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Anti-CD95 Mouse Monoclonal Antibody (RPE (R-Phycoerythrin)) [clone: DX2]

Supplier: Southern Biotechnology

9730-09 9730-09S

100246-394EA 371.38 USD

100246-394 103260-222

Anti-CD95 Mouse Monoclonal Antibody (RPE (R-Phycoerythrin)) [clone: DX2]

Antibodies

CD95, also known as Fas and APO-1, is a 45 kDa type I transmembrane glycoprotein and a member of the tumor necrosis factor receptor superfamily. It is expressed by activated lymphocytes, monocytes, neutrophils, fibroblasts, and cell lines. Fas ligand binding to CD95 induces apoptosis in activated mature lymphocytes thereby playing a role in maintaining peripheral tolerance. Crosslinking of CD95 by the monoclonal antibodies DX2 and DX3 delivers an apoptotic signal to Fas-sensitive cells indicating that these monoclonal antibodies recognize a functional epitope of CD95.

Type: Primary
Antigen: CD95
Clonality: Monoclonal
Clone: DX2
Conjugation: RPE (R-Phycoerythrin)
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity: Human, Rhesus, African Green Monkey, Sooty Mangabey

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