(S)-3-Amino-3-(3-nitrophenyl)propionic+acid
Supplier:
Adipogen
Description:
Immune response modifier. Potent antitumor and antiviral compound. Stimulates antibody secretion and cytokine production. Used as adjuvant to increase the effectiveness of vaccines. Potent and selective synthetic ligand for Toll-like receptor 7 (TLR7) in mouse and for TLR7 and TLR8 in human. Activates immune cells via the TLR7/TLR8 MyD88-dependent signaling pathway and leads to the induction of NF-kappaB. NLRP3/NALP3 inflammasome activator, independent of TLRs and RIG-I. Upregulator of the opioid growth factor receptor. Used in the treatment of skin lesions such as herpes simplex virus.
Catalog Number:
(89139-276)
Supplier:
Biotium
Description:
Zinquin is an UV-excitable, blue fluorescent zinc indicator. Zinquin ethyl ester is membrane-permeable and is hydrolyzed into Zinquin free acid once entering cells. Zinc is believed to be involved in the suppression of apoptosis and thought to play important roles in many neural activities.
Supplier:
BeanTown Chemical
Description:
CAS: 6104-58-1; EC No: 228-058-4; MDL No: MFCD00078482
Powder; Molecular Formula: C47H48N3NaO7S2; MW: 854.02
Supplier:
Matrix Scientific
Description:
MF=C5H9N3O MW=127.15 CAS=73616-27-0 MDL=MFCD08063809 5G
Catalog Number:
(89157-694)
Supplier:
Enzo Life Sciences
Description:
Dual 5-lipoxygenase (IC50=46.8 µM) and cyclooxygenase I and II inhibitor (IC50=0.6 µM). Clinically useful NSAID.
Supplier:
MP Biomedicals
Description:
(±)-Verapamil Hydrochloride is a α1-antagonist and calcium channel modulator.
Supplier:
MP Biomedicals
Description:
Methotrexate is a cell cycle arresting agent with varying effects. Methotrexate has been reported to arrest the cell cycle in late G1/S thus leading to the inhibition of the synthesis of DNA, RNA, thymidylates, and proteins. The main mechanism of action is reported to involve the inhibition of enzymes involved in purine metabolism which leads to the accumulation of adenosine or the suppression of intercellular adhesion molecule expression by T cells. Additionally, this compound has been observed to inhibit DHFR.
Methotrexate is used for chemotherapy either alone or in combination with other agents. It is effective for the treatment of a number of cancers including: breast, head and neck, leukemia, lymphoma, lung, osteosarcoma, bladder, and trophoblastic neoplasms. It is also used in treatment of autoimmune diseases, ectopic pregnancy, and for the induction of medical abortions. It is used to inhibit dihydrofolate reductase in DHFR-based protein expression systems. Also effective in treatment of pyrimethamine-resistant Plasmodium vivax malaria parasites. Potent inhibitor of dihydrofolate reductase and agent for antitumor studies. Use to inhibit dihydrofolate reductase in DHFR-based protein expression systems. Also shows immunosuppressive effects in, e.g., rheumatoid arthritis. Methotrexate is an allosteric inhibititor of dihydrofolate reductase (DHFR), the enzyme that catalyzes the conversion of dihydrofolate to tetrahydrofolate. Since tetrahydrolfolate is required for purine and pyrimidine synthesis, methotrexate treatment results in the inhibition of DNA and RNA synthesis.
Supplier:
TCI America
Description:
CAS Number: 42906-19-4
MDL Number: MFCD03093257 Molecular Formula: C21H19NO Molecular Weight: 301.39 Purity/Analysis Method: >98.0% (HPLC) Form: Crystal Melting point (°C): 109
Catalog Number:
(PI20279)
Supplier:
Invitrogen
Description:
Thermo Scientific Pierce Coomassie Brilliant Blue G-250 is one of the most common forms of coomassie dye, which is a key component of various colorimetric protein gel stains.
Catalog Number:
(TS46280-1000)
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
Lumiracoxib
Supplier:
ALADDIN SCIENTIFIC
Description:
AZ 628 ≥98%, Moligand™
Catalog Number:
(TCB0490-025G)
Supplier:
TCI America
Description:
CAS Number: 92-00-2
MDL Number: MFCD00002852 Molecular Formula: C10H14ClNO2 Molecular Weight: 215.68 Purity/Analysis Method: >90.0% (GC) Form: Crystal Melting point (°C): 84
Supplier:
Spectrum Chemicals
Description:
Triethanolamine, Reagent is a is colorless organic compound that has a viscous texture and is both a tertiary amine and a triol. It is mainly used as an emulsifier and a surfactant. It neutralizes fatty acids while adjusting and buffering the pH. It is used in the fabrication of cosmetics and medicine such as ear drops, skin lotions, eye gels, shampoos and others. It also has a use in the laboratory as a complexing agent for aluminum ions in aqueous solutions. Its reagent grade means this is the highest quality commercially available for this chemical and that the American Chemical Society has not officially set any specifications for this material.
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Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
Coomassie brilliant blue G-250, pure
Catalog Number:
(TCT0254-25G)
Supplier:
TCI America
Description:
CAS Number: 612-82-8
MDL Number: MFCD00012960 Molecular Formula: C14H16N2 Molecular Weight: 285.21 Purity/Analysis Method: >98.0% (T) Form: Crystal Color: White
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