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1-(2,3-Difluoro-4-iodophenyl)ethanol
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1-(2,3-Difluoro-4-iodophenyl)ethanol
Supplier:
Adipogen
Description:
Neratinib (HKI-272) is an orally available, irreversible tyrosine kinase inhibitor with IC(50) values of 59nM and 92nM for HER2 and EGFR, respectively. It is in development for the treatment of early- and late-stage HER2-positive breast cancer.
Supplier:
Adipogen
Description:
PF04217903 is a novel orally bio-available, small molecule tyrosine kinase inhibitor with potential anti-neoplastic activity. It is an extremely selective MET inhibitor, with an IC(50) of 4.8nM.
Supplier:
MilliporeSigma
Description:
Inhibitor of calpain I (Ki=190nM), calpain II (Ki=220nM), cathepsin B (Ki=150nM) and cathepsin L (Ki=0.5nM). Inhibits neutral cysteine proteases and the proteasome (Ki=6µM). Protects against neuronal damage caused by hypoxia and ischemia. Inhibits apoptosis in thymocytes and metamyelocytes. Also inhibits retrovirus-induced apoptosis in L929 cells. Inhibits the proteolysis of I[kappa]B-[alpha] and I[kappa]B-[beta] by the ubiquitin-proteasome complex. Inhibits cell cycle progression at G1/S and metaphase/anaphase in CHO cells by inhibiting cyclin B degradation. Also prevents nitric oxide production by activated macrophages by interfering with transcription of the inducible nitric oxide synthase gene.
Catalog Number:
(80058-662)
Supplier:
MilliporeSigma
Description:
Polyamine that plays an important role in the regulation of cellular proliferation and differentiation. Inhibits neuronal nitric oxide synthase.
Supplier:
G-Biosciences
Description:
Glutathione Resin is designed for the affinity purification of proteins with a glutathione S-transferase (GST) tag. The resin consists of reduced glutathione (GSH) covalently coupled to 6% cross-linked agarose, via a 10-carbon spacer arm. The resin has a binding capacity of >40mg GST/ml resin.
Supplier:
BeanTown Chemical
Description:
CAS: 75-80-9; EC No: 200-903-1; MDL No: MFCD00004671; RTECS: KM3675000
Solid; Linear Formula: Br3CCH2OH; Molecular Formula: C2H3Br3O; MW: 282.76
Melting Point: 73-79°; Boiling Point: 92-93°/10 mmHg
Light Sensitive
Supplier:
Rigaku Reagents
Description:
Use our stock solutions directly or as a component in solutions you create in your own lab. We prepare our stock solutions using high quality raw materials, ASTM Type 1 water, and sterile packaging. Our stock solutions are intended for Research and Development Use Only.
Supplier:
TCI America
Description:
CAS Number: 23364-44-5
MDL Number: MFCD00074959 Molecular Formula: C14H15NO Molecular Weight: 213.28 Purity/Analysis Method: >99.0% (GC,T) Form: Crystal Melting point (°C): 144 Specific rotation [a]20/D: 7 deg (C=0.6, EtOH)
Catalog Number:
(IC15058980)
Supplier:
MP Biomedicals
Description:
Cesium chloride is used for the preparation of electrically conducting glasses. It is also used to make solutions for the separation of RNA from DNA by density gradient centrifugation.
Catalog Number:
(76520-078)
Supplier:
VWR International
Description:
Includes an extra wire frame shelf made to fit VWR® Standard Series Chromatography units.
Catalog Number:
(76457-480)
Supplier:
VWR International
Description:
VWR® Stainless Steel Surgical Scalpel Blades are made from sharp, long lasting surgical stainless steel.
Supplier:
Adipogen
Description:
Precursor of cholesterol and vitamin D3. It is reduced to cholesterol by the enzyme 3beta-hydroxysterol-Delta7-reductase (DHCR7) in the last step of cholesterol biosynthesis. Mutations in the gene encoding DHCR7 lead to increased levels of 7-DHC and the neurodevelopmental syndrome Smith-Lemli-Opitz syndrome (SLOS). 7-DHC is used as a biomarker for SLOS screenings. Inhibits human fibroblast sphingomyelinase. Shown to have cytotoxic effects on melanoma cells. In skin, photolysis of 7-DHC by ultraviolet light produces vitamin D3. UV/Vis: lambdamax 271, 282, 293nm.
Catalog Number:
(IC15376525)
Catalog Number:
(80058-450)
Supplier:
MilliporeSigma
Description:
An antioxidant and a selective lipoxygenase (LOX) inhibitor (IC50=200nM, 30µM and 30µM for 5-LOX, 12-LOX and 15-LOX, respectively) over cyclooxygenase (IC50=100µM)
Catalog Number:
(101411-010)
Supplier:
Electron Microscopy Sciences
Description:
Alcoholic stain solutions are available with Congo Red 0.2%, Hematoxylin 1% in 95% alcohol, Iodine 0.5% in 95% alcohol, Iodine 0.5% in 85% alcohol, Iodine 2% in 85% alcohol, Saffron 6%, Thionin 0.5% in 20% alcohol, Aldehyde Fuchsin and Alum Hematoxylin.
Supplier:
MP Biomedicals
Description:
Folic acid, also known as folate, is a B vitamin that can be found in a variety of fruits and vegetables. It can also be chemically synthesized. Folate, a watersoluble vitamin, helps the body form red blood cells and aids in the formation of genetic material within every body cell. This product exhibits metal binding properties. Hematopoietic vitamin present, free or combined with one or more additional molecules of L-(+)-glutamic acid, in liver, kidney, mushrooms, spinach, yeast, green leaves, and grasses.
Folic acid (Vitamin B9 and folate) is essential to numerous bodily functions. The human body needs folate to synthesize DNA, repair DNA, and methylate DNA as well as to act as a cofactor in certain biological reactions. It is especially important in aiding rapid cell division and growth, such as in infancy and pregnancy. Folic acid (FA) and dihydrofolic acid (FAH2) are substrates of dihydrofolate reductase(s) which reduce them to tetrahydrofolate (THF), which in turn supports ‘one carbon’ transfer. Tetrahydrofolates are required for de novo synthesis of purines, thymidylic acid and various amino acids and for post-translational methylation (epigenetics). Very slightly soluble in cold water (0.0016 mg/mL at 25 °C), soluble to about 1% in boiling water. Slightly soluble in methanol, appreciably less soluble in ethanol and butanol. Insoluble in acetone, chloroform, ether, benzene. Relatively soluble in acetic acid, phenol, pyridine, solutions of alkali hydroxides and carbonates. Soluble in hot dilute HCl and H2SO4.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
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The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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