You Searched For: R+

Catalog Number: (10347-198)

Supplier: Bioss

Description: Key regulator of entry into cell division that acts as a tumor suppressor. Promotes G-G1 transition when phosphorylated by CDK3/cyclin-C. Acts as a transcription repressor of E2F1 target genes. The underphosphorylated, active form of RB1 interacts with E2F1 and represses its transcription activity, leading to cell cycle arrest. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransferases SUV39H1, SUV42H1 and SUV42H2, leading to epigenetic transcriptional repression. Controls histone H4 'Lys-2' trimethylation. Inhibits the intrinsic kinase activity of TAF1. Mediates transcriptional repression by SMARCA4/BRG1 by recruiting a histone deacetylase (HDAC) complex to the c-FOS promoter. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex (By similarity). In case of viral infections, interactions with SV4 large T antigen, HPV E7 protein or adenovirus E1A protein induce the disassembly of RB1-E2F1 complex thereby disrupting RB1's activity.

Catalog Number: (89289-116)

Supplier: Genetex

Description: Rabbit Polyclonal antibody to Claudin 13

Catalog Number: (10331-658)

Supplier: Bioss

Description: MRas is a member of the RAS superfamily of GTP-binding proteins which are membrane-anchored, intracellular signal transducers responsible for a variety of normal cellular functions. They are oncogenically activated in a significant fraction of tumors. MRas participates in reorganisation of actin cytoskeleton. It is also involved in focal adhesion and can activate MAPK signalling.

Catalog Number: (89302-790)

Supplier: Genetex

Description: Rabbit polyclonal to TRAP (N-term)

Catalog Number: (89300-422)

Supplier: Genetex

Description: Rabbit Polyclonal antibody to OVCA1

Catalog Number: (89270-700)

Supplier: Genetex

Description: Rabbit Polyclonal antibody to Cav beta 2

Catalog Number: (89268-638)

Supplier: Genetex

Description: Rabbit polyclonal antibody to TIGD3 (Middle)

Catalog Number: (89270-998)

Supplier: Genetex

Description: Rabbit polyclonal antibody to SLC1A2 (N-terminal)

Catalog Number: (89300-538)

Supplier: Genetex

Description: Rabbit polyclonal to ACCN2 (C-term)

Catalog Number: (89291-072)

Supplier: Genetex

Description: Rabbit Polyclonal antibody to NKX26 Purity: Immunoge affinity-chromatography. Species Reactivity: Human Tested Applications: ELISA WB Pkg Size: 100 ug

Catalog Number: (RL100-401-192)

Supplier: Rockland Immunochemical

Description: Primary Rabbit Anti-CIITA Reacts with Human, Mouse, Rat

Catalog Number: (89266-468)

Supplier: Genetex

Description: Rabbit polyclonal antibody to FAM83E (Middle)

Catalog Number: (89278-050)

Supplier: Genetex

Description: Rabbit Polyclonal to Human CELSR2

Catalog Number: (89268-656)

Supplier: Genetex

Description: Rabbit polyclonal antibody to AGXT2 (N-terminal)

Catalog Number: (89301-354)

Supplier: Genetex

Description: Rabbit polyclonal to KLRC2 (N-term)

Catalog Number: (89268-460)

Supplier: Genetex

Description: Rabbit polyclonal antibody to SEMA6D (N-terminal)