trans-3,5-dimethylmorpholine+hydrochloride
Supplier:
AMBEED, INC
Description:
Methyl 4-amino-3-(tert-butyl)benzoate hydrochloride, Purity: 97%, CAS Number: 2044702-89-6, Appearance: Solid, Storage: Inert atmosphere, 2-8 C, Size: 100mg
Catalog Number:
(101941-910)
Supplier:
Matrix Scientific
Description:
2-Chloromethylimidazo[1,2-A]Pyridine Hydrochloride, MF=C8H8Cl2N2 MW=203.07 CAS: 112230-20-3 5G
Catalog Number:
(101934-180)
Supplier:
Matrix Scientific
Description:
3-Amino-Indan-5-Sulfonic Acid Amide Hydrochloride, MF=C9H13Cln2O2S MW=248.73 250Mg
Catalog Number:
(101934-364)
Supplier:
Matrix Scientific
Description:
4-Methyl-2-Piperidin-4-Yl-6-Trifluoromethyl-Pyrimidine Hydrochloride, MF=C11H15Clf3N3 MW=281.71 250Mg
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
(1H-Imidazol-4-yl)methanol hydrochloride 99%
Supplier:
TCI America
Description:
CAS Number: 18807-73-3
MDL Number: MFCD00270149 Molecular Formula: C12H18N2O2 Molecular Weight: 258.75 Purity/Analysis Method: >97.0% (T) Form: Crystal
Catalog Number:
(10400-024)
Supplier:
Bioss
Description:
Hydrolase that deubiquitinates target proteins such as FOXO4, p53/TP53, MDM2, ERCC6, DNMT1, UHRF1, PTEN and DAXX. Together with DAXX, prevents MDM2 self-ubiquitination and enhances the E3 ligase activity of MDM2 towards p53/TP53, thereby promoting p53/TP53 ubiquitination and proteasomal degradation. Deubiquitinates p53/TP53 and MDM2 and strongly stabilizes p53/TP53 even in the presence of excess MDM2, and also induces p53/TP53-dependent cell growth repression and apoptosis. Deubiquitination of FOXO4 in presence of hydrogen peroxide is not dependent on p53/TP53 and inhibits FOXO4-induced transcriptional activity. In association with DAXX, is involved in the deubiquitination and translocation of PTEN from the nucleus to the cytoplasm, both processes that are counteracted by PML. Involved in cell proliferation during early embryonic development. Involved in transcription-coupled nucleotide excision repair (TC-NER) in response to UV damage: recruited to DNA damage sites following interaction with KIAA1530/UVSSA and promotes deubiquitination of ERCC6, preventing UV-induced degradation of ERCC6. Contributes to the overall stabilization and trans-activation capability of the herpesvirus 1 trans-acting transcriptional protein ICP0/VMW110 during HSV-1 infection. Involved in maintenance of DNA methylation via its interaction with UHRF1 and DNMT1: acts by mediating deubiquitination of UHRF1 and DNMT1, preventing their degradation and promoting DNA methylation by DNMT1. Exhibits a preference towards 'Lys-48'-linked ubiquitin chains. Increases regulatory T-cells (Treg) suppressive capacity by deubiquitinating and stabilizing the transcription factor FOXP3 which is crucial for Treg cell function (PubMed:23973222).
Supplier:
AMBEED, INC
Description:
5-Fluoro-2-methylphenylhydrazine hydrochloride 95%
Supplier:
AMBEED, INC
Description:
4-Methoxy-N-methylbenzylamine hydrochloride 95%
Supplier:
AOB CHEM USA
Description:
3,5-Dichloro-2-methylphenylboronic acid ≥97%
Catalog Number:
(76774-702)
Supplier:
AMBEED, INC
Description:
(R)-(-)-1-Benzyl-3-hydroxypiperidine hydrochloride 95%
Supplier:
Matrix Scientific
Description:
2-Bromo-3,5-dichloropyridine 98 for synthesis
Catalog Number:
(10351-994)
Supplier:
Bioss
Description:
Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity (By similarity). Interacts with MCMBP.
Catalog Number:
(101836-898)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 034058-500MG , MDL Number: MFCD11506565
Supplier:
TCI America
Description:
CAS Number: 112-79-8
MDL Number: MFCD00063954 Molecular Formula: C18H34O2 Molecular Weight: 282.47 Purity/Analysis Method: >97.0% (T) Form: Crystal Boiling point (°C): 288 Melting point (°C): 44 Flash Point (°C): 88 Storage Temperature: 0-10°C
Supplier:
AOB CHEM USA
Description:
3,5-Dibromo-2-isopropoxybenzoic acid ≥97%
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