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Cyclopropyl(2,3-dichloropyridin-4-yl)methanone
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Cyclopropyl(2,3-dichloropyridin-4-yl)methanone
Supplier:
Adipogen
Description:
Major metabolite of pentoxifylline. Most effective metabolite at reducing oxygen radical production by polymorphonuclear leukocytes (PMN).
Supplier:
TCI America
Description:
6-Bromocoumarin-3-carboxylic Acid, Purity: >98.0%(HPLC), Cas no. 2199-87-3, Molecular formula: C10H5BrO4, Form: Crystal- Powder, Colour: White - Pale yellow, Size: 5G
Catalog Number:
(10751-192)
Supplier:
Prosci
Description:
ZBTB3 Antibody: The ZBTB family of proteins is comprised of diverse zinc finger proteins that also contain a BTB (BR-C, ttk and bab) domain. While little is known about ZBTB3, the related protein ZBTB2 is thought to be phosphorylated in response to the DNA damage, probably by either ATM or ATR. Other ZBTB proteins, such as ZBTB4 and ZBTB38 bind methylated DNA and repress transcription, suggesting that ZBTB3 may also act as a transcription repressor.
Catalog Number:
(101928-952)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 065076-500MG , MDL Number: MFCD05027533
Supplier:
Matrix Scientific
Description:
2-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-3-phenylpropanoic acid
Catalog Number:
(101928-522)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 064861-500MG , MDL Number: MFCD09851287
Catalog Number:
(101928-530)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 064865-500MG , MDL Number: MFCD00705985
Catalog Number:
(76012-540)
Supplier:
Prosci
Description:
This gene was identified as a retinoid acid (RA) receptor-responsive gene. It encodes a type 1 membrane protein. The expression of this gene is upregulated by tazarotene as well as by retinoic acid receptors. The expression of this gene is found to be downregulated in prostate cancer, which is caused by the methylation of its promoter and CpG island. Alternatively spliced transcript variant encoding distinct isoforms have been observed.
Supplier:
AMBEED, INC
Description:
3-(3-(2H-Benzo[d][1,2,3]triazol-2-yl)-5-(tert-butyl)-4-hydroxyphenyl)propanoic acid, Purity: 97%, CAS Number: 84268-36-0, Appearance: Solid, Storage: Sealed in dry, 2-8 C, Size: 5g
Catalog Number:
(76009-558)
Supplier:
Prosci
Description:
mDnmt3L (DNA methyltransferase 3L) does not appear to be catalytically active due to loss of the critical active site residues. It may function not directly as a DNA methyltransferase but rather as a regulator of methylation at imprinted loci. It is required specifically for the establishment of genomic imprints but is dispensable for their propagation. It is essential for the de novo methylation of single-copy DNA sequences. The protein is well-express in testis, thymus, ovary, and heart. mDnmt3L, which belongs to the 5-cytosine methyltransferase family, contains 1 ADD-type zinc finger.
Catalog Number:
(10310-538)
Supplier:
Bioss
Description:
C1orf77, also known as Friend of PRMT1 protein, is a 248 amino acid protein that plays an essential role in the ligand-dependent activation of estrogen receptor target genes. C1orf77 is tightly associated with chromatin and is modified by both asymmetric and symmetric arginine methylation. Depletion of C1orf77 results in almost complete block of estradiol-induced promter occupancy by the estrogen receptor. Also, complete knockdown of C1orf77 mRNA in adult erythroid progenitors stongly induces fetal hemoglobin, suggesting that C1orf77 is a critical modulator of _-globin gene expression. There are two isoforms of C1orf77 that are produced as a result of alternative splicing events. The gene encoding C1orf77 maps to human chromosome 1, the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1.
Catalog Number:
(101928-904)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 065052-500MG , MDL Number: MFCD00708042
Catalog Number:
(10481-132)
Supplier:
Bioss
Description:
The Dumpy-30 (DPY-30) protein was first described in C. elegans, in which it is involved in dosage compensation of sex chromosomes. Conserved from yeast to humans, the DPY-30 family is involved in gene expression and chromatin modification, specifically histone methylation. DPY-30 and closely related proteins contain a short motif that is related to the dimerization motif in the regulatory subunit of protein kinase A (PKA), which consists of two ?helices that form a four-helix bundle during dimerization. As a member of the DPY-30 family, DYDC1 (DPY30 domain-containing protein 1), also known as DPY30D1 and RSD9, is a 177 amino acid protein that binds to Endophilin III and plays a crucial role during acrosome biogenesis. DYDC1 is specifically expressed in brain and testis and accumulates in the acrosome area during spermatogenesis. Knockdown of DYDC1 mRNA results in disruption of acrosome formation and spermatid differentiation.
Supplier:
AMBEED, INC
Description:
(E)-4-(2-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)prop-1-en-1-yl)benzoic acid, Purity: 98%, CAS Number: 71441-28-6, Appearance: Form: solid, Storage: Sealed in dry, Store in freezer, under -20 C, Size: 5mg
Supplier:
AMBEED, INC
Description:
1H,2H,3H,4H,5H-Pyrido[4,3-b]indole-8-carboxylic acid hydrochloride, Purity: 95%, CAS Number: 1156899-12-5, Appearance: Solid, Storage: Inert atmosphere, Room Temperature, Size: 1G
Catalog Number:
(10481-124)
Supplier:
Bioss
Description:
The Dumpy-30 (DPY-30) protein was first described in C. elegans, in which it is involved in dosage compensation of sex chromosomes. Conserved from yeast to humans, the DPY-30 family is involved in gene expression and chromatin modification, specifically histone methylation. DPY-30 and closely related proteins contain a short motif that is related to the dimerization motif in the regulatory subunit of protein kinase A (PKA), which consists of two ?helices that form a four-helix bundle during dimerization. As a member of the DPY-30 family, DYDC1 (DPY30 domain-containing protein 1), also known as DPY30D1 and RSD9, is a 177 amino acid protein that binds to Endophilin III and plays a crucial role during acrosome biogenesis. DYDC1 is specifically expressed in brain and testis and accumulates in the acrosome area during spermatogenesis. Knockdown of DYDC1 mRNA results in disruption of acrosome formation and spermatid differentiation.
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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