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Update to Avantor’s response to the coronavirus (COVID-19) pandemic

7-Dehydrocholesterol ≥95% (by HPLC)

Supplier: Van Der Voort Lucht en Milieu Amste

CDX-D0331-G010 CDX-D0331-G025
102989-778EA 113.54 USD InStock
102989-778 102989-780
7-Dehydrocholesterol ≥95% (by HPLC)
7-Dehydrocholesterol
Precursor of cholesterol and vitamin D3. It is reduced to cholesterol by the enzyme 3beta-hydroxysterol-Delta7-reductase (DHCR7) in the last step of cholesterol biosynthesis. Mutations in the gene encoding DHCR7 lead to increased levels of 7-DHC and the neurodevelopmental syndrome Smith-Lemli-Opitz syndrome (SLOS). 7-DHC is used as a biomarker for SLOS screenings. Inhibits human fibroblast sphingomyelinase. Shown to have cytotoxic effects on melanoma cells. In skin, photolysis of 7-DHC by ultraviolet light produces vitamin D3. UV/Vis: lambdamax 271, 282, 293nm.


Formula: C₂₇H₄₄O
Storage Temperature: Freezer
 MDL Number: MFCD00003624
CAS Number: 434-16-2
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Specification Test Results
Source/Host Synthetic
Purity 95% (HPLC)
Appearance/Color White powder.
Solubility Soluble in ethanol, chloroform or ethyl acetate. Slightly soluble in DMSO. Insoluble in water.

 

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