. Plays a role in developing analgesic tolerance to morphine.
Catalog Number:
(10448-482)
Supplier:
Bioss
Description:
Inositol 1,4,5-triphosphate (IP3) functions as a second messenger for a myriad of extracellular stimuli including hormones, growth factors and neurotransmitters. Receptor tyrosine kinases indirectly increase the intracellular levels of IP3 through the activation of phospholipases such as phospholipase C (PLC), which convert phosphatidylinositol-4,5 bisphosphate into IP3 and diacylglycerol (DAG). The inositol 1,4,5-triphosphate receptor, IP3R, acts as an inositol triphosphate (IP3)-gated calcium release channel in a variety of cell types. Three IP3 receptor subtypes have been described and are designated IP3R-I, IP3R-II and IP3R-III. IP3R-I is the predominant IP3R subtype expressed in neuronal tissues and the central nervous system, but is also expressed at high levels in the liver.
Catalog Number:
(10448-484)
Supplier:
Bioss
Description:
Inositol 1,4,5-triphosphate (IP3) functions as a second messenger for a myriad of extracellular stimuli including hormones, growth factors and neurotransmitters. Receptor tyrosine kinases indirectly increase the intracellular levels of IP3 through the activation of phospholipases such as phospholipase C (PLC), which convert phosphatidylinositol-4,5 bisphosphate into IP3 and diacylglycerol (DAG). The inositol 1,4,5-triphosphate receptor, IP3R, acts as an inositol triphosphate (IP3)-gated calcium release channel in a variety of cell types. Three IP3 receptor subtypes have been described and are designated IP3R-I, IP3R-II and IP3R-III. IP3R-I is the predominant IP3R subtype expressed in neuronal tissues and the central nervous system, but is also expressed at high levels in the liver.
Catalog Number:
(102995-710)
Supplier:
Cell Sciences
Description:
Flow Cytometry: Use 10 µl to label 1x10E6 cells or 100 µl of whole blood.
Supplier:
BeanTown Chemical
Description:
CAS: 1344-28-1; MDL No: MFCD00003424
UN No: UN1950; Haz Class: 2.1
Aerosol Spray Can; Molecular Formula: Al2O3; MW: 101.96
Supplier:
BeanTown Chemical
Description:
CAS: 1336-21-6; EC No: 215-647-6; MDL No: MFCD00066650
UN No: UN2672; Haz Class: 8; Packing Group: III
Liquid; Linear Formula: NH4OH; MW: 35.05
Density (g/mL): 0.9
Catalog Number:
(76083-958)
Supplier:
Bioss
Description:
This gene encodes a serine/threonine protein kinase that plays an important role in cellular stress response. This kinase activates certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. High levels of expression of this gene may contribute to conditions such as hypertension and diabetic nephropathy. Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Catalog Number:
(10288-546)
Supplier:
Bioss
Description:
Component of a heterodimeric G-protein coupled receptor for GABA, formed by GABBR1 and GABBR2. Within the heterodimeric GABA receptor, only GABBR1 seems to bind agonists, while GABBR2 mediates coupling to G proteins. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase, stimulates phospholipase A2, activates potassium channels, inactivates voltage-dependent calcium-channels and modulates inositol phospholipid hydrolysis. Plays a critical role in the fine-tuning of inhibitory synaptic transmission. Pre-synaptic GABA receptor inhibits neurotransmitter release by down-regulating high-voltage activated calcium channels, whereas postsynaptic GABA receptor decreases neuronal excitability by activating a prominent inwardly rectifying potassium (Kir) conductance that underlies the late inhibitory postsynaptic potentials. Not only implicated in synaptic inhibition but also in hippocampal long-term potentiation, slow wave sleep, muscle relaxation and antinociception.
Catalog Number:
(10485-120)
Supplier:
Bioss
Description:
FNDC1, also known as MEL4B3, Ags8, Expressed in synovial lining protein and Activation-associated cDNA protein, is a 1888 amino acid secreted protein that contains five fibronectin type-III domains. FNDC1 is moderately expressed in skeletal muscle, pancreas, heart, kidney, spinal cord, ovary and lung. Expression of FNDC1 is induced in response to hypoxia in ventricular cardiomyocytes. Since FNDC1 interacts with G∫ and G©, it is likely that FNDC1 is an activator for G-protein signaling. Though normally absent in healthy skin, FNDC1 expression is induced by TGF-beta signaling in skin tumors and psoriasis. There are two isoforms of FNDC1 that are produced as a result of alternative splicing events.
Supplier:
BeanTown Chemical
Description:
CAS: 6018-94-6; EC No: 208-933-7; MDL No: MFCD00167155
UN No: UN3077; Haz Class: 9; Packing Group: III
Powder; Linear Formula: NiC2O4·2H2O; MW: 182.74
Supplier:
BeanTown Chemical
Description:
CAS: 7440-74-6; EC No: 231-180-0; MDL No: MFCD00134048; RTECS: NL1050000
UN No: UN3089; Haz Class: 4.1; Packing Group: III
Powder; Molecular Formula: In; MW: 114.82
Melting Point: 156.6°; Boiling Point: 2072°
Density (g/mL): 7.3
Supplier:
Adipogen
Description:
Antidiabetic compound. Binds to and activates the ATP-sensitive potassium channels (KATP) inhibitory regulatory subunit sulfonylurea receptor 1 (SUR1). Causes cell membrane depolarization and opening of voltage-dependent calcium channel. Increases intracellular calcium and stimulates insulin secretion in beta cells NLRP3 inflammasome inhibitor. Broad-spectrum ATP-binding cassette (ABC) transporter inhibitor. Shown to have anti-leishmanial activity. Potential inhibitor of collagenases.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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